Crystal Structure of This DT
Crystallisation Method:EM
Corresponding Chain:A
Sequence Length:2-630
Detail: Struture Info
Detail Information of Inter-species Structural Difference
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0352 Transporter Info | ||||
| Gene Name | SLC3A2 | ||||
| Protein Name | Lymphocyte activation antigen 4F2 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Slc3a2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure | |||||
| Click to Save PDB File in PDB Format | |||||
| Experimental Structures of This Model Oganism | |||||
| PDB ID | Scanning Method | Resolution | Expression System | Details | Ref |
| 6SUA | X-ray | 2.75 Å | Escherichia coli | [ 1] | |
| Structure | |||||
| Click to Save PDB File in TXT Format | |||||
| Corresponding chain | B/D | ||||
| Sequence Length | 105-526 | Mutation | Yes | ||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Slc3a2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6JMQ_B Sequence Length:527 Identity:75.985% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1331.171 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.36 ±0.34 Residues in Favored Region:508 Ramachandran favored:96.76% Number of Outliers:1 Ramachandran outliers:0.19% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Oryctolagus cuniculus (Rabbit) | |||||
| Gene Name | SLC3A2 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6JMQ_B Sequence Length:529 Identity:82.364% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -1409.074 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.62 ±0.35 Residues in Favored Region:513 Ramachandran favored:97.34% Number of Outliers:3 Ramachandran outliers:0.57% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.76 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice. Protein Sci. 2020 Aug;29(8):1774-1783. | ||||
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