Detail Information of Epigenetic Regulations

General Information of Drug Transporter (DT)
DT ID DTD0246 Transporter Info
Gene Name SLC28A3
Transporter Name Concentrative Na(+)-nucleoside cotransporter 3
Gene ID
64078
UniProt ID
Q9HAS3
Epigenetic Regulations of This DT (EGR)

Methylation

  Atypical teratoid rhabdoid tumor

            3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in atypical teratoid rhabdoid tumor [ 1 ]

Location

 5'UTR (cg14000856)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.14E+00 Statistic Test p-value:7.33E-07; Z-score:9.31E-01

Methylation in Case

 8.89E-01 (Median) Methylation in Control 7.78E-01 (Median)

Studied Phenotype

 Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in atypical teratoid rhabdoid tumor [ 1 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.08E+00 Statistic Test p-value:3.93E-02; Z-score:3.83E-01

Methylation in Case

 2.37E-01 (Median) Methylation in Control 2.20E-01 (Median)

Studied Phenotype

 Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in atypical teratoid rhabdoid tumor [ 1 ]

Location

 Body (cg14441891)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.16E+00 Statistic Test p-value:4.65E-02; Z-score:-3.66E-01

Methylation in Case

 2.95E-01 (Median) Methylation in Control 3.43E-01 (Median)

Studied Phenotype

 Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

 Patient tissue samples

  Bladder cancer

            4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in bladder cancer [ 2 ]

Location

 5'UTR (cg14000856)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.13E+00 Statistic Test p-value:1.41E-02; Z-score:-1.91E+00

Methylation in Case

 6.88E-01 (Median) Methylation in Control 7.79E-01 (Median)

Studied Phenotype

 Bladder cancer[ ICD-11:2C94]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in bladder cancer [ 2 ]

Location

 TSS1500 (cg13768445)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.06E+00 Statistic Test p-value:1.91E-04; Z-score:-3.72E+00

Methylation in Case

 7.88E-01 (Median) Methylation in Control 8.38E-01 (Median)

Studied Phenotype

 Bladder cancer[ ICD-11:2C94]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in bladder cancer [ 2 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.05E+00 Statistic Test p-value:2.41E-02; Z-score:-1.12E+00

Methylation in Case

 6.53E-01 (Median) Methylation in Control 6.87E-01 (Median)

Studied Phenotype

 Bladder cancer[ ICD-11:2C94]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in bladder cancer [ 2 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.20E+00 Statistic Test p-value:1.38E-06; Z-score:-8.01E+00

Methylation in Case

 7.01E-01 (Median) Methylation in Control 8.38E-01 (Median)

Studied Phenotype

 Bladder cancer[ ICD-11:2C94]

Experimental Material

 Patient tissue samples

  Breast cancer

            5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in breast cancer [ 3 ]

Location

 5'UTR (cg14000856)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.12E+00 Statistic Test p-value:1.21E-03; Z-score:-7.95E-01

Methylation in Case

 7.32E-01 (Median) Methylation in Control 8.17E-01 (Median)

Studied Phenotype

 Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in breast cancer [ 3 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.16E+00 Statistic Test p-value:4.08E-13; Z-score:1.82E+00

Methylation in Case

 6.22E-01 (Median) Methylation in Control 5.34E-01 (Median)

Studied Phenotype

 Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in breast cancer [ 3 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.06E+00 Statistic Test p-value:1.05E-07; Z-score:-1.32E+00

Methylation in Case

 8.06E-01 (Median) Methylation in Control 8.57E-01 (Median)

Studied Phenotype

 Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in breast cancer [ 3 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.38E+00 Statistic Test p-value:5.08E-07; Z-score:1.30E+00

Methylation in Case

 2.26E-01 (Median) Methylation in Control 1.64E-01 (Median)

Studied Phenotype

 Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon5

 Methylation of SLC28A3 in breast cancer [ 3 ]

Location

 Body (cg14441891)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.01E+00 Statistic Test p-value:2.09E-04; Z-score:-7.51E-01

Methylation in Case

 9.20E-01 (Median) Methylation in Control 9.34E-01 (Median)

Studied Phenotype

 Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

 Patient tissue samples

  Colorectal cancer

            6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in colorectal cancer [ 4 ]

Location

 5'UTR (cg14000856)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.02E+00 Statistic Test p-value:2.61E-03; Z-score:-6.95E-01

Methylation in Case

 8.58E-01 (Median) Methylation in Control 8.79E-01 (Median)

Studied Phenotype

 Colorectal cancer[ ICD-11:2B91]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in colorectal cancer [ 4 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.06E+00 Statistic Test p-value:1.05E-07; Z-score:-1.68E+00

Methylation in Case

 8.20E-01 (Median) Methylation in Control 8.65E-01 (Median)

Studied Phenotype

 Colorectal cancer[ ICD-11:2B91]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in colorectal cancer [ 4 ]

Location

 TSS1500 (cg13768445)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.00E+00 Statistic Test p-value:4.27E-02; Z-score:-8.83E-02

Methylation in Case

 8.24E-01 (Median) Methylation in Control 8.26E-01 (Median)

Studied Phenotype

 Colorectal cancer[ ICD-11:2B91]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in colorectal cancer [ 4 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.04E+00 Statistic Test p-value:8.88E-08; Z-score:-2.03E+00

Methylation in Case

 8.68E-01 (Median) Methylation in Control 9.03E-01 (Median)

Studied Phenotype

 Colorectal cancer[ ICD-11:2B91]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon5

 Methylation of SLC28A3 in colorectal cancer [ 4 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.10E+00 Statistic Test p-value:4.35E-03; Z-score:5.23E-01

Methylation in Case

 4.22E-01 (Median) Methylation in Control 3.84E-01 (Median)

Studied Phenotype

 Colorectal cancer[ ICD-11:2B91]

Experimental Material

 Patient tissue samples

  HIV infection

            5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in HIV infection [ 5 ]

Location

 5'UTR (cg14000856)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.08E+00 Statistic Test p-value:2.35E-03; Z-score:-1.09E+00

Methylation in Case

 7.23E-01 (Median) Methylation in Control 7.81E-01 (Median)

Studied Phenotype

 HIV infection[ ICD-11:1C62.Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in HIV infection [ 5 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.18E+00 Statistic Test p-value:1.92E-13; Z-score:2.56E+00

Methylation in Case

 7.04E-01 (Median) Methylation in Control 5.96E-01 (Median)

Studied Phenotype

 HIV infection[ ICD-11:1C62.Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in HIV infection [ 5 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.09E+00 Statistic Test p-value:2.15E-13; Z-score:1.24E+00

Methylation in Case

 8.27E-01 (Median) Methylation in Control 7.56E-01 (Median)

Studied Phenotype

 HIV infection[ ICD-11:1C62.Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in HIV infection [ 5 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.16E+00 Statistic Test p-value:1.04E-05; Z-score:1.19E+00

Methylation in Case

 4.52E-01 (Median) Methylation in Control 3.91E-01 (Median)

Studied Phenotype

 HIV infection[ ICD-11:1C62.Z]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon5

 Methylation of SLC28A3 in HIV infection [ 5 ]

Location

 Body (cg14441891)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.01E+00 Statistic Test p-value:1.55E-02; Z-score:-6.64E-01

Methylation in Case

 9.58E-01 (Median) Methylation in Control 9.70E-01 (Median)

Studied Phenotype

 HIV infection[ ICD-11:1C62.Z]

Experimental Material

 Patient tissue samples

  Pancretic ductal adenocarcinoma

            4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in pancretic ductal adenocarcinoma [ 6 ]

Location

 5'UTR (cg15947599)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.02E+00 Statistic Test p-value:8.12E-05; Z-score:1.01E+00

Methylation in Case

 8.87E-01 (Median) Methylation in Control 8.72E-01 (Median)

Studied Phenotype

 Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in pancretic ductal adenocarcinoma [ 6 ]

Location

 TSS1500 (cg27520549)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.04E+00 Statistic Test p-value:4.01E-06; Z-score:-7.55E-01

Methylation in Case

 7.12E-01 (Median) Methylation in Control 7.42E-01 (Median)

Studied Phenotype

 Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in pancretic ductal adenocarcinoma [ 6 ]

Location

 Body (cg02881274)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.39E+00 Statistic Test p-value:8.94E-28; Z-score:4.79E+00

Methylation in Case

 5.29E-01 (Median) Methylation in Control 3.81E-01 (Median)

Studied Phenotype

 Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in pancretic ductal adenocarcinoma [ 6 ]

Location

 Body (cg09173378)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.70E+00 Statistic Test p-value:1.41E-15; Z-score:-2.88E+00

Methylation in Case

 4.30E-01 (Median) Methylation in Control 7.32E-01 (Median)

Studied Phenotype

 Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

 Patient tissue samples

  Hepatocellular carcinoma

            6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 TSS1500 (cg13768445)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.13E+00 Statistic Test p-value:1.90E-09; Z-score:-1.53E+00

Methylation in Case

 7.14E-01 (Median) Methylation in Control 8.07E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.14E+00 Statistic Test p-value:9.85E-09; Z-score:-2.58E+00

Methylation in Case

 6.76E-01 (Median) Methylation in Control 7.73E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.13E+00 Statistic Test p-value:2.16E-09; Z-score:-3.22E+00

Methylation in Case

 7.16E-01 (Median) Methylation in Control 8.13E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon4

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 Body (cg05036153)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.33E+00 Statistic Test p-value:1.29E-12; Z-score:-1.97E+00

Methylation in Case

 2.87E-01 (Median) Methylation in Control 3.82E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon5

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.24E+00 Statistic Test p-value:4.63E-04; Z-score:-9.43E-01

Methylation in Case

 1.93E-01 (Median) Methylation in Control 2.39E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon6

 Methylation of SLC28A3 in hepatocellular carcinoma [ 7 ]

Location

 3'UTR (cg10097316)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.28E+00 Statistic Test p-value:3.02E-12; Z-score:-3.70E+00

Methylation in Case

 5.77E-01 (Median) Methylation in Control 7.37E-01 (Median)

Studied Phenotype

 Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

 Patient tissue samples

  Lung adenocarcinoma

            2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in lung adenocarcinoma [ 8 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.08E+00 Statistic Test p-value:2.19E-02; Z-score:-3.07E+00

Methylation in Case

 6.87E-01 (Median) Methylation in Control 7.39E-01 (Median)

Studied Phenotype

 Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in lung adenocarcinoma [ 8 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.31E+00 Statistic Test p-value:2.49E-02; Z-score:2.26E+00

Methylation in Case

 3.47E-01 (Median) Methylation in Control 2.64E-01 (Median)

Studied Phenotype

 Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

 Patient tissue samples

  Papillary thyroid cancer

            3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in papillary thyroid cancer [ 9 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.04E+00 Statistic Test p-value:1.35E-05; Z-score:-9.17E-01

Methylation in Case

 7.95E-01 (Median) Methylation in Control 8.23E-01 (Median)

Studied Phenotype

 Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in papillary thyroid cancer [ 9 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.01E+00 Statistic Test p-value:5.71E-03; Z-score:-3.73E-01

Methylation in Case

 9.03E-01 (Median) Methylation in Control 9.11E-01 (Median)

Studied Phenotype

 Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon3

 Methylation of SLC28A3 in papillary thyroid cancer [ 9 ]

Location

 Body (cg13837033)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.05E+00 Statistic Test p-value:1.37E-02; Z-score:2.61E-01

Methylation in Case

 1.94E-01 (Median) Methylation in Control 1.85E-01 (Median)

Studied Phenotype

 Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

 Patient tissue samples

  Systemic lupus erythematosus

            2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in systemic lupus erythematosus [ 10 ]

Location

 TSS1500 (cg21190895)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.02E+00 Statistic Test p-value:4.55E-02; Z-score:-2.97E-01

Methylation in Case

 7.75E-01 (Median) Methylation in Control 7.92E-01 (Median)

Studied Phenotype

 Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

 Patient tissue samples

  Epigenetic Phenomenon2

 Methylation of SLC28A3 in systemic lupus erythematosus [ 10 ]

Location

 TSS200 (cg23059452)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:-1.02E+00 Statistic Test p-value:8.09E-03; Z-score:-2.95E-01

Methylation in Case

 8.31E-01 (Median) Methylation in Control 8.47E-01 (Median)

Studied Phenotype

 Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

 Patient tissue samples

  Prostate cancer

            2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

 Methylation of SLC28A3 in prostate cancer [ 11 ]

Location

 TSS200 (cg12824106)

Epigenetic Type

 Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

 Fold Change:1.58E+00 Statistic Test p-value:1.28E-02; Z-score:3.04E+00

Methylation in Case

 1.75E-02 (Median) Methylation in Control 1.11E-02 (Median)

Studied Phenotype

 Prostate cancer[ ICD-11:2C82]

Experimental Material

 Patient tissue samples
References
1 Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
2 DNA Methylation Dynamics in Urological Tumors.
3 Genome-wide Scan for Methylation Profiles in Breast Cancer
4 Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
5 HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
6 Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
7 Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
8 DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
9 Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
10 Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9(8):e1003678.
11 Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.

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