General Information of Drug Transporter (DT)
DT ID DTD0537 Transporter Info
Gene Name RALBP1
Transporter Name RalBP1-associated Eps domain-containing protein 2
Gene ID
10928
UniProt ID
Q8NFH8
Epigenetic Regulations of This DT (EGR)

Methylation

  Atypical teratoid rhabdoid tumor

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg03236570)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:1.41E-08; Z-score:-1.06E+00

Methylation in Case

8.23E-01 (Median) Methylation in Control 8.76E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg05121812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.17E+00 Statistic Test p-value:4.42E-08; Z-score:1.67E+00

Methylation in Case

9.07E-01 (Median) Methylation in Control 7.74E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg12907513)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.12E+00 Statistic Test p-value:4.06E-07; Z-score:8.35E-01

Methylation in Case

8.84E-01 (Median) Methylation in Control 7.89E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg15947599)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.50E+00 Statistic Test p-value:1.61E-06; Z-score:9.42E-01

Methylation in Case

2.30E-01 (Median) Methylation in Control 1.53E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg19013594)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.44E+00 Statistic Test p-value:2.69E-06; Z-score:-1.13E+00

Methylation in Case

4.64E-01 (Median) Methylation in Control 6.67E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

5'UTR (cg21200923)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:4.98E-06; Z-score:-8.00E-01

Methylation in Case

8.73E-01 (Median) Methylation in Control 8.93E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of RALBP1 in atypical teratoid rhabdoid tumor [ 1 ]

Location

3'UTR (cg13272780)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.08E+00 Statistic Test p-value:2.55E-11; Z-score:-1.76E+00

Methylation in Case

8.36E-01 (Median) Methylation in Control 9.03E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Bladder cancer

           9 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

5'UTR (cg05121812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.10E+00 Statistic Test p-value:2.22E-06; Z-score:-6.21E+00

Methylation in Case

7.71E-01 (Median) Methylation in Control 8.49E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

5'UTR (cg21200923)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.66E-02; Z-score:-9.65E-01

Methylation in Case

7.98E-01 (Median) Methylation in Control 8.31E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

5'UTR (cg12907513)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.83E-02; Z-score:-2.55E+00

Methylation in Case

8.93E-01 (Median) Methylation in Control 9.13E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

TSS1500 (cg21923525)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.68E+00 Statistic Test p-value:1.60E-10; Z-score:-1.36E+01

Methylation in Case

4.18E-01 (Median) Methylation in Control 7.04E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

TSS1500 (cg13993179)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.43E+00 Statistic Test p-value:1.32E-06; Z-score:-9.51E+00

Methylation in Case

5.60E-01 (Median) Methylation in Control 8.01E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.32E+00 Statistic Test p-value:3.05E-02; Z-score:-2.69E+00

Methylation in Case

1.78E-01 (Median) Methylation in Control 2.35E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

TSS200 (cg06753227)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:5.80E-05; Z-score:-3.60E+00

Methylation in Case

4.58E-01 (Median) Methylation in Control 4.88E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

Body (cg16300329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.12E+00 Statistic Test p-value:6.73E-03; Z-score:1.36E+00

Methylation in Case

6.46E-01 (Median) Methylation in Control 5.78E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of RALBP1 in bladder cancer [ 2 ]

Location

3'UTR (cg13272780)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:7.00E-06; Z-score:-5.06E+00

Methylation in Case

8.15E-01 (Median) Methylation in Control 8.74E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Breast cancer

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in breast cancer [ 3 ]

Location

5'UTR (cg05121812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:3.95E-05; Z-score:1.18E+00

Methylation in Case

8.49E-01 (Median) Methylation in Control 8.26E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in breast cancer [ 3 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.73E+00 Statistic Test p-value:3.38E-16; Z-score:3.76E+00

Methylation in Case

3.51E-01 (Median) Methylation in Control 2.02E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in breast cancer [ 3 ]

Location

TSS200 (cg22466830)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.26E+00 Statistic Test p-value:1.05E-02; Z-score:5.61E-01

Methylation in Case

1.50E-02 (Median) Methylation in Control 1.19E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in breast cancer [ 3 ]

Location

TSS200 (cg05854894)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.32E+00 Statistic Test p-value:2.73E-02; Z-score:-4.79E-01

Methylation in Case

1.04E-02 (Median) Methylation in Control 1.37E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in breast cancer [ 3 ]

Location

Body (cg16300329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.27E+00 Statistic Test p-value:3.49E-23; Z-score:3.45E+00

Methylation in Case

7.20E-01 (Median) Methylation in Control 5.67E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in breast cancer [ 3 ]

Location

3'UTR (cg13272780)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:3.24E-04; Z-score:-8.41E-01

Methylation in Case

8.55E-01 (Median) Methylation in Control 8.83E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Renal cell carcinoma

           4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in clear cell renal cell carcinoma [ 4 ]

Location

5'UTR (cg05121812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.02E+00 Statistic Test p-value:7.33E-05; Z-score:1.62E+00

Methylation in Case

9.50E-01 (Median) Methylation in Control 9.31E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in clear cell renal cell carcinoma [ 4 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.63E+00 Statistic Test p-value:6.37E-07; Z-score:1.99E+00

Methylation in Case

3.38E-01 (Median) Methylation in Control 2.08E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in clear cell renal cell carcinoma [ 4 ]

Location

TSS1500 (cg13993179)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.14E+00 Statistic Test p-value:2.12E-03; Z-score:2.36E+00

Methylation in Case

9.17E-01 (Median) Methylation in Control 8.02E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in clear cell renal cell carcinoma [ 4 ]

Location

TSS200 (cg22466830)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.05E+00 Statistic Test p-value:4.41E-03; Z-score:4.66E-01

Methylation in Case

1.66E-02 (Median) Methylation in Control 1.58E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Hepatocellular carcinoma

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

5'UTR (cg05121812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.00E+00 Statistic Test p-value:3.16E-02; Z-score:2.92E-02

Methylation in Case

8.52E-01 (Median) Methylation in Control 8.51E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.21E+00 Statistic Test p-value:3.95E-06; Z-score:2.01E+00

Methylation in Case

4.93E-01 (Median) Methylation in Control 4.08E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

TSS1500 (cg21923525)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:1.87E-03; Z-score:-1.00E+00

Methylation in Case

6.59E-01 (Median) Methylation in Control 7.01E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

TSS200 (cg06753227)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:2.48E-02; Z-score:-2.24E-01

Methylation in Case

4.01E-01 (Median) Methylation in Control 4.09E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

Body (cg22359828)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.04E+00 Statistic Test p-value:5.71E-21; Z-score:-3.89E+00

Methylation in Case

2.12E-01 (Median) Methylation in Control 4.33E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in hepatocellular carcinoma [ 5 ]

Location

3'UTR (cg13272780)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:9.40E-03; Z-score:-4.23E-01

Methylation in Case

8.63E-01 (Median) Methylation in Control 8.75E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  HIV infection

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in HIV infection [ 6 ]

Location

5'UTR (cg12907513)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:4.26E-02; Z-score:-4.50E-01

Methylation in Case

9.14E-01 (Median) Methylation in Control 9.22E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in HIV infection [ 6 ]

Location

TSS1500 (cg21923525)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.67E+00 Statistic Test p-value:1.71E-08; Z-score:4.39E+00

Methylation in Case

5.66E-01 (Median) Methylation in Control 3.40E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in HIV infection [ 6 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.23E+00 Statistic Test p-value:2.16E-05; Z-score:1.62E+00

Methylation in Case

5.51E-01 (Median) Methylation in Control 4.47E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in HIV infection [ 6 ]

Location

TSS1500 (cg18989081)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.27E+00 Statistic Test p-value:6.98E-04; Z-score:1.34E+00

Methylation in Case

1.20E-01 (Median) Methylation in Control 9.42E-02 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in HIV infection [ 6 ]

Location

TSS1500 (cg13993179)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.00E+00 Statistic Test p-value:4.72E-02; Z-score:1.28E-01

Methylation in Case

8.58E-01 (Median) Methylation in Control 8.55E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in HIV infection [ 6 ]

Location

Body (cg16300329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:3.18E-03; Z-score:-8.57E-01

Methylation in Case

9.56E-01 (Median) Methylation in Control 9.66E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Prostate cancer

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in prostate cancer [ 7 ]

Location

5'UTR (cg10829727)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:3.24E+00 Statistic Test p-value:2.76E-03; Z-score:3.74E+01

Methylation in Case

5.10E-01 (Median) Methylation in Control 1.57E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in prostate cancer [ 7 ]

Location

Body (cg21522289)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:7.17E-03; Z-score:2.68E+00

Methylation in Case

9.21E-01 (Median) Methylation in Control 8.57E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Colorectal cancer

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

TSS1500 (cg21923525)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.20E+00 Statistic Test p-value:1.69E-12; Z-score:-3.64E+00

Methylation in Case

7.08E-01 (Median) Methylation in Control 8.50E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

TSS200 (cg12799349)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.14E+00 Statistic Test p-value:2.34E-05; Z-score:1.07E+00

Methylation in Case

7.83E-02 (Median) Methylation in Control 6.86E-02 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

TSS200 (cg22466830)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.37E+00 Statistic Test p-value:2.96E-03; Z-score:1.19E+00

Methylation in Case

1.56E-02 (Median) Methylation in Control 1.14E-02 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

TSS200 (cg06753227)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.13E+00 Statistic Test p-value:4.80E-03; Z-score:7.03E-01

Methylation in Case

3.98E-01 (Median) Methylation in Control 3.54E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

TSS200 (cg09664812)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.09E+00 Statistic Test p-value:2.72E-02; Z-score:4.78E-01

Methylation in Case

1.07E-01 (Median) Methylation in Control 9.77E-02 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of RALBP1 in colorectal cancer [ 8 ]

Location

Body (cg16300329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.14E+00 Statistic Test p-value:9.96E-03; Z-score:-9.62E-01

Methylation in Case

8.08E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Lung adenocarcinoma

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in lung adenocarcinoma [ 9 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.22E+00 Statistic Test p-value:1.95E-03; Z-score:2.32E+00

Methylation in Case

5.33E-01 (Median) Methylation in Control 4.37E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Pancretic ductal adenocarcinoma

           4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in pancretic ductal adenocarcinoma [ 10 ]

Location

TSS1500 (cg03307893)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:3.92E+00 Statistic Test p-value:7.88E-06; Z-score:1.77E+00

Methylation in Case

3.28E-01 (Median) Methylation in Control 8.38E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in pancretic ductal adenocarcinoma [ 10 ]

Location

Body (cg12106894)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.05E-07; Z-score:-1.14E+00

Methylation in Case

8.86E-01 (Median) Methylation in Control 9.05E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in pancretic ductal adenocarcinoma [ 10 ]

Location

Body (cg01316792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:2.16E-03; Z-score:1.40E+00

Methylation in Case

8.24E-01 (Median) Methylation in Control 7.99E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in pancretic ductal adenocarcinoma [ 10 ]

Location

Body (cg24045078)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:1.06E-02; Z-score:-1.23E-01

Methylation in Case

8.29E-01 (Median) Methylation in Control 8.31E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Panic disorder

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in panic disorder [ 11 ]

Location

TSS1500 (cg21923525)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-9.01E-01 Statistic Test p-value:1.59E-02; Z-score:-3.56E-01

Methylation in Case

-1.55E+00 (Median) Methylation in Control -1.39E+00 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in panic disorder [ 11 ]

Location

TSS1500 (cg15982419)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-6.95E-01 Statistic Test p-value:4.04E-02; Z-score:-3.36E-01

Methylation in Case

-7.52E-01 (Median) Methylation in Control -5.22E-01 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Papillary thyroid cancer

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in papillary thyroid cancer [ 12 ]

Location

TSS1500 (cg13993179)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.05E+00 Statistic Test p-value:7.96E-04; Z-score:1.34E+00

Methylation in Case

8.86E-01 (Median) Methylation in Control 8.46E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in papillary thyroid cancer [ 12 ]

Location

3'UTR (cg13272780)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.28E-03; Z-score:-5.25E-01

Methylation in Case

9.00E-01 (Median) Methylation in Control 9.09E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Systemic lupus erythematosus

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in systemic lupus erythematosus [ 13 ]

Location

TSS1500 (cg13993179)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:4.93E-04; Z-score:-3.59E-01

Methylation in Case

8.80E-01 (Median) Methylation in Control 8.90E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Colon cancer

           4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of RALBP1 in colon adenocarcinoma [ 14 ]

Location

TSS200 (cg04299028)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.20E+00 Statistic Test p-value:3.77E-04; Z-score:-2.58E+00

Methylation in Case

6.71E-01 (Median) Methylation in Control 8.04E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of RALBP1 in colon adenocarcinoma [ 14 ]

Location

Body (cg18426477)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.36E+00 Statistic Test p-value:1.02E-06; Z-score:-4.46E+00

Methylation in Case

4.27E-01 (Median) Methylation in Control 5.81E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of RALBP1 in colon adenocarcinoma [ 14 ]

Location

Body (cg04437482)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.13E+00 Statistic Test p-value:6.90E-04; Z-score:-3.25E+00

Methylation in Case

6.23E-01 (Median) Methylation in Control 7.01E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of RALBP1 in colon adenocarcinoma [ 14 ]

Location

3'UTR (cg18377941)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.29E+00 Statistic Test p-value:2.71E-05; Z-score:-2.61E+00

Methylation in Case

5.82E-01 (Median) Methylation in Control 7.48E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

microRNA

  Unclear Phenotype

         23 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

miR-10a directly targets RALBP1 [ 15 ]

Epigenetic Type

microRNA Experiment Method CLASH

miRNA Stemloop ID

miR-10a miRNA Mature ID miR-10a-5p

miRNA Sequence

UACCCUGUAGAUCCGAAUUUGUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon2

miR-10b directly targets RALBP1 [ 15 ]

Epigenetic Type

microRNA Experiment Method CLASH

miRNA Stemloop ID

miR-10b miRNA Mature ID miR-10b-5p

miRNA Sequence

UACCCUGUAGAACCGAAUUUGUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon3

miR-125a directly targets RALBP1 [ 15 ]

Epigenetic Type

microRNA Experiment Method CLASH

miRNA Stemloop ID

miR-125a miRNA Mature ID miR-125a-5p

miRNA Sequence

UCCCUGAGACCCUUUAACCUGUGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon4

miR-185 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-185 miRNA Mature ID miR-185-5p

miRNA Sequence

UGGAGAGAAAGGCAGUUCCUGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon5

miR-1914 directly targets RALBP1 [ 15 ]

Epigenetic Type

microRNA Experiment Method CLASH

miRNA Stemloop ID

miR-1914 miRNA Mature ID miR-1914-5p

miRNA Sequence

CCCUGUGCCCGGCCCACUUCUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon6

miR-298 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-298 miRNA Mature ID miR-298

miRNA Sequence

AGCAGAAGCAGGGAGGUUCUCCCA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon7

miR-3158 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-3158 miRNA Mature ID miR-3158-5p

miRNA Sequence

CCUGCAGAGAGGAAGCCCUUC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon8

miR-4306 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4306 miRNA Mature ID miR-4306

miRNA Sequence

UGGAGAGAAAGGCAGUA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon9

miR-4418 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4418 miRNA Mature ID miR-4418

miRNA Sequence

CACUGCAGGACUCAGCAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon10

miR-4428 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4428 miRNA Mature ID miR-4428

miRNA Sequence

CAAGGAGACGGGAACAUGGAGC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon11

miR-4481 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4481 miRNA Mature ID miR-4481

miRNA Sequence

GGAGUGGGCUGGUGGUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon12

miR-4640 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4640 miRNA Mature ID miR-4640-5p

miRNA Sequence

UGGGCCAGGGAGCAGCUGGUGGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon13

miR-4644 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4644 miRNA Mature ID miR-4644

miRNA Sequence

UGGAGAGAGAAAAGAGACAGAAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon14

miR-4693 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4693 miRNA Mature ID miR-4693-3p

miRNA Sequence

UGAGAGUGGAAUUCACAGUAUUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon15

miR-4726 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4726 miRNA Mature ID miR-4726-5p

miRNA Sequence

AGGGCCAGAGGAGCCUGGAGUGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon16

miR-4745 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4745 miRNA Mature ID miR-4745-5p

miRNA Sequence

UGAGUGGGGCUCCCGGGACGGCG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon17

miR-4784 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4784 miRNA Mature ID miR-4784

miRNA Sequence

UGAGGAGAUGCUGGGACUGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon18

miR-509 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-509 miRNA Mature ID miR-509-5p

miRNA Sequence

UACUGCAGACAGUGGCAAUCA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon19

miR-5192 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-5192 miRNA Mature ID miR-5192

miRNA Sequence

AGGAGAGUGGAUUCCAGGUGGU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon20

miR-615 directly targets RALBP1 [ 15 ]

Epigenetic Type

microRNA Experiment Method CLASH

miRNA Stemloop ID

miR-615 miRNA Mature ID miR-615-3p

miRNA Sequence

UCCGAGCCUGGGUCUCCCUCUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon21

miR-6508 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6508 miRNA Mature ID miR-6508-3p

miRNA Sequence

UGGGCCAUGCAUUUCUAGAACU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon22

miR-6758 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6758 miRNA Mature ID miR-6758-5p

miRNA Sequence

UAGAGAGGGGAAGGAUGUGAUGU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon23

miR-6856 directly targets RALBP1 [ 16 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6856 miRNA Mature ID miR-6856-5p

miRNA Sequence

AAGAGAGGAGCAGUGGUGCUGUGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human
References
1 Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
2 DNA Methylation Dynamics in Urological Tumors.
3 Genome-wide Scan for Methylation Profiles in Breast Cancer
4 A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
5 Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
6 HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
7 Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
8 Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
9 DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
10 Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
11 DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
12 Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
13 Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9(8):e1003678.
14 Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
15 Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell. 2013 Apr 25;153(3):654-65.
16 TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network. Genome Res. 2016 Mar;26(3):331-41.

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