General Information of Drug Transporter (DT)
DT ID DTD0190 Transporter Info
Gene Name SLC25A29
Transporter Name Mitochondrial ornithine transporter 3
Gene ID
123096
UniProt ID
Q8N8R3
Epigenetic Regulations of This DT (EGR)

Methylation

  Pancretic ductal adenocarcinoma

           5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in pancretic ductal adenocarcinoma [ 1 ]

Location

TSS1500 (cg18710929)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.32E+00 Statistic Test p-value:2.75E-25; Z-score:6.45E+00

Methylation in Case

2.25E-01 (Median) Methylation in Control 9.69E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in pancretic ductal adenocarcinoma [ 1 ]

Location

Body (cg04012082)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.51E+00 Statistic Test p-value:2.69E-15; Z-score:-2.53E+00

Methylation in Case

2.68E-01 (Median) Methylation in Control 4.05E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in pancretic ductal adenocarcinoma [ 1 ]

Location

Body (cg15175242)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:4.15E-08; Z-score:-6.42E-01

Methylation in Case

8.53E-01 (Median) Methylation in Control 8.68E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in pancretic ductal adenocarcinoma [ 1 ]

Location

Body (cg01740650)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:3.89E-03; Z-score:-2.84E-01

Methylation in Case

8.91E-01 (Median) Methylation in Control 8.96E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in pancretic ductal adenocarcinoma [ 1 ]

Location

Body (cg10786489)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:3.46E-02; Z-score:-2.83E-01

Methylation in Case

8.36E-01 (Median) Methylation in Control 8.41E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Hepatocellular carcinoma

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

TSS200 (cg04299028)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.73E+00 Statistic Test p-value:1.44E-18; Z-score:-5.34E+00

Methylation in Case

4.03E-01 (Median) Methylation in Control 6.98E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

TSS200 (cg21306329)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.45E+00 Statistic Test p-value:5.49E-15; Z-score:1.83E+00

Methylation in Case

6.34E-01 (Median) Methylation in Control 4.39E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.18E+00 Statistic Test p-value:2.66E-06; Z-score:1.36E+00

Methylation in Case

5.55E-01 (Median) Methylation in Control 4.70E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:1.21E-03; Z-score:-3.37E-01

Methylation in Case

7.01E-01 (Median) Methylation in Control 7.17E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.09E+00 Statistic Test p-value:3.50E-02; Z-score:8.91E-01

Methylation in Case

6.67E-01 (Median) Methylation in Control 6.13E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC25A29 in hepatocellular carcinoma [ 2 ]

Location

3'UTR (cg20929849)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:2.72E-05; Z-score:-1.37E+00

Methylation in Case

8.12E-01 (Median) Methylation in Control 8.47E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Prostate cancer

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in prostate cancer [ 3 ]

Location

TSS200 (cg21977075)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.53E+00 Statistic Test p-value:1.82E-02; Z-score:2.44E+00

Methylation in Case

7.37E-01 (Median) Methylation in Control 4.82E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in prostate cancer [ 3 ]

Location

Body (cg20955989)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.57E+00 Statistic Test p-value:3.80E-02; Z-score:6.49E+00

Methylation in Case

5.17E-01 (Median) Methylation in Control 2.01E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in prostate cancer [ 3 ]

Location

3'UTR (cg07501827)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.13E+00 Statistic Test p-value:1.54E-03; Z-score:3.61E+00

Methylation in Case

8.49E-01 (Median) Methylation in Control 7.50E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Colon cancer

           5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in colon adenocarcinoma [ 4 ]

Location

1stExon (cg12348970)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:2.56E-03; Z-score:-2.60E+00

Methylation in Case

8.05E-01 (Median) Methylation in Control 8.56E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in colon adenocarcinoma [ 4 ]

Location

Body (cg13960084)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.97E+00 Statistic Test p-value:2.03E-07; Z-score:6.58E+00

Methylation in Case

4.48E-01 (Median) Methylation in Control 1.51E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in colon adenocarcinoma [ 4 ]

Location

Body (cg07489029)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.07E+00 Statistic Test p-value:8.61E-04; Z-score:-2.12E+00

Methylation in Case

8.11E-01 (Median) Methylation in Control 8.70E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in colon adenocarcinoma [ 4 ]

Location

Body (cg11828251)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.12E+00 Statistic Test p-value:1.97E-03; Z-score:-2.53E+00

Methylation in Case

7.04E-01 (Median) Methylation in Control 7.86E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in colon adenocarcinoma [ 4 ]

Location

Body (cg12096528)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:2.46E-03; Z-score:-1.11E+00

Methylation in Case

8.23E-01 (Median) Methylation in Control 8.45E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Atypical teratoid rhabdoid tumor

           8 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg01437482)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.08E+00 Statistic Test p-value:6.81E-05; Z-score:5.98E-01

Methylation in Case

8.74E-01 (Median) Methylation in Control 8.12E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.17E+00 Statistic Test p-value:7.33E-05; Z-score:-1.08E+00

Methylation in Case

6.31E-01 (Median) Methylation in Control 7.35E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg03886017)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.21E+00 Statistic Test p-value:4.60E-04; Z-score:-7.63E-01

Methylation in Case

5.82E-01 (Median) Methylation in Control 7.04E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg05043627)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:1.22E-03; Z-score:-5.53E-01

Methylation in Case

8.19E-01 (Median) Methylation in Control 8.43E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:4.24E-02; Z-score:3.19E-01

Methylation in Case

9.04E-01 (Median) Methylation in Control 8.80E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

Body (cg14318489)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:4.49E-02; Z-score:-7.96E-02

Methylation in Case

4.17E-02 (Median) Methylation in Control 4.36E-02 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

3'UTR (cg15862841)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:6.67E-11; Z-score:-1.64E+00

Methylation in Case

8.30E-01 (Median) Methylation in Control 8.67E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC25A29 in atypical teratoid rhabdoid tumor [ 5 ]

Location

3'UTR (cg20929849)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.24E+00 Statistic Test p-value:4.82E-10; Z-score:1.90E+00

Methylation in Case

8.37E-01 (Median) Methylation in Control 6.73E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Bladder cancer

           9 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.42E+00 Statistic Test p-value:2.96E-08; Z-score:7.27E+00

Methylation in Case

4.98E-01 (Median) Methylation in Control 2.06E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.43E+00 Statistic Test p-value:5.11E-08; Z-score:-9.23E+00

Methylation in Case

5.59E-01 (Median) Methylation in Control 8.01E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg05043627)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.87E+00 Statistic Test p-value:9.76E-06; Z-score:-4.45E+00

Methylation in Case

1.06E-01 (Median) Methylation in Control 1.98E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.23E+00 Statistic Test p-value:2.38E-04; Z-score:-3.44E+00

Methylation in Case

4.28E-01 (Median) Methylation in Control 5.26E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg17705681)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.03E+00 Statistic Test p-value:2.60E-04; Z-score:-7.45E+00

Methylation in Case

8.93E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg18804587)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:6.03E-03; Z-score:2.15E+00

Methylation in Case

9.51E-01 (Median) Methylation in Control 9.26E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg24141378)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:2.07E-02; Z-score:-1.57E+00

Methylation in Case

8.22E-01 (Median) Methylation in Control 8.38E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

Body (cg25906332)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.18E+00 Statistic Test p-value:2.58E-02; Z-score:-1.67E+00

Methylation in Case

5.08E-02 (Median) Methylation in Control 5.99E-02 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SLC25A29 in bladder cancer [ 6 ]

Location

3'UTR (cg20929849)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:4.07E-02; Z-score:-1.25E+00

Methylation in Case

8.11E-01 (Median) Methylation in Control 8.26E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Breast cancer

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.12E+00 Statistic Test p-value:1.44E-11; Z-score:-2.56E+00

Methylation in Case

7.04E-01 (Median) Methylation in Control 7.86E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

Body (cg05043627)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.49E+00 Statistic Test p-value:6.34E-09; Z-score:-1.62E+00

Methylation in Case

1.21E-01 (Median) Methylation in Control 1.79E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.20E+00 Statistic Test p-value:1.20E-07; Z-score:1.72E+00

Methylation in Case

2.75E-01 (Median) Methylation in Control 2.28E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.12E+00 Statistic Test p-value:5.62E-07; Z-score:-1.23E+00

Methylation in Case

4.86E-01 (Median) Methylation in Control 5.44E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.33E+00 Statistic Test p-value:2.88E-05; Z-score:1.14E+00

Methylation in Case

1.87E-01 (Median) Methylation in Control 1.40E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC25A29 in breast cancer [ 7 ]

Location

3'UTR (cg20929849)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.06E+00 Statistic Test p-value:1.49E-02; Z-score:1.66E+00

Methylation in Case

8.44E-01 (Median) Methylation in Control 7.96E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Renal cell carcinoma

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.08E+00 Statistic Test p-value:1.40E-08; Z-score:2.06E+00

Methylation in Case

2.16E-01 (Median) Methylation in Control 1.04E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg20299151)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:5.49E-03; Z-score:-5.59E-01

Methylation in Case

9.81E-01 (Median) Methylation in Control 9.82E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.09E+00 Statistic Test p-value:1.26E-02; Z-score:-1.11E+00

Methylation in Case

5.87E-01 (Median) Methylation in Control 6.41E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg24141378)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:1.70E-02; Z-score:-2.89E-01

Methylation in Case

9.41E-01 (Median) Methylation in Control 9.44E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg14318489)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:1.79E-02; Z-score:-1.52E-01

Methylation in Case

9.81E-01 (Median) Methylation in Control 9.81E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC25A29 in clear cell renal cell carcinoma [ 8 ]

Location

Body (cg17705681)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:4.86E-02; Z-score:-3.68E-01

Methylation in Case

9.74E-01 (Median) Methylation in Control 9.76E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Colorectal cancer

           5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in colorectal cancer [ 9 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.14E+00 Statistic Test p-value:1.34E-10; Z-score:-4.00E+00

Methylation in Case

7.56E-01 (Median) Methylation in Control 8.59E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in colorectal cancer [ 9 ]

Location

Body (cg14318489)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:1.81E-04; Z-score:-1.16E+00

Methylation in Case

9.76E-01 (Median) Methylation in Control 9.79E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in colorectal cancer [ 9 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.17E+00 Statistic Test p-value:6.80E-04; Z-score:1.28E+00

Methylation in Case

7.01E-01 (Median) Methylation in Control 5.99E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in colorectal cancer [ 9 ]

Location

Body (cg24141378)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:1.64E-02; Z-score:-9.23E-02

Methylation in Case

9.31E-01 (Median) Methylation in Control 9.32E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in colorectal cancer [ 9 ]

Location

Body (cg16073846)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.24E+00 Statistic Test p-value:2.40E-02; Z-score:-5.63E-01

Methylation in Case

1.89E-02 (Median) Methylation in Control 2.36E-02 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Depression

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in depression [ 10 ]

Location

Body (cg18804587)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.01E+00 Statistic Test p-value:1.62E-02; Z-score:3.54E-01

Methylation in Case

9.18E-01 (Median) Methylation in Control 9.12E-01 (Median)

Studied Phenotype

Depression[ ICD-11:6A8Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in depression [ 10 ]

Location

Body (cg14318489)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:2.19E-02; Z-score:-4.23E-01

Methylation in Case

9.48E-01 (Median) Methylation in Control 9.51E-01 (Median)

Studied Phenotype

Depression[ ICD-11:6A8Z]

Experimental Material

Patient tissue samples

  HIV infection

           5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in HIV infection [ 11 ]

Location

Body (cg14064024)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.28E+00 Statistic Test p-value:8.69E-10; Z-score:2.10E+00

Methylation in Case

5.65E-01 (Median) Methylation in Control 4.42E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in HIV infection [ 11 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.53E+00 Statistic Test p-value:2.86E-07; Z-score:1.82E+00

Methylation in Case

3.10E-01 (Median) Methylation in Control 2.03E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in HIV infection [ 11 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.39E+00 Statistic Test p-value:1.11E-05; Z-score:2.36E+00

Methylation in Case

3.22E-01 (Median) Methylation in Control 2.31E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in HIV infection [ 11 ]

Location

Body (cg18804587)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.01E+00 Statistic Test p-value:5.48E-05; Z-score:5.78E-01

Methylation in Case

9.62E-01 (Median) Methylation in Control 9.55E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in HIV infection [ 11 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.08E+00 Statistic Test p-value:2.61E-04; Z-score:-1.51E+00

Methylation in Case

7.59E-01 (Median) Methylation in Control 8.23E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Lung adenocarcinoma

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in lung adenocarcinoma [ 12 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.09E+00 Statistic Test p-value:3.11E-04; Z-score:-2.65E+00

Methylation in Case

7.74E-01 (Median) Methylation in Control 8.45E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in lung adenocarcinoma [ 12 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.52E+00 Statistic Test p-value:3.51E-03; Z-score:2.70E+00

Methylation in Case

3.68E-01 (Median) Methylation in Control 2.43E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in lung adenocarcinoma [ 12 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.26E+00 Statistic Test p-value:1.08E-02; Z-score:1.98E+00

Methylation in Case

2.76E-01 (Median) Methylation in Control 2.20E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Panic disorder

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in panic disorder [ 13 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.15E+00 Statistic Test p-value:6.00E-03; Z-score:6.11E-01

Methylation in Case

2.25E+00 (Median) Methylation in Control 1.95E+00 (Median)

Studied Phenotype

Panic disorder[ ICD-11:6B01]

Experimental Material

Patient tissue samples

  Papillary thyroid cancer

           5 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in papillary thyroid cancer [ 14 ]

Location

Body (cg23709172)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.15E+00 Statistic Test p-value:8.51E-05; Z-score:7.94E-01

Methylation in Case

1.65E-01 (Median) Methylation in Control 1.43E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in papillary thyroid cancer [ 14 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.21E+00 Statistic Test p-value:1.56E-03; Z-score:6.29E-01

Methylation in Case

1.25E-01 (Median) Methylation in Control 1.04E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in papillary thyroid cancer [ 14 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:2.76E-02; Z-score:-9.06E-02

Methylation in Case

7.96E-01 (Median) Methylation in Control 8.00E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC25A29 in papillary thyroid cancer [ 14 ]

Location

Body (cg18804587)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.00E+00 Statistic Test p-value:4.27E-02; Z-score:1.82E-01

Methylation in Case

9.27E-01 (Median) Methylation in Control 9.25E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC25A29 in papillary thyroid cancer [ 14 ]

Location

3'UTR (cg15862841)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:1.32E-11; Z-score:1.64E+00

Methylation in Case

9.32E-01 (Median) Methylation in Control 8.70E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Systemic lupus erythematosus

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC25A29 in systemic lupus erythematosus [ 15 ]

Location

Body (cg18629527)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:1.47E-02; Z-score:1.68E-01

Methylation in Case

3.03E-01 (Median) Methylation in Control 2.84E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC25A29 in systemic lupus erythematosus [ 15 ]

Location

Body (cg03886017)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:2.98E-02; Z-score:-3.20E-02

Methylation in Case

9.27E-01 (Median) Methylation in Control 9.28E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC25A29 in systemic lupus erythematosus [ 15 ]

Location

Body (cg01551177)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:3.70E-02; Z-score:-2.73E-01

Methylation in Case

7.68E-01 (Median) Methylation in Control 8.01E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

microRNA

  Unclear Phenotype

           4 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

miR-15a directly targets SLC25A29 [ 16 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-15a miRNA Mature ID miR-15a-5p

miRNA Sequence

UAGCAGCACAUAAUGGUUUGUG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon2

miR-15b directly targets SLC25A29 [ 16 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-15b miRNA Mature ID miR-15b-5p

miRNA Sequence

UAGCAGCACAUCAUGGUUUACA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon3

miR-16 directly targets SLC25A29 [ 16 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-16 miRNA Mature ID miR-16-5p

miRNA Sequence

UAGCAGCACGUAAAUAUUGGCG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon4

miR-195 directly targets SLC25A29 [ 16 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-195 miRNA Mature ID miR-195-5p

miRNA Sequence

UAGCAGCACAGAAAUAUUGGC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human
References
1 Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
2 Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
3 Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
4 Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
5 Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
6 DNA Methylation Dynamics in Urological Tumors.
7 Genome-wide Scan for Methylation Profiles in Breast Cancer
8 A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
9 Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
10 DNA methylation and inflammation marker profiles associated with a history of depression. Hum Mol Genet. 2018 Aug 15;27(16):2840-2850.
11 HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
12 DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
13 DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
14 Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
15 Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9(8):e1003678.
16 EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. EMBO J. 2012 May 2;31(9):2207-21.

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