Detail Information of Epigenetic Regulations

General Information of Drug Transporter (DT)
DT ID	DTD0145 Transporter Info
Gene Name	SLC22A20
Transporter Name	Organic anion transporter 6
Gene ID	440044
UniProt ID	A6NK97

Epigenetic Regulations of This DT (EGR)
Methylation
Pancretic ductal adenocarcinoma	7 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	5'UTR (cg13952688)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.07E+00	Statistic Test	p-value:1.03E-03; Z-score:1.00E+00
Methylation in Case	6.23E-01 (Median)	Methylation in Control	5.84E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	TSS200 (cg11896345)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.05E+00	Statistic Test	p-value:8.08E-03; Z-score:-2.22E-01
Methylation in Case	7.61E-02 (Median)	Methylation in Control	7.98E-02 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	1stExon (cg13649728)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.03E+00	Statistic Test	p-value:2.23E-03; Z-score:6.01E-01
Methylation in Case	8.65E-01 (Median)	Methylation in Control	8.37E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg18836626)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.11E+00	Statistic Test	p-value:1.89E-11; Z-score:2.22E+00
Methylation in Case	4.53E-01 (Median)	Methylation in Control	2.15E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg00601711)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.35E+00	Statistic Test	p-value:6.49E-10; Z-score:2.05E+00
Methylation in Case	7.50E-01 (Median)	Methylation in Control	5.55E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg11609462)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:2.48E-03; Z-score:-5.51E-01
Methylation in Case	8.53E-01 (Median)	Methylation in Control	8.67E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC22A20 in pancretic ductal adenocarcinoma			[ 1 ]
Location	Body (cg24041118)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.20E+00	Statistic Test	p-value:3.48E-02; Z-score:-9.23E-01
Methylation in Case	6.77E-01 (Median)	Methylation in Control	8.10E-01 (Median)
Studied Phenotype	Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]
Experimental Material	Patient tissue samples
Prostate cancer	6 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	5'UTR (cg22855020)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.13E+00	Statistic Test	p-value:3.36E-04; Z-score:6.35E+00
Methylation in Case	7.78E-01 (Median)	Methylation in Control	3.65E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	TSS1500 (cg19313402)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.15E+00	Statistic Test	p-value:2.14E-02; Z-score:1.56E+00
Methylation in Case	8.42E-01 (Median)	Methylation in Control	7.34E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	TSS200 (cg25307593)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.45E+00	Statistic Test	p-value:3.28E-02; Z-score:-2.07E+00
Methylation in Case	2.07E-02 (Median)	Methylation in Control	3.02E-02 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	TSS200 (cg22988581)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.18E+00	Statistic Test	p-value:4.21E-02; Z-score:1.91E+00
Methylation in Case	3.89E-01 (Median)	Methylation in Control	3.31E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	Body (cg14486338)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.83E+00	Statistic Test	p-value:1.86E-02; Z-score:1.98E+00
Methylation in Case	6.66E-01 (Median)	Methylation in Control	3.64E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in prostate cancer			[ 2 ]
Location	Body (cg21172944)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.04E+00	Statistic Test	p-value:2.13E-02; Z-score:2.87E+00
Methylation in Case	8.83E-01 (Median)	Methylation in Control	8.49E-01 (Median)
Studied Phenotype	Prostate cancer[ ICD-11:2C82]
Experimental Material	Patient tissue samples
Bladder cancer	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in bladder cancer			[ 3 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.48E+00	Statistic Test	p-value:1.78E-05; Z-score:-5.04E+00
Methylation in Case	3.87E-01 (Median)	Methylation in Control	5.72E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in bladder cancer			[ 3 ]
Location	TSS1500 (cg03219657)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.81E+00	Statistic Test	p-value:3.19E-04; Z-score:-4.03E+00
Methylation in Case	1.63E-01 (Median)	Methylation in Control	2.95E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in bladder cancer			[ 3 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.24E+00	Statistic Test	p-value:1.51E-03; Z-score:-4.19E+00
Methylation in Case	3.91E-01 (Median)	Methylation in Control	4.83E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in bladder cancer			[ 3 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.19E+00	Statistic Test	p-value:1.00E-03; Z-score:3.90E+00
Methylation in Case	5.60E-01 (Median)	Methylation in Control	4.73E-01 (Median)
Studied Phenotype	Bladder cancer[ ICD-11:2C94]
Experimental Material	Patient tissue samples
Breast cancer	11 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	TSS1500 (cg02707152)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.10E+00	Statistic Test	p-value:5.68E-03; Z-score:7.43E-01
Methylation in Case	3.46E-01 (Median)	Methylation in Control	3.16E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.15E+00	Statistic Test	p-value:1.06E-02; Z-score:-9.00E-01
Methylation in Case	5.99E-01 (Median)	Methylation in Control	6.85E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	TSS200 (cg21080921)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.17E+00	Statistic Test	p-value:2.96E-06; Z-score:-1.67E+00
Methylation in Case	4.36E-01 (Median)	Methylation in Control	5.10E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.19E+00	Statistic Test	p-value:6.61E-06; Z-score:-1.59E+00
Methylation in Case	5.67E-01 (Median)	Methylation in Control	6.74E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	TSS200 (cg14373018)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.13E+00	Statistic Test	p-value:1.14E-02; Z-score:-9.17E-01
Methylation in Case	5.40E-01 (Median)	Methylation in Control	6.08E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.11E+00	Statistic Test	p-value:2.31E-02; Z-score:-1.13E+00
Methylation in Case	5.26E-01 (Median)	Methylation in Control	5.84E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	Body (cg08234507)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.08E+00	Statistic Test	p-value:1.56E-11; Z-score:-2.30E+00
Methylation in Case	7.86E-01 (Median)	Methylation in Control	8.51E-01 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	Body (cg23930334)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:4.67E+00	Statistic Test	p-value:5.65E-11; Z-score:2.93E+00
Methylation in Case	2.15E-01 (Median)	Methylation in Control	4.61E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.89E+00	Statistic Test	p-value:5.82E-11; Z-score:3.50E+00
Methylation in Case	1.61E-01 (Median)	Methylation in Control	5.55E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	Body (cg02675946)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.62E+00	Statistic Test	p-value:2.18E-09; Z-score:2.48E+00
Methylation in Case	1.33E-01 (Median)	Methylation in Control	8.17E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon11	Methylation of SLC22A20 in breast cancer			[ 4 ]
Location	Body (cg27428304)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.73E+00	Statistic Test	p-value:1.55E-08; Z-score:2.22E+00
Methylation in Case	9.97E-02 (Median)	Methylation in Control	5.77E-02 (Median)
Studied Phenotype	Breast cancer[ ICD-11:2C60-2C6Z]
Experimental Material	Patient tissue samples
Colorectal cancer	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in colorectal cancer			[ 5 ]
Location	TSS1500 (cg03219657)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.22E+00	Statistic Test	p-value:8.23E-07; Z-score:-1.23E+00
Methylation in Case	4.78E-01 (Median)	Methylation in Control	5.82E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in colorectal cancer			[ 5 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.09E+00	Statistic Test	p-value:4.33E-04; Z-score:-1.03E+00
Methylation in Case	7.27E-01 (Median)	Methylation in Control	7.89E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in colorectal cancer			[ 5 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.02E+00	Statistic Test	p-value:2.84E-02; Z-score:-3.09E-01
Methylation in Case	6.93E-01 (Median)	Methylation in Control	7.10E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in colorectal cancer			[ 5 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.06E+00	Statistic Test	p-value:3.01E-02; Z-score:-7.12E-01
Methylation in Case	7.54E-01 (Median)	Methylation in Control	8.03E-01 (Median)
Studied Phenotype	Colorectal cancer[ ICD-11:2B91]
Experimental Material	Patient tissue samples
Hepatocellular carcinoma	9 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS1500 (cg27520170)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.81E+00	Statistic Test	p-value:2.68E-13; Z-score:5.06E+00
Methylation in Case	3.62E-01 (Median)	Methylation in Control	2.00E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.08E+00	Statistic Test	p-value:4.88E-03; Z-score:9.23E-01
Methylation in Case	7.02E-01 (Median)	Methylation in Control	6.53E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS1500 (cg02707152)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.06E+00	Statistic Test	p-value:6.36E-03; Z-score:-4.46E-01
Methylation in Case	4.33E-01 (Median)	Methylation in Control	4.58E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS200 (cg21080921)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.10E+00	Statistic Test	p-value:2.06E-04; Z-score:9.17E-01
Methylation in Case	5.34E-01 (Median)	Methylation in Control	4.84E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.14E+00	Statistic Test	p-value:3.81E-03; Z-score:1.25E+00
Methylation in Case	6.39E-01 (Median)	Methylation in Control	5.63E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	TSS200 (cg14373018)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.13E+00	Statistic Test	p-value:5.90E-03; Z-score:1.25E+00
Methylation in Case	6.48E-01 (Median)	Methylation in Control	5.73E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.14E+00	Statistic Test	p-value:6.60E-08; Z-score:1.31E+00
Methylation in Case	6.27E-01 (Median)	Methylation in Control	5.48E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	Body (cg17156227)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.34E+00	Statistic Test	p-value:1.86E-12; Z-score:-5.91E+00
Methylation in Case	5.59E-01 (Median)	Methylation in Control	7.48E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC22A20 in hepatocellular carcinoma			[ 6 ]
Location	3'UTR (cg14321373)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-2.01E+00	Statistic Test	p-value:2.13E-22; Z-score:-7.20E+00
Methylation in Case	3.66E-01 (Median)	Methylation in Control	7.36E-01 (Median)
Studied Phenotype	Hepatocellular carcinoma[ ICD-11:2C12.02]
Experimental Material	Patient tissue samples
HIV infection	10 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	TSS1500 (cg02707152)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.40E+00	Statistic Test	p-value:2.33E-08; Z-score:1.78E+00
Methylation in Case	3.86E-01 (Median)	Methylation in Control	2.76E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.39E+00	Statistic Test	p-value:2.35E-03; Z-score:1.53E+00
Methylation in Case	3.43E-01 (Median)	Methylation in Control	2.47E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	TSS200 (cg21080921)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.37E+00	Statistic Test	p-value:2.65E-04; Z-score:1.62E+00
Methylation in Case	2.59E-01 (Median)	Methylation in Control	1.89E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	TSS200 (cg14373018)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.24E+00	Statistic Test	p-value:7.34E-04; Z-score:1.00E+00
Methylation in Case	2.88E-01 (Median)	Methylation in Control	2.33E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.11E+00	Statistic Test	p-value:9.30E-03; Z-score:4.38E-01
Methylation in Case	1.95E-01 (Median)	Methylation in Control	1.76E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	Body (cg02675946)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.54E+00	Statistic Test	p-value:2.54E-06; Z-score:2.64E+00
Methylation in Case	1.51E-01 (Median)	Methylation in Control	9.81E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	Body (cg23930334)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:3.24E+00	Statistic Test	p-value:7.86E-06; Z-score:2.68E+00
Methylation in Case	1.55E-01 (Median)	Methylation in Control	4.78E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	Body (cg08234507)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.08E+00	Statistic Test	p-value:7.99E-06; Z-score:-2.21E+00
Methylation in Case	8.01E-01 (Median)	Methylation in Control	8.68E-01 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon9	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:2.61E+00	Statistic Test	p-value:2.87E-05; Z-score:3.24E+00
Methylation in Case	1.16E-01 (Median)	Methylation in Control	4.46E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon10	Methylation of SLC22A20 in HIV infection			[ 7 ]
Location	Body (cg27428304)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.33E+00	Statistic Test	p-value:8.04E-04; Z-score:1.05E+00
Methylation in Case	8.23E-02 (Median)	Methylation in Control	6.19E-02 (Median)
Studied Phenotype	HIV infection[ ICD-11:1C62.Z]
Experimental Material	Patient tissue samples
Lung adenocarcinoma	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in lung adenocarcinoma			[ 8 ]
Location	TSS1500 (cg10133725)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.17E+00	Statistic Test	p-value:1.86E-02; Z-score:-1.90E+00
Methylation in Case	5.78E-01 (Median)	Methylation in Control	6.78E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in lung adenocarcinoma			[ 8 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.15E+00	Statistic Test	p-value:1.62E-03; Z-score:-4.05E+00
Methylation in Case	5.16E-01 (Median)	Methylation in Control	5.94E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in lung adenocarcinoma			[ 8 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.09E+00	Statistic Test	p-value:2.36E-02; Z-score:-1.74E+00
Methylation in Case	5.56E-01 (Median)	Methylation in Control	6.08E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in lung adenocarcinoma			[ 8 ]
Location	Body (cg08234507)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.08E+00	Statistic Test	p-value:3.24E-04; Z-score:-4.59E+00
Methylation in Case	8.06E-01 (Median)	Methylation in Control	8.69E-01 (Median)
Studied Phenotype	Lung adenocarcinoma[ ICD-11:2C25.0]
Experimental Material	Patient tissue samples
Papillary thyroid cancer	8 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	TSS1500 (cg02707152)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.08E+00	Statistic Test	p-value:4.62E-03; Z-score:4.99E-01
Methylation in Case	3.40E-01 (Median)	Methylation in Control	3.16E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	TSS200 (cg14373018)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.02E+00	Statistic Test	p-value:3.39E-02; Z-score:1.64E-01
Methylation in Case	6.13E-01 (Median)	Methylation in Control	6.02E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	TSS200 (cg02780017)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.06E+00	Statistic Test	p-value:4.02E-02; Z-score:6.74E-01
Methylation in Case	7.08E-01 (Median)	Methylation in Control	6.69E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	Body (cg23930334)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.33E+00	Statistic Test	p-value:5.65E-05; Z-score:8.95E-01
Methylation in Case	1.63E-01 (Median)	Methylation in Control	1.23E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon5	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	Body (cg02675946)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.12E+00	Statistic Test	p-value:1.45E-04; Z-score:5.84E-01
Methylation in Case	9.17E-02 (Median)	Methylation in Control	8.21E-02 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon6	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	Body (cg27428304)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.18E+00	Statistic Test	p-value:2.32E-04; Z-score:7.39E-01
Methylation in Case	8.31E-02 (Median)	Methylation in Control	7.04E-02 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon7	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	Body (cg08234507)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.01E+00	Statistic Test	p-value:4.29E-03; Z-score:-5.75E-01
Methylation in Case	9.20E-01 (Median)	Methylation in Control	9.30E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon8	Methylation of SLC22A20 in papillary thyroid cancer			[ 9 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.10E+00	Statistic Test	p-value:1.54E-02; Z-score:2.76E-01
Methylation in Case	1.43E-01 (Median)	Methylation in Control	1.30E-01 (Median)
Studied Phenotype	Papillary thyroid cancer[ ICD-11:2D10.1]
Experimental Material	Patient tissue samples
Atypical teratoid rhabdoid tumor	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in atypical teratoid rhabdoid tumor			[ 10 ]
Location	1stExon (cg25010124)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.65E+00	Statistic Test	p-value:4.27E-16; Z-score:-2.64E+00
Methylation in Case	4.74E-01 (Median)	Methylation in Control	7.84E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in atypical teratoid rhabdoid tumor			[ 10 ]
Location	Body (cg02675946)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.29E+00	Statistic Test	p-value:2.03E-04; Z-score:1.12E+00
Methylation in Case	7.76E-01 (Median)	Methylation in Control	6.02E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in atypical teratoid rhabdoid tumor			[ 10 ]
Location	Body (cg08234507)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.07E+00	Statistic Test	p-value:5.62E-03; Z-score:-6.29E-01
Methylation in Case	7.90E-01 (Median)	Methylation in Control	8.48E-01 (Median)
Studied Phenotype	Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]
Experimental Material	Patient tissue samples
Renal cell carcinoma	4 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in clear cell renal cell carcinoma			[ 11 ]
Location	Body (cg02675946)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.30E+00	Statistic Test	p-value:1.16E-02; Z-score:1.34E+00
Methylation in Case	5.66E-02 (Median)	Methylation in Control	4.35E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in clear cell renal cell carcinoma			[ 11 ]
Location	Body (cg23930334)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.41E+00	Statistic Test	p-value:1.80E-02; Z-score:1.10E+00
Methylation in Case	3.91E-02 (Median)	Methylation in Control	2.78E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in clear cell renal cell carcinoma			[ 11 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.39E+00	Statistic Test	p-value:2.04E-02; Z-score:1.90E+00
Methylation in Case	2.96E-02 (Median)	Methylation in Control	2.13E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon4	Methylation of SLC22A20 in clear cell renal cell carcinoma			[ 11 ]
Location	Body (cg27428304)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.28E+00	Statistic Test	p-value:3.84E-02; Z-score:9.03E-01
Methylation in Case	2.77E-02 (Median)	Methylation in Control	2.17E-02 (Median)
Studied Phenotype	Renal cell carcinoma[ ICD-11:2C90]
Experimental Material	Patient tissue samples
Colon cancer	3 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in colon adenocarcinoma			[ 12 ]
Location	Body (cg22179256)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.05E+00	Statistic Test	p-value:1.75E-03; Z-score:-2.94E+00
Methylation in Case	7.51E-01 (Median)	Methylation in Control	7.91E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon2	Methylation of SLC22A20 in colon adenocarcinoma			[ 12 ]
Location	Body (cg20544437)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.06E+00	Statistic Test	p-value:2.99E-03; Z-score:1.12E+00
Methylation in Case	8.52E-01 (Median)	Methylation in Control	8.02E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Epigenetic Phenomenon3	Methylation of SLC22A20 in colon adenocarcinoma			[ 12 ]
Location	3'UTR (cg14321373)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-1.09E+00	Statistic Test	p-value:2.58E-03; Z-score:-4.28E+00
Methylation in Case	8.16E-01 (Median)	Methylation in Control	8.91E-01 (Median)
Studied Phenotype	Colon cancer[ ICD-11:2B90]
Experimental Material	Patient tissue samples
Panic disorder	1 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in panic disorder			[ 13 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:-9.56E-01	Statistic Test	p-value:5.07E-04; Z-score:-4.28E-01
Methylation in Case	-5.66E+00 (Median)	Methylation in Control	-5.41E+00 (Median)
Studied Phenotype	Panic disorder[ ICD-11:6B01]
Experimental Material	Patient tissue samples
Systemic lupus erythematosus	1 Epigenetic Phenomena Related to This Phenotype		Click to Show/Hide the Full List
Epigenetic Phenomenon1	Methylation of SLC22A20 in systemic lupus erythematosus			[ 14 ]
Location	Body (cg19323951)
Epigenetic Type	Methylation	Experiment Method	Infinium HumanMethylation450 BeadChip
Methylation Fold Change	Fold Change:1.06E+00	Statistic Test	p-value:2.72E-02; Z-score:7.59E-02
Methylation in Case	3.87E-02 (Median)	Methylation in Control	3.66E-02 (Median)
Studied Phenotype	Systemic lupus erythematosus[ ICD-11:4A40.0]
Experimental Material	Patient tissue samples

References
1	Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
2	Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
3	DNA Methylation Dynamics in Urological Tumors.
4	Genome-wide Scan for Methylation Profiles in Breast Cancer
5	Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
6	Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
7	HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
8	DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
9	Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
10	Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
11	A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
12	Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
13	DNA Methylation signatures in panic disorder. Transl Psychiatry. 2017 Dec 18;7(12):1287.
14	Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9(8):e1003678.

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