Detail Information of Disease-specific Protein Abundances
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0103 Transporter Info | ||||
| Gene Name | SLC16A12 | ||||
| Protien Name | Monocarboxylate transporter 12 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Disease-specific Protein Abundances of DT (DPAD) | |||||
|---|---|---|---|---|---|
| ICD-11: 02 Neoplasm | |||||
| [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0005483334544559; Fold-change:inf; Z-score:3.901888015972257 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:8.309299568090238e-07; Fold-change:0.8174997678125897; Z-score:-2.054112537 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:4.982519715289276e-05; Fold-change:0.25; Z-score:-0.751122668 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0009418759084772; Fold-change:0.2068965517241379; Z-score:-1.948354075 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
| [+] ICD-11: 5A11 Type 2 diabetes mellitus | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Islet of langerhans | ||||
| The Specified Disease | Type ii diabetes mellitus [ICD-11:5A11] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0007485356849444; Fold-change:0.5657976412166357; Z-score:-12.38490165 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle | ||||
| The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0172537257217015; Fold-change:1.044968819387747; Z-score:1.695961779759206 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
| [+] ICD-11: 6A02 Autism spectrum disorder | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brain | ||||
| The Specified Disease | Autism [ICD-11:6A02] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1914177778669454; Fold-change:1.6666666666666667; Z-score:1.3176156917368247 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A20 Schizophrenia | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 9 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5337871863155002; Fold-change:0.6666666666666666; Z-score:1.2478692301566603 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_9-1.png)
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_area_9.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 11 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_11-1.png)
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_area_11.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
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_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 9 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_9-1.png)
|
_area_9.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 11 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.926234733267614; Fold-change:2; Z-score:0.0349137742331829 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_11-1.png)
|
_area_11.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5669393956716061; Fold-change:1; Z-score:-0.30429031 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
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_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Dorsolateral prefrontal cortex | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1539023937272612; Fold-change:1.5; Z-score:0.8918524787463777 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 08 Disease of the nervous system | |||||
| [+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Frontal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6008598751956229; Fold-change:0.9698131433060704; Z-score:0.1936222213438651 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Hippocampus | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1306949934276123; Fold-change:1.064006504232368; Z-score:0.8957155252554684 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Temporal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7336189052471522; Fold-change:0.9944696507866116; Z-score:0.1399995695150439 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Muscle | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8298209346580676; Fold-change:1.1232876712328768; Z-score:0.0712529276926473 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myoblast | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8123512285471289; Fold-change:0.68284611141754; Z-score:-0.205760108 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myotube | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2832752674695921; Fold-change:0.4091903719912472; Z-score:-0.723161471 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart left ventricle | ||||
| The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2540135105719848; Fold-change:0.5721343873517787; Z-score:-0.779404194 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 11 Disease of the circulatory system | |||||
| [+] ICD-11: BD10 Congestive heart failure | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle tissue | ||||
| The Specified Disease | Heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3059564301001511; Fold-change:0.7708333333333334; Z-score:-0.51745489 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Left ventricle | ||||
| The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0019561444607113; Fold-change:1.1691579821165945; Z-score:1.4554941260787642 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 13 Disease of the digestive system | |||||
| [+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Ileum | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0265491167962226; Fold-change:1; Z-score:0.5279397519724213 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colonic mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2287782466050329; Fold-change:0.9822166100930092; Z-score:-0.671783017 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Caecum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1520582325565332; Fold-change:1.0865213396667168; Z-score:1.6009096620247238 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Left colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8145111165768786; Fold-change:0.9360551114288918; Z-score:-0.392945415 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Rectum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8135041902553768; Fold-change:0.9823832501382528; Z-score:0.3456943828203527 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Transverse colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8787433224253105; Fold-change:0.9920897404137756; Z-score:0.1433386553319805 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 14 Disease of the skin | |||||
| [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Mouth mucosa | ||||
| The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0784770669539106; Fold-change:0.92185677246067; Z-score:-0.892314009 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:2.4150973975803696e-05; Fold-change:0.2068965517241379; Z-score:-1.956829479 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
| [+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Bone | ||||
| The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0229367238151485; Fold-change:0.97389653585901; Z-score:-0.849967965 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 20 Developmental anomaly | |||||
| [+] ICD-11: LA88.2 Tetralogy of Fallot | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart ventricle | ||||
| The Specified Disease | Tetralogy of fallot [ICD-11:LA88.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0360324904805427; Fold-change:1.9583333333333333; Z-score:1.6439407692102557 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.00 Unicoronal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Coronal craniosynostosis [ICD-11:LB70.00] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3719224891377503; Fold-change:1.5217391304347827; Z-score:1.970006782764448 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.02 Lambdoid craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Lambdoid craniosynostosis [ICD-11:LB70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7385365726975239; Fold-change:1.0434782608695652; Z-score:0.375239387193228 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.03 Metopic craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Metopic craniosynostosis [ICD-11:LB70.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4454652548063318; Fold-change:0.782608695652174; Z-score:-0.712189041 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.0Y Sagittal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Sagittal craniosynostosis [ICD-11:LB70.1] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2385077595730506; Fold-change:1.2173913043478262; Z-score:2.4122532033850383 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0009418759084772; Fold-change:0.2068965517241379; Z-score:-1.948354075 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 25 Codes for special purposes | |||||
| [+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0002154046772953; Fold-change:0.1178743961352657; Z-score:-1.919922767 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colon | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6181836173249455; Fold-change:1.1428571428571428; Z-score:0.3877409877066154 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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