Detail Information of Genetic Polymorphisms
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0322 Transporter Info | ||||
| Gene Name | SLC37A1 | ||||
| Protein Name | Glycerol-3-phosphate permease | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Genetic Polymorphisms of DT (GPD) | |||||
| Genetic Polymorphism | rs35112095 | ||||
| Site of GPD | chr21:42569923 (GRCh38.p12) | ||||
| GPD Type | SNP | ||||
| Allele(s) in dbSNP | G>A | ||||
| Minor Allele Frequency | G=0.9880/1955 (Global) | ||||
| Allele G | Click to Show/Hide the Full List of Affected Drugs: 2 Drugs in Total | ||||
| Anastrozole | N.A. | Fractures, Bone | Allele G is not associated with risk of Fractures, Bone when exposed to anastrozole and exemestane in women with Breast Neoplasms as compared to allele A. | [ 1] | |
| Exemestane | N.A. | Fractures, Bone | Allele G is not associated with risk of Fractures, Bone when exposed to anastrozole and exemestane in women with Breast Neoplasms as compared to allele A. | [ 1] | |
| References | |||||
| 1 | Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics. Mol Endocrinol. 2014 Oct;28(10):1740-51. | ||||
If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.