General Information of Drug Transporter (DT)
DT ID DTD0527 Transporter Info
Gene Name SCN4A
Transporter Name Voltage-gated sodium channel alpha Nav1.4
Gene ID
6329
UniProt ID
P35499
Epigenetic Regulations of This DT (EGR)

Methylation

  Hepatocellular carcinoma

         17 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

5'UTR (cg24499516)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.24E+00 Statistic Test p-value:6.35E-10; Z-score:-2.42E+00

Methylation in Case

5.50E-01 (Median) Methylation in Control 6.81E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

TSS200 (cg22499001)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:4.83E-07; Z-score:-2.16E+00

Methylation in Case

8.18E-01 (Median) Methylation in Control 8.59E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

TSS200 (cg23387800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:1.37E-06; Z-score:-2.03E+00

Methylation in Case

7.59E-01 (Median) Methylation in Control 7.98E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

TSS200 (cg23722792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.76E-05; Z-score:-9.77E-01

Methylation in Case

7.87E-01 (Median) Methylation in Control 8.16E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg26426186)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.01E+00 Statistic Test p-value:2.67E-24; Z-score:-7.33E+00

Methylation in Case

3.46E-01 (Median) Methylation in Control 6.97E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg14688430)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.48E+00 Statistic Test p-value:2.80E-19; Z-score:-7.44E+00

Methylation in Case

5.10E-01 (Median) Methylation in Control 7.53E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg14239111)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.39E+00 Statistic Test p-value:1.09E-13; Z-score:-9.43E+00

Methylation in Case

6.68E-01 (Median) Methylation in Control 9.29E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg22571065)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.37E+00 Statistic Test p-value:2.39E-13; Z-score:-3.15E+00

Methylation in Case

3.44E-01 (Median) Methylation in Control 4.72E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg09310092)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.24E+00 Statistic Test p-value:4.03E-12; Z-score:2.05E+00

Methylation in Case

6.68E-01 (Median) Methylation in Control 5.38E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg16146033)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.35E+00 Statistic Test p-value:5.37E-11; Z-score:-1.45E+00

Methylation in Case

2.17E-01 (Median) Methylation in Control 2.94E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg26840162)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.14E+00 Statistic Test p-value:8.07E-09; Z-score:-3.94E+00

Methylation in Case

7.55E-01 (Median) Methylation in Control 8.65E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg21091640)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:2.75E-08; Z-score:-1.08E+00

Methylation in Case

8.46E-01 (Median) Methylation in Control 9.01E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg26503701)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.09E+00 Statistic Test p-value:2.10E-06; Z-score:-6.49E-01

Methylation in Case

7.45E-01 (Median) Methylation in Control 8.12E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg17295589)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:8.20E-06; Z-score:-1.07E+00

Methylation in Case

9.43E-01 (Median) Methylation in Control 9.62E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg17527484)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.15E+00 Statistic Test p-value:1.44E-03; Z-score:3.57E-01

Methylation in Case

2.24E-01 (Median) Methylation in Control 1.95E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon16

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

Body (cg19881928)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.18E+00 Statistic Test p-value:3.91E-03; Z-score:4.61E-01

Methylation in Case

1.59E-01 (Median) Methylation in Control 1.35E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon17

Methylation of SCN4A in hepatocellular carcinoma [ 1 ]

Location

3'UTR (cg03917100)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.12E+00 Statistic Test p-value:5.36E-09; Z-score:-2.95E+00

Methylation in Case

7.08E-01 (Median) Methylation in Control 7.93E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Pancretic ductal adenocarcinoma

         16 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

5'UTR (cg27348223)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:4.52E+00 Statistic Test p-value:1.61E-45; Z-score:7.93E+00

Methylation in Case

2.68E-01 (Median) Methylation in Control 5.94E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

5'UTR (cg08190044)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.53E+00 Statistic Test p-value:2.11E-20; Z-score:4.32E+00

Methylation in Case

2.14E-01 (Median) Methylation in Control 8.47E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

TSS1500 (cg04944393)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.08E+00 Statistic Test p-value:8.51E-09; Z-score:-1.37E+00

Methylation in Case

7.58E-01 (Median) Methylation in Control 8.16E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

TSS1500 (cg04396550)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:2.83E-08; Z-score:5.44E-01

Methylation in Case

4.83E-02 (Median) Methylation in Control 4.41E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

TSS1500 (cg25846723)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.43E+00 Statistic Test p-value:2.55E-04; Z-score:1.19E+00

Methylation in Case

2.99E-01 (Median) Methylation in Control 1.23E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

TSS1500 (cg12133952)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.15E+00 Statistic Test p-value:2.85E-02; Z-score:-5.09E-01

Methylation in Case

2.16E-01 (Median) Methylation in Control 2.49E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

TSS200 (cg02079377)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.25E+00 Statistic Test p-value:2.03E-12; Z-score:1.32E+00

Methylation in Case

8.63E-02 (Median) Methylation in Control 6.89E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

1stExon (cg13694749)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.22E+00 Statistic Test p-value:8.70E-07; Z-score:1.59E+00

Methylation in Case

7.90E-01 (Median) Methylation in Control 6.45E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg17812026)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.16E-19; Z-score:-4.56E+00

Methylation in Case

9.26E-01 (Median) Methylation in Control 9.67E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg08581937)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.81E+00 Statistic Test p-value:1.73E-19; Z-score:2.71E+00

Methylation in Case

9.99E-02 (Median) Methylation in Control 5.50E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg01359329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:1.38E-07; Z-score:-1.30E+00

Methylation in Case

6.96E-01 (Median) Methylation in Control 7.74E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg21334510)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.24E+00 Statistic Test p-value:1.40E-07; Z-score:-1.58E+00

Methylation in Case

4.85E-01 (Median) Methylation in Control 6.04E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg02303265)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:1.55E-04; Z-score:9.80E-01

Methylation in Case

8.69E-01 (Median) Methylation in Control 8.11E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg19172170)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:1.87E-03; Z-score:8.08E-01

Methylation in Case

3.84E-01 (Median) Methylation in Control 3.49E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg27470827)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.08E+00 Statistic Test p-value:2.02E-02; Z-score:6.24E-01

Methylation in Case

7.24E-01 (Median) Methylation in Control 6.71E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon16

Methylation of SCN4A in pancretic ductal adenocarcinoma [ 2 ]

Location

Body (cg04467119)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:2.55E-02; Z-score:-3.21E-01

Methylation in Case

7.93E-01 (Median) Methylation in Control 8.02E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Prostate cancer

           8 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in prostate cancer [ 3 ]

Location

5'UTR (cg14313833)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:1.77E-02; Z-score:2.64E+00

Methylation in Case

9.45E-01 (Median) Methylation in Control 9.20E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in prostate cancer [ 3 ]

Location

TSS1500 (cg14019050)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.20E+00 Statistic Test p-value:2.08E-02; Z-score:3.68E+00

Methylation in Case

7.71E-01 (Median) Methylation in Control 6.45E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in prostate cancer [ 3 ]

Location

TSS1500 (cg12572677)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.02E+00 Statistic Test p-value:3.54E-02; Z-score:1.36E+00

Methylation in Case

9.16E-01 (Median) Methylation in Control 8.97E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in prostate cancer [ 3 ]

Location

TSS200 (cg10717290)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.34E+00 Statistic Test p-value:4.32E-02; Z-score:1.94E+00

Methylation in Case

9.62E-02 (Median) Methylation in Control 7.19E-02 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in prostate cancer [ 3 ]

Location

Body (cg26138846)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.78E+00 Statistic Test p-value:2.60E-03; Z-score:-6.10E+00

Methylation in Case

4.52E-01 (Median) Methylation in Control 8.07E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in prostate cancer [ 3 ]

Location

Body (cg06637017)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:1.95E-02; Z-score:2.40E+00

Methylation in Case

9.18E-01 (Median) Methylation in Control 8.61E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in prostate cancer [ 3 ]

Location

Body (cg05908380)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.54E+00 Statistic Test p-value:2.62E-02; Z-score:6.30E+00

Methylation in Case

2.03E-01 (Median) Methylation in Control 7.99E-02 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in prostate cancer [ 3 ]

Location

Body (cg00844950)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.98E+00 Statistic Test p-value:3.55E-02; Z-score:-2.07E+00

Methylation in Case

5.54E-02 (Median) Methylation in Control 1.10E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Bladder cancer

         22 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS1500 (cg14258078)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.60E+00 Statistic Test p-value:1.60E-15; Z-score:-2.35E+01

Methylation in Case

2.73E-01 (Median) Methylation in Control 7.09E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS1500 (cg25507121)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.85E+00 Statistic Test p-value:4.17E-15; Z-score:-1.95E+01

Methylation in Case

2.07E-01 (Median) Methylation in Control 5.89E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS1500 (cg05818824)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-3.12E+00 Statistic Test p-value:5.85E-14; Z-score:-1.40E+01

Methylation in Case

1.74E-01 (Median) Methylation in Control 5.44E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.50E+00 Statistic Test p-value:3.65E-09; Z-score:-1.68E+01

Methylation in Case

5.15E-01 (Median) Methylation in Control 7.71E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS200 (cg23722792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:1.62E-04; Z-score:-3.14E+00

Methylation in Case

7.79E-01 (Median) Methylation in Control 8.26E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS200 (cg22499001)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.68E-04; Z-score:-2.88E+00

Methylation in Case

8.28E-01 (Median) Methylation in Control 8.63E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in bladder cancer [ 4 ]

Location

TSS200 (cg23387800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:7.96E-03; Z-score:-1.32E+00

Methylation in Case

7.72E-01 (Median) Methylation in Control 7.94E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in bladder cancer [ 4 ]

Location

1stExon (cg13694749)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.34E+00 Statistic Test p-value:1.36E-06; Z-score:-7.78E+00

Methylation in Case

5.79E-01 (Median) Methylation in Control 7.74E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.99E+00 Statistic Test p-value:5.32E-15; Z-score:-2.26E+01

Methylation in Case

3.36E-01 (Median) Methylation in Control 6.69E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg09760889)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.40E+00 Statistic Test p-value:1.20E-08; Z-score:-1.28E+01

Methylation in Case

5.59E-01 (Median) Methylation in Control 7.84E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg05367173)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.59E+00 Statistic Test p-value:3.12E-07; Z-score:-3.86E+01

Methylation in Case

5.63E-01 (Median) Methylation in Control 8.94E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg26840162)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:1.39E-06; Z-score:-7.27E+00

Methylation in Case

8.05E-01 (Median) Methylation in Control 8.93E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg16760172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.20E+00 Statistic Test p-value:3.71E-06; Z-score:-7.19E+00

Methylation in Case

7.53E-01 (Median) Methylation in Control 9.04E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg25601446)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.17E+00 Statistic Test p-value:5.91E-06; Z-score:-4.60E+00

Methylation in Case

6.95E-01 (Median) Methylation in Control 8.15E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg23529278)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.10E+00 Statistic Test p-value:3.09E-05; Z-score:-1.15E+01

Methylation in Case

8.30E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon16

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg18948221)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.09E+00 Statistic Test p-value:8.16E-04; Z-score:-3.37E+00

Methylation in Case

7.79E-01 (Median) Methylation in Control 8.47E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon17

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg09247259)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:3.02E-03; Z-score:-2.45E+00

Methylation in Case

9.01E-01 (Median) Methylation in Control 9.16E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon18

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg20433103)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:5.80E-03; Z-score:-2.67E+00

Methylation in Case

8.64E-01 (Median) Methylation in Control 9.01E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon19

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg17527484)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.07E+00 Statistic Test p-value:1.52E-02; Z-score:-1.95E+00

Methylation in Case

5.49E-02 (Median) Methylation in Control 1.14E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon20

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg17295589)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.90E-02; Z-score:-1.71E+00

Methylation in Case

9.47E-01 (Median) Methylation in Control 9.61E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon21

Methylation of SCN4A in bladder cancer [ 4 ]

Location

Body (cg21091640)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:4.98E-02; Z-score:-1.96E+00

Methylation in Case

8.92E-01 (Median) Methylation in Control 9.18E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon22

Methylation of SCN4A in bladder cancer [ 4 ]

Location

3'UTR (cg03917100)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.18E+00 Statistic Test p-value:1.38E-06; Z-score:-6.56E+00

Methylation in Case

6.12E-01 (Median) Methylation in Control 7.24E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Breast cancer

         22 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in breast cancer [ 5 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:2.61E-11; Z-score:-2.52E+00

Methylation in Case

6.67E-01 (Median) Methylation in Control 7.40E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in breast cancer [ 5 ]

Location

TSS200 (cg23722792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:4.57E-05; Z-score:-8.40E-01

Methylation in Case

7.98E-01 (Median) Methylation in Control 8.18E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in breast cancer [ 5 ]

Location

TSS200 (cg22499001)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:2.31E-03; Z-score:-8.68E-01

Methylation in Case

8.18E-01 (Median) Methylation in Control 8.57E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in breast cancer [ 5 ]

Location

TSS200 (cg23387800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:4.32E-02; Z-score:-7.50E-01

Methylation in Case

7.63E-01 (Median) Methylation in Control 8.05E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in breast cancer [ 5 ]

Location

1stExon (cg13694749)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.13E+00 Statistic Test p-value:3.45E-09; Z-score:-2.53E+00

Methylation in Case

6.59E-01 (Median) Methylation in Control 7.46E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.45E+00 Statistic Test p-value:3.03E-24; Z-score:-4.38E+00

Methylation in Case

4.48E-01 (Median) Methylation in Control 6.50E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg26840162)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:4.42E-11; Z-score:-2.61E+00

Methylation in Case

8.19E-01 (Median) Methylation in Control 8.74E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg05367173)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.10E+00 Statistic Test p-value:3.15E-10; Z-score:-2.26E+00

Methylation in Case

7.96E-01 (Median) Methylation in Control 8.77E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg26503701)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:3.36E-09; Z-score:-1.82E+00

Methylation in Case

7.61E-01 (Median) Methylation in Control 8.12E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg19881928)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.86E+00 Statistic Test p-value:2.06E-08; Z-score:1.57E+00

Methylation in Case

2.66E-01 (Median) Methylation in Control 1.43E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg20433103)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:2.24E-07; Z-score:-1.49E+00

Methylation in Case

8.54E-01 (Median) Methylation in Control 8.84E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg09760889)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:2.53E-07; Z-score:-1.53E+00

Methylation in Case

6.76E-01 (Median) Methylation in Control 7.48E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg17527484)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.89E+00 Statistic Test p-value:2.53E-07; Z-score:1.54E+00

Methylation in Case

2.47E-01 (Median) Methylation in Control 1.31E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg23529278)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.20E+00 Statistic Test p-value:2.03E-06; Z-score:-1.69E+00

Methylation in Case

7.51E-01 (Median) Methylation in Control 9.02E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg25601446)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.08E+00 Statistic Test p-value:1.59E-05; Z-score:-1.10E+00

Methylation in Case

7.12E-01 (Median) Methylation in Control 7.70E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon16

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg18948221)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:2.40E-05; Z-score:-1.25E+00

Methylation in Case

7.46E-01 (Median) Methylation in Control 8.31E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon17

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg09247259)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:4.52E-05; Z-score:-8.69E-01

Methylation in Case

8.86E-01 (Median) Methylation in Control 9.05E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon18

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg17295589)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.07E-04; Z-score:-1.27E+00

Methylation in Case

9.45E-01 (Median) Methylation in Control 9.61E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon19

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg16760172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:1.78E-03; Z-score:-9.53E-01

Methylation in Case

8.27E-01 (Median) Methylation in Control 8.77E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon20

Methylation of SCN4A in breast cancer [ 5 ]

Location

Body (cg21091640)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:9.17E-03; Z-score:-4.63E-01

Methylation in Case

8.99E-01 (Median) Methylation in Control 9.09E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon21

Methylation of SCN4A in breast cancer [ 5 ]

Location

3'UTR (cg01442319)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.17E+00 Statistic Test p-value:1.06E-11; Z-score:1.71E+00

Methylation in Case

7.35E-01 (Median) Methylation in Control 6.28E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon22

Methylation of SCN4A in breast cancer [ 5 ]

Location

3'UTR (cg03917100)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.16E+00 Statistic Test p-value:6.00E-08; Z-score:1.46E+00

Methylation in Case

7.29E-01 (Median) Methylation in Control 6.27E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Colorectal cancer

         18 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:1.17E-06; Z-score:-1.73E+00

Methylation in Case

8.62E-01 (Median) Methylation in Control 8.89E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

TSS200 (cg23722792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:2.62E-05; Z-score:-6.50E-01

Methylation in Case

9.33E-01 (Median) Methylation in Control 9.39E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

TSS200 (cg23387800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.00E+00 Statistic Test p-value:1.30E-02; Z-score:1.00E-01

Methylation in Case

9.06E-01 (Median) Methylation in Control 9.05E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

1stExon (cg13694749)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.17E+00 Statistic Test p-value:8.09E-14; Z-score:-6.41E+00

Methylation in Case

7.68E-01 (Median) Methylation in Control 8.96E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.54E+00 Statistic Test p-value:2.36E-15; Z-score:-2.92E+00

Methylation in Case

4.07E-01 (Median) Methylation in Control 6.27E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg05367173)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.12E+00 Statistic Test p-value:1.96E-10; Z-score:-6.21E+00

Methylation in Case

8.24E-01 (Median) Methylation in Control 9.26E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg25601446)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:9.23E-09; Z-score:-3.29E+00

Methylation in Case

8.25E-01 (Median) Methylation in Control 8.84E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg09760889)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.27E+00 Statistic Test p-value:3.20E-08; Z-score:-2.13E+00

Methylation in Case

5.53E-01 (Median) Methylation in Control 7.03E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg23529278)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:4.42E-08; Z-score:-4.34E+00

Methylation in Case

8.98E-01 (Median) Methylation in Control 9.44E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg18948221)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:9.30E-07; Z-score:-1.91E+00

Methylation in Case

8.78E-01 (Median) Methylation in Control 9.12E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg16760172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:1.60E-06; Z-score:-1.76E+00

Methylation in Case

8.99E-01 (Median) Methylation in Control 9.30E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg26503701)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:2.00E-06; Z-score:-1.97E+00

Methylation in Case

8.87E-01 (Median) Methylation in Control 9.13E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg26840162)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.59E-03; Z-score:-7.94E-01

Methylation in Case

9.38E-01 (Median) Methylation in Control 9.45E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg19881928)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.18E+00 Statistic Test p-value:3.36E-03; Z-score:4.58E-01

Methylation in Case

8.75E-02 (Median) Methylation in Control 7.40E-02 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

Body (cg20433103)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:3.57E-02; Z-score:-3.97E-01

Methylation in Case

9.45E-01 (Median) Methylation in Control 9.49E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon16

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

3'UTR (cg01442319)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:6.14E-05; Z-score:-1.30E+00

Methylation in Case

9.05E-01 (Median) Methylation in Control 9.20E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon17

Methylation of SCN4A in colorectal cancer [ 6 ]

Location

3'UTR (cg03917100)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:9.05E-03; Z-score:-4.51E-01

Methylation in Case

8.97E-01 (Median) Methylation in Control 9.06E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Lung adenocarcinoma

           9 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:2.89E-03; Z-score:-2.17E+00

Methylation in Case

7.59E-01 (Median) Methylation in Control 8.01E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg05367173)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.08E+00 Statistic Test p-value:4.49E-06; Z-score:-3.54E+00

Methylation in Case

8.36E-01 (Median) Methylation in Control 9.02E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.30E+00 Statistic Test p-value:6.65E-05; Z-score:-2.73E+00

Methylation in Case

5.13E-01 (Median) Methylation in Control 6.67E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg17527484)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.24E+00 Statistic Test p-value:1.27E-03; Z-score:-1.71E+00

Methylation in Case

2.93E-01 (Median) Methylation in Control 3.65E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg09760889)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:1.59E-02; Z-score:-2.51E+00

Methylation in Case

7.45E-01 (Median) Methylation in Control 7.93E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg23529278)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.80E-02; Z-score:-9.31E-01

Methylation in Case

8.92E-01 (Median) Methylation in Control 9.09E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg25601446)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:3.44E-02; Z-score:-1.88E+00

Methylation in Case

8.00E-01 (Median) Methylation in Control 8.36E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

Body (cg17295589)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:4.53E-02; Z-score:-1.86E+00

Methylation in Case

9.33E-01 (Median) Methylation in Control 9.41E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in lung adenocarcinoma [ 7 ]

Location

3'UTR (cg01442319)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:2.57E-02; Z-score:-1.27E+00

Methylation in Case

8.49E-01 (Median) Methylation in Control 8.68E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Panic disorder

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in panic disorder [ 8 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:1.83E-02; Z-score:4.79E-01

Methylation in Case

1.45E+00 (Median) Methylation in Control 1.32E+00 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in panic disorder [ 8 ]

Location

Body (cg09247259)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.02E+00 Statistic Test p-value:1.07E-02; Z-score:2.24E-01

Methylation in Case

3.60E+00 (Median) Methylation in Control 3.52E+00 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in panic disorder [ 8 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.13E+00 Statistic Test p-value:2.98E-02; Z-score:3.93E-01

Methylation in Case

1.36E+00 (Median) Methylation in Control 1.21E+00 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Papillary thyroid cancer

           9 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

TSS200 (cg26763542)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.23E-05; Z-score:-9.37E-01

Methylation in Case

8.42E-01 (Median) Methylation in Control 8.60E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

TSS200 (cg22499001)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:6.38E-04; Z-score:-6.63E-01

Methylation in Case

9.09E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

TSS200 (cg23387800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:3.61E-03; Z-score:-7.04E-01

Methylation in Case

8.32E-01 (Median) Methylation in Control 8.46E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

TSS200 (cg23722792)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:6.60E-03; Z-score:-6.94E-01

Methylation in Case

8.83E-01 (Median) Methylation in Control 8.97E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

Body (cg19881928)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.09E+00 Statistic Test p-value:2.01E-03; Z-score:4.99E-01

Methylation in Case

1.34E-01 (Median) Methylation in Control 1.23E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

Body (cg24069602)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:2.64E-03; Z-score:-1.14E+00

Methylation in Case

6.71E-01 (Median) Methylation in Control 7.16E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

Body (cg17527484)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.08E+00 Statistic Test p-value:2.13E-02; Z-score:6.08E-01

Methylation in Case

2.21E-01 (Median) Methylation in Control 2.04E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

Body (cg09247259)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:2.74E-02; Z-score:-5.62E-01

Methylation in Case

9.49E-01 (Median) Methylation in Control 9.55E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SCN4A in papillary thyroid cancer [ 9 ]

Location

Body (cg18948221)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:4.24E-02; Z-score:-1.40E-02

Methylation in Case

9.05E-01 (Median) Methylation in Control 9.05E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Renal cell carcinoma

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in clear cell renal cell carcinoma [ 10 ]

Location

Body (cg18948221)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:8.12E-05; Z-score:-1.78E+00

Methylation in Case

9.53E-01 (Median) Methylation in Control 9.64E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in clear cell renal cell carcinoma [ 10 ]

Location

Body (cg23529278)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:3.39E-04; Z-score:-1.84E+00

Methylation in Case

9.78E-01 (Median) Methylation in Control 9.83E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in clear cell renal cell carcinoma [ 10 ]

Location

Body (cg26840162)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.73E-03; Z-score:-1.21E+00

Methylation in Case

9.70E-01 (Median) Methylation in Control 9.75E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Colon cancer

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SCN4A in colon adenocarcinoma [ 11 ]

Location

Body (cg19112204)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.15E+00 Statistic Test p-value:2.85E-05; Z-score:-3.07E+00

Methylation in Case

6.82E-01 (Median) Methylation in Control 7.82E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SCN4A in colon adenocarcinoma [ 11 ]

Location

Body (cg06708198)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:8.19E-05; Z-score:-1.66E+00

Methylation in Case

8.68E-01 (Median) Methylation in Control 8.94E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SCN4A in colon adenocarcinoma [ 11 ]

Location

Body (cg23260105)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:3.10E-04; Z-score:-3.44E+00

Methylation in Case

9.26E-01 (Median) Methylation in Control 9.74E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples
References
1 Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
2 Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
3 Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
4 DNA Methylation Dynamics in Urological Tumors.
5 Genome-wide Scan for Methylation Profiles in Breast Cancer
6 Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
7 DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
8 DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
9 Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
10 A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
11 Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.

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