General Information of Drug Transporter (DT)
DT ID DTD0128 Transporter Info
Gene Name SLC19A3
Transporter Name Thiamine transporter 2
Gene ID
80704
UniProt ID
Q9BZV2
Epigenetic Regulations of This DT (EGR)

Methylation

  Gastric cancer

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Hypermethylation of SLC19A3 in gastric cancer [ 1 ]

Location

Promoter

Epigenetic Type

Methylation Experiment Method Bisulfite sequencing

Related Molecular Changes

Down regulation ofSLC19A3 Experiment Method RT-qPCR

Studied Phenotype

Gastric cancer[ ICD-11:2B72]

Frequency

52 (51%) out of the 101 studied tumor samples

Experimental Material

Multiple cell lines of human

Additional Notes

Hypermethylation within the SLC19A3 promoter is responsible for the down-regulation of SLC19A3 in gastric cancer.

  Breast cancer

         13 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Hypermethylation of SLC19A3 in breast cancer [ 2 ]

Location

Promoter

Epigenetic Type

Methylation Experiment Method Methylation-specific PCR

Related Molecular Changes

Down regulation ofSLC19A3 Experiment Method RT-qPCR

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

Additional Notes

SLC19A3 promoter Hypermethylation in plasma may be a novel biomarker for breast and gastric cancer diagnosis.

  Epigenetic Phenomenon2

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.83E+00 Statistic Test p-value:1.41E-17; Z-score:3.38E+00

Methylation in Case

3.65E-01 (Median) Methylation in Control 1.99E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.31E+00 Statistic Test p-value:3.06E-13; Z-score:3.12E+00

Methylation in Case

2.24E-01 (Median) Methylation in Control 9.70E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.52E+00 Statistic Test p-value:1.33E-07; Z-score:1.91E+00

Methylation in Case

9.47E-02 (Median) Methylation in Control 6.21E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.45E+00 Statistic Test p-value:1.57E-07; Z-score:1.69E+00

Methylation in Case

1.23E-01 (Median) Methylation in Control 8.46E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

TSS200 (cg02562740)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.51E+00 Statistic Test p-value:6.64E-04; Z-score:9.88E-01

Methylation in Case

2.37E-02 (Median) Methylation in Control 1.57E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

TSS200 (cg20440901)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.86E+00 Statistic Test p-value:4.18E-03; Z-score:7.50E-01

Methylation in Case

2.96E-02 (Median) Methylation in Control 1.59E-02 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

TSS200 (cg05844583)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.21E+00 Statistic Test p-value:2.89E-02; Z-score:1.21E-01

Methylation in Case

6.61E-03 (Median) Methylation in Control 5.45E-03 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

Body (cg11543686)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:8.55E-07; Z-score:-9.97E-01

Methylation in Case

8.47E-01 (Median) Methylation in Control 8.77E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

Body (cg19863633)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:7.72E-06; Z-score:-1.27E+00

Methylation in Case

8.59E-01 (Median) Methylation in Control 8.91E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

Body (cg04529897)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:2.95E-05; Z-score:-1.14E+00

Methylation in Case

8.50E-01 (Median) Methylation in Control 8.90E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

Body (cg21194765)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.09E-02; Z-score:-6.86E-01

Methylation in Case

8.27E-01 (Median) Methylation in Control 8.60E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SLC19A3 in breast cancer [ 5 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.11E+00 Statistic Test p-value:3.81E-05; Z-score:-1.11E+00

Methylation in Case

7.22E-01 (Median) Methylation in Control 8.02E-01 (Median)

Studied Phenotype

Breast cancer[ ICD-11:2C60-2C6Z]

Experimental Material

Patient tissue samples

  Atypical teratoid rhabdoid tumor

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

5'UTR (cg03894284)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.44E+00 Statistic Test p-value:2.15E-08; Z-score:-1.18E+00

Methylation in Case

3.75E-01 (Median) Methylation in Control 5.40E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.09E+00 Statistic Test p-value:1.16E-07; Z-score:-1.32E+00

Methylation in Case

8.28E-01 (Median) Methylation in Control 9.06E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.16E+00 Statistic Test p-value:6.50E-07; Z-score:9.90E-01

Methylation in Case

8.20E-01 (Median) Methylation in Control 7.10E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:1.07E-05; Z-score:-1.22E+00

Methylation in Case

8.59E-01 (Median) Methylation in Control 8.96E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

Body (cg04529897)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-2.07E+00 Statistic Test p-value:8.56E-04; Z-score:-1.27E+00

Methylation in Case

2.37E-01 (Median) Methylation in Control 4.90E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

Body (cg11543686)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.08E+00 Statistic Test p-value:2.29E-02; Z-score:4.44E-01

Methylation in Case

9.08E-01 (Median) Methylation in Control 8.38E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in atypical teratoid rhabdoid tumor [ 3 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.06E+00 Statistic Test p-value:2.40E-14; Z-score:2.26E+00

Methylation in Case

6.06E-01 (Median) Methylation in Control 2.94E-01 (Median)

Studied Phenotype

Atypical teratoid rhabdoid tumor[ ICD-11:2A00.1Y]

Experimental Material

Patient tissue samples

  Bladder cancer

         15 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

5'UTR (cg03894284)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.22E+00 Statistic Test p-value:1.79E-04; Z-score:-2.74E+00

Methylation in Case

5.99E-01 (Median) Methylation in Control 7.30E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.94E+00 Statistic Test p-value:3.30E-04; Z-score:1.61E+01

Methylation in Case

3.22E-01 (Median) Methylation in Control 1.10E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.10E+00 Statistic Test p-value:6.97E-04; Z-score:1.64E+01

Methylation in Case

4.59E-01 (Median) Methylation in Control 2.19E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.15E+00 Statistic Test p-value:2.77E-02; Z-score:2.71E+00

Methylation in Case

7.82E-01 (Median) Methylation in Control 6.82E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS1500 (cg09726804)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.04E+00 Statistic Test p-value:4.10E-02; Z-score:-1.25E+00

Methylation in Case

7.69E-01 (Median) Methylation in Control 7.97E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.76E+00 Statistic Test p-value:4.35E-03; Z-score:7.61E+00

Methylation in Case

9.53E-02 (Median) Methylation in Control 5.41E-02 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.26E+00 Statistic Test p-value:1.03E-02; Z-score:3.00E+00

Methylation in Case

1.03E-01 (Median) Methylation in Control 8.22E-02 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS200 (cg20440901)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.85E+00 Statistic Test p-value:1.11E-02; Z-score:1.32E+00

Methylation in Case

2.38E-02 (Median) Methylation in Control 1.29E-02 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS200 (cg02562740)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.50E+00 Statistic Test p-value:2.10E-02; Z-score:1.90E+00

Methylation in Case

2.35E-02 (Median) Methylation in Control 1.57E-02 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

TSS200 (cg05844583)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.59E+00 Statistic Test p-value:4.53E-02; Z-score:1.68E+00

Methylation in Case

6.15E-03 (Median) Methylation in Control 2.37E-03 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

Body (cg11543686)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.10E+00 Statistic Test p-value:1.19E-04; Z-score:-9.66E+00

Methylation in Case

8.08E-01 (Median) Methylation in Control 8.92E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

Body (cg21194765)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:2.86E-03; Z-score:-4.95E+00

Methylation in Case

8.65E-01 (Median) Methylation in Control 9.08E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon13

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

Body (cg19863633)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.02E+00 Statistic Test p-value:3.80E-03; Z-score:-2.47E+00

Methylation in Case

8.80E-01 (Median) Methylation in Control 8.99E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon14

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

Body (cg04529897)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:4.35E-03; Z-score:-1.19E+00

Methylation in Case

8.88E-01 (Median) Methylation in Control 9.00E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon15

Methylation of SLC19A3 in bladder cancer [ 4 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.20E+00 Statistic Test p-value:1.42E-04; Z-score:-6.85E+00

Methylation in Case

6.79E-01 (Median) Methylation in Control 8.14E-01 (Median)

Studied Phenotype

Bladder cancer[ ICD-11:2C94]

Experimental Material

Patient tissue samples

  Renal cell carcinoma

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.65E+00 Statistic Test p-value:1.16E-04; Z-score:1.22E+00

Methylation in Case

2.03E-01 (Median) Methylation in Control 1.23E-01 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.08E+00 Statistic Test p-value:3.47E-04; Z-score:1.19E+00

Methylation in Case

7.53E-02 (Median) Methylation in Control 3.62E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

TSS200 (cg02562740)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.17E+00 Statistic Test p-value:2.16E-07; Z-score:1.51E+00

Methylation in Case

2.38E-02 (Median) Methylation in Control 2.02E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

TSS200 (cg20440901)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.12E+00 Statistic Test p-value:5.92E-06; Z-score:1.08E+00

Methylation in Case

2.89E-02 (Median) Methylation in Control 2.57E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

TSS200 (cg05844583)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.14E+00 Statistic Test p-value:1.23E-05; Z-score:1.21E+00

Methylation in Case

2.53E-02 (Median) Methylation in Control 2.23E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.35E+00 Statistic Test p-value:1.15E-03; Z-score:8.58E-01

Methylation in Case

4.99E-02 (Median) Methylation in Control 3.70E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in clear cell renal cell carcinoma [ 6 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.18E+00 Statistic Test p-value:1.73E-03; Z-score:3.37E-01

Methylation in Case

2.51E-02 (Median) Methylation in Control 2.14E-02 (Median)

Studied Phenotype

Renal cell carcinoma[ ICD-11:2C90]

Experimental Material

Patient tissue samples

  Colon cancer

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

5'UTR (cg01330016)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.25E+00 Statistic Test p-value:8.38E-05; Z-score:-4.62E+00

Methylation in Case

6.26E-01 (Median) Methylation in Control 7.85E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

TSS1500 (cg01532168)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.32E+00 Statistic Test p-value:6.12E-07; Z-score:1.73E+00

Methylation in Case

5.64E-01 (Median) Methylation in Control 4.26E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

TSS200 (cg10150176)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.16E+00 Statistic Test p-value:2.15E-04; Z-score:-5.00E+00

Methylation in Case

7.10E-01 (Median) Methylation in Control 8.25E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

TSS200 (cg04309194)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.16E+00 Statistic Test p-value:3.07E-04; Z-score:-2.60E+00

Methylation in Case

5.22E-01 (Median) Methylation in Control 6.08E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

Body (cg16163535)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.21E+00 Statistic Test p-value:4.43E-06; Z-score:-3.68E+00

Methylation in Case

6.96E-01 (Median) Methylation in Control 8.45E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

Body (cg24642933)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.34E+00 Statistic Test p-value:8.55E-06; Z-score:-2.87E+00

Methylation in Case

4.46E-01 (Median) Methylation in Control 5.98E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in colon adenocarcinoma [ 7 ]

Location

Body (cg08830588)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.16E+00 Statistic Test p-value:3.47E-05; Z-score:-1.14E+00

Methylation in Case

4.21E-01 (Median) Methylation in Control 4.87E-01 (Median)

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Patient tissue samples

  Colorectal cancer

           7 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:3.42E-05; Z-score:1.19E+00

Methylation in Case

9.13E-01 (Median) Methylation in Control 8.27E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

5'UTR (cg03894284)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.29E+00 Statistic Test p-value:4.47E-05; Z-score:1.38E+00

Methylation in Case

8.19E-01 (Median) Methylation in Control 6.35E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:1.70E-02; Z-score:3.85E-01

Methylation in Case

3.42E-01 (Median) Methylation in Control 3.11E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.04E+00 Statistic Test p-value:2.08E-02; Z-score:1.26E-01

Methylation in Case

1.78E-01 (Median) Methylation in Control 1.70E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

TSS1500 (cg09726804)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:1.34E-02; Z-score:7.24E-01

Methylation in Case

8.98E-01 (Median) Methylation in Control 8.76E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in colorectal cancer [ 8 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.05E+00 Statistic Test p-value:1.07E-02; Z-score:1.47E+00

Methylation in Case

8.59E-01 (Median) Methylation in Control 8.20E-01 (Median)

Studied Phenotype

Colorectal cancer[ ICD-11:2B91]

Experimental Material

Patient tissue samples

  Hepatocellular carcinoma

         11 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

5'UTR (cg03894284)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.38E+00 Statistic Test p-value:1.80E-06; Z-score:-1.20E+00

Methylation in Case

3.59E-01 (Median) Methylation in Control 4.95E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.42E+00 Statistic Test p-value:1.94E-06; Z-score:-1.03E+00

Methylation in Case

9.17E-02 (Median) Methylation in Control 1.31E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.32E+00 Statistic Test p-value:2.25E-06; Z-score:-1.04E+00

Methylation in Case

1.82E-01 (Median) Methylation in Control 2.41E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

TSS1500 (cg04981611)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:5.23E+00 Statistic Test p-value:3.54E-16; Z-score:1.50E+01

Methylation in Case

3.46E-01 (Median) Methylation in Control 6.61E-02 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.35E+00 Statistic Test p-value:1.25E-06; Z-score:-1.16E+00

Methylation in Case

7.82E-02 (Median) Methylation in Control 1.06E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.31E+00 Statistic Test p-value:3.41E-06; Z-score:-8.16E-01

Methylation in Case

6.86E-02 (Median) Methylation in Control 8.95E-02 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

Body (cg12303470)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.76E+00 Statistic Test p-value:2.68E-24; Z-score:-1.74E+01

Methylation in Case

4.66E-01 (Median) Methylation in Control 8.20E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

Body (cg18869815)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.62E+00 Statistic Test p-value:1.58E-17; Z-score:-4.17E+00

Methylation in Case

4.52E-01 (Median) Methylation in Control 7.33E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

Body (cg05118455)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.53E+00 Statistic Test p-value:5.12E-16; Z-score:-1.20E+01

Methylation in Case

5.35E-01 (Median) Methylation in Control 8.17E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

Body (cg19863633)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.16E-02; Z-score:-5.83E-01

Methylation in Case

8.78E-01 (Median) Methylation in Control 8.89E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SLC19A3 in hepatocellular carcinoma [ 9 ]

Location

Body (cg21194765)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:3.97E-02; Z-score:-6.88E-02

Methylation in Case

8.80E-01 (Median) Methylation in Control 8.81E-01 (Median)

Studied Phenotype

Hepatocellular carcinoma[ ICD-11:2C12.02]

Experimental Material

Patient tissue samples

  HIV infection

           8 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.28E+00 Statistic Test p-value:3.04E-06; Z-score:1.56E+00

Methylation in Case

2.63E-01 (Median) Methylation in Control 2.05E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.02E+00 Statistic Test p-value:1.11E-03; Z-score:9.42E-01

Methylation in Case

9.06E-01 (Median) Methylation in Control 8.87E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:2.91E-02; Z-score:2.99E-01

Methylation in Case

4.75E-01 (Median) Methylation in Control 4.60E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.37E+00 Statistic Test p-value:3.94E-05; Z-score:1.53E+00

Methylation in Case

1.60E-01 (Median) Methylation in Control 1.17E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.40E+00 Statistic Test p-value:1.02E-04; Z-score:1.57E+00

Methylation in Case

1.46E-01 (Median) Methylation in Control 1.04E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

TSS200 (cg02562740)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.49E+00 Statistic Test p-value:2.27E-03; Z-score:1.07E+00

Methylation in Case

3.66E-02 (Median) Methylation in Control 2.45E-02 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

TSS200 (cg20440901)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.31E+00 Statistic Test p-value:2.77E-02; Z-score:7.38E-01

Methylation in Case

4.34E-02 (Median) Methylation in Control 3.32E-02 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC19A3 in HIV infection [ 10 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.05E+00 Statistic Test p-value:5.76E-03; Z-score:-8.46E-01

Methylation in Case

8.23E-01 (Median) Methylation in Control 8.62E-01 (Median)

Studied Phenotype

HIV infection[ ICD-11:1C62.Z]

Experimental Material

Patient tissue samples

  Lung adenocarcinoma

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

5'UTR (cg03894284)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.20E+00 Statistic Test p-value:1.40E-04; Z-score:2.36E+00

Methylation in Case

8.39E-01 (Median) Methylation in Control 7.02E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

5'UTR (cg25713185)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.62E+00 Statistic Test p-value:6.22E-04; Z-score:3.35E+00

Methylation in Case

2.88E-01 (Median) Methylation in Control 1.77E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

5'UTR (cg07417745)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.50E+00 Statistic Test p-value:1.28E-03; Z-score:3.40E+00

Methylation in Case

4.23E-01 (Median) Methylation in Control 2.81E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.08E+00 Statistic Test p-value:7.73E-03; Z-score:1.83E+00

Methylation in Case

8.41E-01 (Median) Methylation in Control 7.79E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.53E+00 Statistic Test p-value:5.21E-03; Z-score:3.09E+00

Methylation in Case

1.59E-01 (Median) Methylation in Control 1.03E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in lung adenocarcinoma [ 11 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.45E+00 Statistic Test p-value:7.40E-03; Z-score:4.20E+00

Methylation in Case

1.71E-01 (Median) Methylation in Control 1.18E-01 (Median)

Studied Phenotype

Lung adenocarcinoma[ ICD-11:2C25.0]

Experimental Material

Patient tissue samples

  Pancretic ductal adenocarcinoma

         12 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

5'UTR (cg20632143)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.18E+00 Statistic Test p-value:4.47E-08; Z-score:9.47E-01

Methylation in Case

4.55E-01 (Median) Methylation in Control 3.85E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

TSS1500 (cg07845390)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.96E+00 Statistic Test p-value:1.76E-23; Z-score:4.95E+00

Methylation in Case

2.43E-01 (Median) Methylation in Control 8.22E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

TSS1500 (cg22935149)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.31E+00 Statistic Test p-value:4.98E-14; Z-score:8.68E-01

Methylation in Case

6.65E-02 (Median) Methylation in Control 5.09E-02 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

1stExon (cg26923490)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:2.35E+00 Statistic Test p-value:8.88E-23; Z-score:3.94E+00

Methylation in Case

4.72E-01 (Median) Methylation in Control 2.01E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

1stExon (cg01135800)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.06E+00 Statistic Test p-value:4.05E-02; Z-score:-5.56E-01

Methylation in Case

7.87E-01 (Median) Methylation in Control 8.32E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg09565111)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.10E+00 Statistic Test p-value:8.80E-10; Z-score:-1.44E+00

Methylation in Case

6.73E-01 (Median) Methylation in Control 7.42E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon7

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg26504422)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.17E+00 Statistic Test p-value:9.10E-08; Z-score:1.92E+00

Methylation in Case

8.24E-01 (Median) Methylation in Control 7.07E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon8

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg09606015)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.28E+00 Statistic Test p-value:3.00E-05; Z-score:-9.61E-01

Methylation in Case

1.37E-01 (Median) Methylation in Control 1.75E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon9

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg13971265)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:7.56E-04; Z-score:1.21E+00

Methylation in Case

7.79E-01 (Median) Methylation in Control 7.07E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon10

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg21627218)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.01E+00 Statistic Test p-value:2.40E-03; Z-score:7.83E-01

Methylation in Case

9.25E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon11

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg23761815)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.16E-02; Z-score:-3.74E-01

Methylation in Case

8.81E-01 (Median) Methylation in Control 8.88E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon12

Methylation of SLC19A3 in pancretic ductal adenocarcinoma [ 12 ]

Location

Body (cg18196463)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:3.09E-02; Z-score:-4.14E-01

Methylation in Case

9.30E-01 (Median) Methylation in Control 9.35E-01 (Median)

Studied Phenotype

Pancretic ductal adenocarcinoma[ ICD-11:2C10.0]

Experimental Material

Patient tissue samples

  Papillary thyroid cancer

           6 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

5'UTR (cg13774987)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.10E+00 Statistic Test p-value:2.55E-03; Z-score:1.07E+00

Methylation in Case

8.36E-01 (Median) Methylation in Control 7.58E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

TSS200 (cg19850080)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.11E+00 Statistic Test p-value:3.83E-03; Z-score:5.24E-01

Methylation in Case

7.54E-02 (Median) Methylation in Control 6.80E-02 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

TSS200 (cg01142776)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.09E+00 Statistic Test p-value:2.02E-02; Z-score:3.51E-01

Methylation in Case

7.75E-02 (Median) Methylation in Control 7.15E-02 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon4

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

TSS200 (cg05844583)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.07E+00 Statistic Test p-value:2.18E-02; Z-score:6.20E-01

Methylation in Case

5.31E-02 (Median) Methylation in Control 4.97E-02 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon5

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

Body (cg11543686)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:1.20E-03; Z-score:-5.21E-01

Methylation in Case

8.91E-01 (Median) Methylation in Control 9.02E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon6

Methylation of SLC19A3 in papillary thyroid cancer [ 13 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.01E+00 Statistic Test p-value:4.29E-03; Z-score:-1.84E-01

Methylation in Case

8.59E-01 (Median) Methylation in Control 8.64E-01 (Median)

Studied Phenotype

Papillary thyroid cancer[ ICD-11:2D10.1]

Experimental Material

Patient tissue samples

  Prostate cancer

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in prostate cancer [ 14 ]

Location

TSS200 (cg02772823)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.97E+00 Statistic Test p-value:1.24E-02; Z-score:-2.78E+00

Methylation in Case

2.86E-01 (Median) Methylation in Control 5.64E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in prostate cancer [ 14 ]

Location

Body (cg07986907)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.15E+00 Statistic Test p-value:5.84E-03; Z-score:2.70E+00

Methylation in Case

9.38E-01 (Median) Methylation in Control 8.16E-01 (Median)

Studied Phenotype

Prostate cancer[ ICD-11:2C82]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Moderate hypermethylation of SLC19A3 in prostate cancer than that in healthy individual

Studied Phenotype

Prostate cancer [ICD-11:2C82]

The Methylation Level of Disease Section Compare with the Healthy Individual

p-value:1.22E-34; Fold-change:0.233589324; Z-score:11.29860515
DT methylation level in the diseased tissue of patients
DT methylation level in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Methylation Barchart for All Samples

  Systemic lupus erythematosus

           3 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in systemic lupus erythematosus [ 15 ]

Location

TSS200 (cg02562740)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.03E+00 Statistic Test p-value:1.71E-02; Z-score:1.00E-01

Methylation in Case

3.45E-02 (Median) Methylation in Control 3.35E-02 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon2

Methylation of SLC19A3 in systemic lupus erythematosus [ 15 ]

Location

Body (cg21194765)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:6.12E-03; Z-score:-1.02E-01

Methylation in Case

9.15E-01 (Median) Methylation in Control 9.17E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Epigenetic Phenomenon3

Methylation of SLC19A3 in systemic lupus erythematosus [ 15 ]

Location

Body (cg04529897)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:-1.00E+00 Statistic Test p-value:3.70E-02; Z-score:-9.31E-02

Methylation in Case

9.20E-01 (Median) Methylation in Control 9.22E-01 (Median)

Studied Phenotype

Systemic lupus erythematosus[ ICD-11:4A40.0]

Experimental Material

Patient tissue samples

  Depression

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Methylation of SLC19A3 in depression [ 16 ]

Location

3'UTR (cg04091914)

Epigenetic Type

Methylation Experiment Method Infinium HumanMethylation450 BeadChip

Methylation Fold Change

Fold Change:1.02E+00 Statistic Test p-value:2.28E-02; Z-score:6.59E-01

Methylation in Case

7.71E-01 (Median) Methylation in Control 7.53E-01 (Median)

Studied Phenotype

Depression[ ICD-11:6A8Z]

Experimental Material

Patient tissue samples

  Lymphoma

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Significant hypermethylation of SLC19A3 in lymphoma than that in healthy individual

Studied Phenotype

Lymphoma [ICD-11:2B30]

The Methylation Level of Disease Section Compare with the Healthy Individual

p-value:1.63E-28; Fold-change:0.618985571; Z-score:29.85128227
DT methylation level in the diseased tissue of patients
DT methylation level in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Methylation Barchart for All Samples

  Prostate cancer metastasis

           1 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Significant hypermethylation of SLC19A3 in prostate cancer metastasis than that in healthy individual

Studied Phenotype

Prostate cancer metastasis [ICD-11:2.00E+06]

The Methylation Level of Disease Section Compare with the Healthy Individual

p-value:1.96E-06; Fold-change:0.574690231; Z-score:26.50513269
DT methylation level in the diseased tissue of patients
DT methylation level in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Methylation Barchart for All Samples

Histone acetylation

  Colon cancer

           2 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

Hypoacetylation of SLC19A3 in colon cancer (compare with trichostatin A-treatment counterpart cells) [ 17 ]

Location

Promoter

Epigenetic Type

Histone acetylation Experiment Method Chromatin immunoprecipitation

Related Molecular Changes

Down regulation ofSLC19A3 Experiment Method RT-qPCR

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Multiple cell lines of human

Additional Notes

TSA treatment increased histone H3 acetylation of SLC19A3 promoter region in all 4 colon cancer cell lines examined.

  Epigenetic Phenomenon2

Hypoacetylation of SLC19A3 in colon cancer (compare with TSA-treatment counterpart cells) [ 17 ]

Location

Promoter

Epigenetic Type

Histone acetylation Experiment Method Chromatin immunoprecipitation

Related Molecular Changes

Down regulation ofSLC19A3 Experiment Method RT-qPCR

Studied Phenotype

Colon cancer[ ICD-11:2B90]

Experimental Material

Multiple cell lines of human

Additional Notes

In the 4 colon cancer cells examined, SLC19A3 mRNA expression is down-regulated by histone deacetylation.

microRNA

  Unclear Phenotype

         83 Epigenetic Phenomena Related to This Phenotype Click to Show/Hide the Full List

  Epigenetic Phenomenon1

let-7a directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7a miRNA Mature ID let-7a-5p

miRNA Sequence

UGAGGUAGUAGGUUGUAUAGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon2

let-7b directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7b miRNA Mature ID let-7b-5p

miRNA Sequence

UGAGGUAGUAGGUUGUGUGGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon3

let-7c directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7c miRNA Mature ID let-7c-5p

miRNA Sequence

UGAGGUAGUAGGUUGUAUGGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon4

let-7d directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7d miRNA Mature ID let-7d-5p

miRNA Sequence

AGAGGUAGUAGGUUGCAUAGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon5

let-7e directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7e miRNA Mature ID let-7e-5p

miRNA Sequence

UGAGGUAGGAGGUUGUAUAGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon6

let-7f directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7f miRNA Mature ID let-7f-5p

miRNA Sequence

UGAGGUAGUAGAUUGUAUAGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon7

let-7g directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7g miRNA Mature ID let-7g-5p

miRNA Sequence

UGAGGUAGUAGUUUGUACAGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon8

let-7i directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

let-7i miRNA Mature ID let-7i-5p

miRNA Sequence

UGAGGUAGUAGUUUGUGCUGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon9

miR-1273h directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-1273h miRNA Mature ID miR-1273h-5p

miRNA Sequence

CUGGGAGGUCAAGGCUGCAGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon10

miR-1296 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-1296 miRNA Mature ID miR-1296-3p

miRNA Sequence

GAGUGGGGCUUCGACCCUAACC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon11

miR-1343 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-1343 miRNA Mature ID miR-1343-5p

miRNA Sequence

UGGGGAGCGGCCCCCGGGUGGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon12

miR-135a directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-135a miRNA Mature ID miR-135a-5p

miRNA Sequence

UAUGGCUUUUUAUUCCUAUGUGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon13

miR-135b directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-135b miRNA Mature ID miR-135b-5p

miRNA Sequence

UAUGGCUUUUCAUUCCUAUGUGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon14

miR-149 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-149 miRNA Mature ID miR-149-3p

miRNA Sequence

AGGGAGGGACGGGGGCUGUGC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon15

miR-187 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-187 miRNA Mature ID miR-187-5p

miRNA Sequence

GGCUACAACACAGGACCCGGGC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon16

miR-202 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-202 miRNA Mature ID miR-202-3p

miRNA Sequence

AGAGGUAUAGGGCAUGGGAA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon17

miR-203b directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-203b miRNA Mature ID miR-203b-3p

miRNA Sequence

UUGAACUGUUAAGAACCACUGGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon18

miR-216a directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-216a miRNA Mature ID miR-216a-5p

miRNA Sequence

UAAUCUCAGCUGGCAACUGUGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon19

miR-216b directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-216b miRNA Mature ID miR-216b-5p

miRNA Sequence

AAAUCUCUGCAGGCAAAUGUGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon20

miR-221 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-221 miRNA Mature ID miR-221-3p

miRNA Sequence

AGCUACAUUGUCUGCUGGGUUUC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon21

miR-222 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-222 miRNA Mature ID miR-222-3p

miRNA Sequence

AGCUACAUCUGGCUACUGGGU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon22

miR-24 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-24 miRNA Mature ID miR-24-3p

miRNA Sequence

UGGCUCAGUUCAGCAGGAACAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon23

miR-30b directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-30b miRNA Mature ID miR-30b-3p

miRNA Sequence

CUGGGAGGUGGAUGUUUACUUC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon24

miR-30c-1 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-30c-1 miRNA Mature ID miR-30c-1-3p

miRNA Sequence

CUGGGAGAGGGUUGUUUACUCC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon25

miR-30c-2 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-30c-2 miRNA Mature ID miR-30c-2-3p

miRNA Sequence

CUGGGAGAAGGCUGUUUACUCU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon26

miR-3122 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3122 miRNA Mature ID miR-3122

miRNA Sequence

GUUGGGACAAGAGGACGGUCUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon27

miR-3124 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3124 miRNA Mature ID miR-3124-3p

miRNA Sequence

ACUUUCCUCACUCCCGUGAAGU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon28

miR-3150a directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-3150a miRNA Mature ID miR-3150a-3p

miRNA Sequence

CUGGGGAGAUCCUCGAGGUUGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon29

miR-3175 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-3175 miRNA Mature ID miR-3175

miRNA Sequence

CGGGGAGAGAACGCAGUGACGU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon30

miR-330 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-330 miRNA Mature ID miR-330-3p

miRNA Sequence

GCAAAGCACACGGCCUGCAGAGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon31

miR-3689a directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3689a miRNA Mature ID miR-3689a-3p

miRNA Sequence

CUGGGAGGUGUGAUAUCGUGGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon32

miR-3689b directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3689b miRNA Mature ID miR-3689b-3p

miRNA Sequence

CUGGGAGGUGUGAUAUUGUGGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon33

miR-3689c directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3689c miRNA Mature ID miR-3689c

miRNA Sequence

CUGGGAGGUGUGAUAUUGUGGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon34

miR-3689d directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-3689d miRNA Mature ID miR-3689d

miRNA Sequence

GGGAGGUGUGAUCUCACACUCG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon35

miR-371a directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-371a miRNA Mature ID miR-371a-5p

miRNA Sequence

ACUCAAACUGUGGGGGCACU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon36

miR-371b directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-371b miRNA Mature ID miR-371b-5p

miRNA Sequence

ACUCAAAAGAUGGCGGCACUUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon37

miR-372 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-372 miRNA Mature ID miR-372-5p

miRNA Sequence

CCUCAAAUGUGGAGCACUAUUCU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon38

miR-373 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-373 miRNA Mature ID miR-373-5p

miRNA Sequence

ACUCAAAAUGGGGGCGCUUUCC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon39

miR-3913 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3913 miRNA Mature ID miR-3913-5p

miRNA Sequence

UUUGGGACUGAUCUUGAUGUCU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon40

miR-3929 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-3929 miRNA Mature ID miR-3929

miRNA Sequence

GAGGCUGAUGUGAGUAGACCACU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon41

miR-4284 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4284 miRNA Mature ID miR-4284

miRNA Sequence

GGGCUCACAUCACCCCAU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon42

miR-4311 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4311 miRNA Mature ID miR-4311

miRNA Sequence

GAAAGAGAGCUGAGUGUG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon43

miR-4458 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4458 miRNA Mature ID miR-4458

miRNA Sequence

AGAGGUAGGUGUGGAAGAA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon44

miR-4478 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4478 miRNA Mature ID miR-4478

miRNA Sequence

GAGGCUGAGCUGAGGAG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon45

miR-4481 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4481 miRNA Mature ID miR-4481

miRNA Sequence

GGAGUGGGCUGGUGGUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon46

miR-4500 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4500 miRNA Mature ID miR-4500

miRNA Sequence

UGAGGUAGUAGUUUCUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon47

miR-4680 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4680 miRNA Mature ID miR-4680-5p

miRNA Sequence

AGAACUCUUGCAGUCUUAGAUGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon48

miR-4693 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4693 miRNA Mature ID miR-4693-3p

miRNA Sequence

UGAGAGUGGAAUUCACAGUAUUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon49

miR-4698 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4698 miRNA Mature ID miR-4698

miRNA Sequence

UCAAAAUGUAGAGGAAGACCCCA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon50

miR-4722 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4722 miRNA Mature ID miR-4722-5p

miRNA Sequence

GGCAGGAGGGCUGUGCCAGGUUG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon51

miR-4728 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-4728 miRNA Mature ID miR-4728-5p

miRNA Sequence

UGGGAGGGGAGAGGCAGCAAGCA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon52

miR-4745 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4745 miRNA Mature ID miR-4745-5p

miRNA Sequence

UGAGUGGGGCUCCCGGGACGGCG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon53

miR-4768 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-4768 miRNA Mature ID miR-4768-3p

miRNA Sequence

CCAGGAGAUCCAGAGAGAAU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon54

miR-485 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-485 miRNA Mature ID miR-485-5p

miRNA Sequence

AGAGGCUGGCCGUGAUGAAUUC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon55

miR-491 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-491 miRNA Mature ID miR-491-5p

miRNA Sequence

AGUGGGGAACCCUUCCAUGAGG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon56

miR-548v directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-548v miRNA Mature ID miR-548v

miRNA Sequence

AGCUACAGUUACUUUUGCACCA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon57

miR-616 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-616 miRNA Mature ID miR-616-5p

miRNA Sequence

ACUCAAAACCCUUCAGUGACUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon58

miR-6165 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6165 miRNA Mature ID miR-6165

miRNA Sequence

CAGCAGGAGGUGAGGGGAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon59

miR-6513 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6513 miRNA Mature ID miR-6513-5p

miRNA Sequence

UUUGGGAUUGACGCCACAUGUCU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon60

miR-665 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-665 miRNA Mature ID miR-665

miRNA Sequence

ACCAGGAGGCUGAGGCCCCU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon61

miR-6736 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6736 miRNA Mature ID miR-6736-3p

miRNA Sequence

UCAGCUCCUCUCUACCCACAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon62

miR-6763 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6763 miRNA Mature ID miR-6763-5p

miRNA Sequence

CUGGGGAGUGGCUGGGGAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon63

miR-6779 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6779 miRNA Mature ID miR-6779-5p

miRNA Sequence

CUGGGAGGGGCUGGGUUUGGC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon64

miR-6780a directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6780a miRNA Mature ID miR-6780a-5p

miRNA Sequence

UUGGGAGGGAAGACAGCUGGAGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon65

miR-6785 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6785 miRNA Mature ID miR-6785-5p

miRNA Sequence

UGGGAGGGCGUGGAUGAUGGUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon66

miR-6787 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6787 miRNA Mature ID miR-6787-3p

miRNA Sequence

UCUCAGCUGCUGCCCUCUCCAG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon67

miR-6788 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6788 miRNA Mature ID miR-6788-5p

miRNA Sequence

CUGGGAGAAGAGUGGUGAAGA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon68

miR-6799 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6799 miRNA Mature ID miR-6799-5p

miRNA Sequence

GGGGAGGUGUGCAGGGCUGG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon69

miR-6825 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6825 miRNA Mature ID miR-6825-5p

miRNA Sequence

UGGGGAGGUGUGGAGUCAGCAU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon70

miR-6851 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-6851 miRNA Mature ID miR-6851-5p

miRNA Sequence

AGGAGGUGGUACUAGGGGCCAGC

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon71

miR-6883 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6883 miRNA Mature ID miR-6883-5p

miRNA Sequence

AGGGAGGGUGUGGUAUGGAUGU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon72

miR-6884 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6884 miRNA Mature ID miR-6884-5p

miRNA Sequence

AGAGGCUGAGAAGGUGAUGUUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon73

miR-6888 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-6888 miRNA Mature ID miR-6888-5p

miRNA Sequence

AAGGAGAUGCUCAGGCAGAU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon74

miR-7106 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-7106 miRNA Mature ID miR-7106-5p

miRNA Sequence

UGGGAGGAGGGGAUCUUGGG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon75

miR-7158 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-7158 miRNA Mature ID miR-7158-3p

miRNA Sequence

CUGAACUAGAGAUUGGGCCCA

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon76

miR-7160 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-7160 miRNA Mature ID miR-7160-5p

miRNA Sequence

UGCUGAGGUCCGGGCUGUGCC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon77

miR-7162 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-7162 miRNA Mature ID miR-7162-3p

miRNA Sequence

UCUGAGGUGGAACAGCAGC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon78

miR-8063 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-8063 miRNA Mature ID miR-8063

miRNA Sequence

UCAAAAUCAGGAGUCGGGGCUU

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon79

miR-887 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-887 miRNA Mature ID miR-887-5p

miRNA Sequence

CUUGGGAGCCCUGUUAGACUC

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon80

miR-890 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-890 miRNA Mature ID miR-890

miRNA Sequence

UACUUGGAAAGGCAUCAGUUG

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)

  Epigenetic Phenomenon81

miR-9 directly targets SLC19A3 [ 20 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-9 miRNA Mature ID miR-9-5p

miRNA Sequence

UCUUUGGUUAUCUAGCUGUAUGA

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon82

miR-939 directly targets SLC19A3 [ 19 ]

Epigenetic Type

microRNA Experiment Method PAR-CLIP

miRNA Stemloop ID

miR-939 miRNA Mature ID miR-939-5p

miRNA Sequence

UGGGGAGCUGAGGCUCUGGGGGUG

miRNA Target Type

Direct

Experimental Material

Multiple cell lines of human

  Epigenetic Phenomenon83

miR-98 directly targets SLC19A3 [ 18 ]

Epigenetic Type

microRNA Experiment Method HITS-CLIP

miRNA Stemloop ID

miR-98 miRNA Mature ID miR-98-5p

miRNA Sequence

UGAGGUAGUAAGUUGUAUUGUU

miRNA Target Type

Direct

Experimental Material

Human embryonic kidney 293 cells (HEK293)
References
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2 Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patients. PLoS One. 2011;6(7):e22233.
3 Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes. Cancer Cell. 2016 Mar 14;29(3):379-393.
4 DNA Methylation Dynamics in Urological Tumors.
5 Genome-wide Scan for Methylation Profiles in Breast Cancer
6 A CpG-methylation-based assay to predict survival in clear cell renal cell carcinoma. Nat Commun. 2015 Oct 30;6:8699.
7 Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics. 2013 Sep;8(9):921-34.
8 Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer. Gastroenterology. 2014 Aug;147(2):418-29.e8.
9 Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips. Epigenetics. 2013 Jan;8(1):34-43.
10 HIV-1 Infection Accelerates Age According to the Epigenetic Clock. J Infect Dis. 2015 Nov 15;212(10):1563-73.
11 DNA methylation analysis of lung adenocarcinoma and adjacent non-tumor tissues
12 Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling. Int J Cancer. 2014 Sep 1;135(5):1110-8.
13 Prognostic Classifier Based on Genome-Wide DNA Methylation Profiling in Well-Differentiated Thyroid Tumors. J Clin Endocrinol Metab. 2017 Nov 1;102(11):4089-4099.
14 Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array. BMC Genomics. 2014 Jan 22;15:51.
15 Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9(8):e1003678.
16 DNA methylation and inflammation marker profiles associated with a history of depression. Hum Mol Genet. 2018 Aug 15;27(16):2840-2850.
17 Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines. Biol Pharm Bull. 2012;35(3):301-7.
18 Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing. Genome Biol. 2013 May 26;14(5):R45.
19 In-depth analysis of the interaction of HIV-1 with cellular microRNA biogenesis and effector mechanisms. MBio. 2013 Apr 16;4(2):e000193.
20 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. Genes Dev. 2013 Jul 15;27(14):1624-32.

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