Crystal Structure of This DT
Crystallisation Method:EM
Corresponding Chain:A/B
Sequence Length:50-369
Detail: Struture Info
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0035 Transporter Info | ||||
| Gene Name | SLC30A8 | ||||
| Protein Name | Zinc transporter 8 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| 3D Structure |
Crystal Structure of This DT Crystallisation Method:EM Corresponding Chain:A/B Sequence Length:50-369 Detail: Struture Info |
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| Inter-species Structural Differences (ISD) | |||||
| Mus musculus (Mouse) | |||||
| Gene Name | Slc30a8 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6XPE_A Sequence Length:319 Identity:81.25% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -743.744 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.86 ±0.41 Residues in Favored Region:307 Ramachandran favored:96.85% Number of Outliers:2 Ramachandran outliers:0.63% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.79 |
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| Click to Save Local Quality Plot in PNG Format | |||||
| Rattus norvegicus (Rat) | |||||
| Gene Name | Slc30a8 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6XPE_A Sequence Length:320 Identity:79.375% |
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| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -796.013 kcal/mol | |||
| Ramachandra Favored | Medium |
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| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-0.55 ±0.44 Residues in Favored Region:305 Ramachandran favored:95.91% Number of Outliers:2 Ramachandran outliers:0.63% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.79 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
| Xenopus laevis (African clawed frog) | |||||
| Gene Name | slc30a8 | ||||
| UniProt ID | |||||
| UniProt Entry | |||||
| 3D Structure |
Method:Homology modeling Teplate PDB:6XPE_A Sequence Length:329 Identity:61.094% |
||||
| Click to Save PDB File in TXT Format | |||||
| Performance | Minimized Score | -745.573 kcal/mol | |||
| Ramachandra Favored | Medium |
||||
| QMEANBrane Quality | Medium |
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| Ramachandran Plot |
Ramz Z Score:-1.48 ±0.41 Residues in Favored Region:312 Ramachandran favored:95.41% Number of Outliers:4 Ramachandran outliers:1.22% |
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| Click to Save Ramachandran Plot in PNG Format | |||||
| Local Quality |
QMEANBrane Score:0.79 |
||||
| Click to Save Local Quality Plot in PNG Format | |||||
| References | |||||
| 1 | Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn(2+)-releasing mechanism. J Struct Biol. 2023;215(1):107926. | ||||
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