General Information of Drug Transporter (DT)
DT ID DTD0077 Transporter Info
Gene Name SLC10A5
Protien Name Sodium/bile acid cotransporter 5
Gene ID
347051
UniProt ID
Q5PT55
Disease-specific Protein Abundances of DT (DPAD)
ICD-11: 02 Neoplasm
             [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) Click to Show/Hide the Full List
The Studied Tissue Colon
The Specified Disease Colorectal cancer [ICD-11:2B91]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0024450390581239; Fold-change:inf; Z-score:inf
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung Click to Show/Hide the Full List
The Studied Tissue Lung
The Specified Disease Lung adenocarcinoma [ICD-11:2C25]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.318893952263237; Fold-change:0.9871616827959416; Z-score:0.3619386524385312
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung Click to Show/Hide the Full List
The Studied Tissue Lung
The Specified Disease Small cell lung carcinoma [ICD-11:2C25]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.23853659895795; Fold-change:1.5; Z-score:1.1345920655031958
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 2C31 Squamous cell carcinoma of skin Click to Show/Hide the Full List
The Studied Tissue Skin
The Specified Disease Squamous cell carcinoma [ICD-11:2C31.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0008420881117446; Fold-change:0.1276595744680851; Z-score:-1.855929451
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 05 Endocrine, nutritional or metabolic disease
             [+] ICD-11: 5A11 Type 2 diabetes mellitus Click to Show/Hide the Full List
The Studied Tissue Islet of langerhans
The Specified Disease Type ii diabetes mellitus [ICD-11:5A11]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.3810783480820474; Fold-change:0.868421052631579; Z-score:-0.571869639
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 5A14 Diabetes mellitus, type unspecified Click to Show/Hide the Full List
The Studied Tissue Skeletal muscle
The Specified Disease Diabetes mellitus [ICD-11:5A14]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.4961457298389846; Fold-change:1.0099481086136952; Z-score:0.608694528517118
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 06 Mental, behavioural or neurodevelopmental disorder
             [+] ICD-11: 6A02 Autism spectrum disorder Click to Show/Hide the Full List
The Studied Tissue Brain
The Specified Disease Autism [ICD-11:6A02]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0015699034318971; Fold-change:0.3333333333333333; Z-score:-2.282249201
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 6A20 Schizophrenia Click to Show/Hide the Full List
The Studied Tissue Brodmann (1909) area 9
The Specified Disease Schizophrenia [ICD-11:6A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.463652620771865; Fold-change:0.8181818181818182; Z-score:-0.390236164
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Brodmann (1909) area 11
The Specified Disease Schizophrenia [ICD-11:6A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0266455526977712; Fold-change:0.6; Z-score:-0.636267855
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Brodmann (1909) area 24
The Specified Disease Schizophrenia [ICD-11:6A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.2712713353763625; Fold-change:0.3333333333333333; Z-score:-0.592348878
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) Click to Show/Hide the Full List
The Studied Tissue Brodmann (1909) area 9
The Specified Disease Bipolar disorder [ICD-11:6A60]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.9896173746663666; Fold-change:1.2727272727272727; Z-score:0.0092913372462086
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Brodmann (1909) area 11
The Specified Disease Bipolar disorder [ICD-11:6A60]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.1874601266765073; Fold-change:0.8; Z-score:-0.443907806
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Brodmann (1909) area 24
The Specified Disease Bipolar disorder [ICD-11:6A60]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.9475059171692328; Fold-change:1; Z-score:0.0423106341256493
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Dorsolateral prefrontal cortex
The Specified Disease Bipolar disorder [ICD-11:6A60]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.8669135310546305; Fold-change:0.625; Z-score:-0.044775426
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 08 Disease of the nervous system
             [+] ICD-11: 8A20 Alzheimer disease Click to Show/Hide the Full List
The Studied Tissue Frontal cortex
The Specified Disease Alzheimer's disease [ICD-11:8A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.3329072950563911; Fold-change:0.984254450084808; Z-score:-0.379389841
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Hippocampus
The Specified Disease Alzheimer's disease [ICD-11:8A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.3266905059682011; Fold-change:0.9586403597675078; Z-score:-0.648344535
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Temporal cortex
The Specified Disease Alzheimer's disease [ICD-11:8A20]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.157616525960995; Fold-change:0.969824908167178; Z-score:-0.603858229
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy Click to Show/Hide the Full List
The Studied Tissue Muscle
The Specified Disease Facioscapulohumeral dystrophy [ICD-11:8C70.3]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.343123067311079; Fold-change:0.8076923076923077; Z-score:-0.329411462
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Myoblast
The Specified Disease Facioscapulohumeral dystrophy [ICD-11:8C70.3]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.6790280454524651; Fold-change:1.1162790697674418; Z-score:0.4321208107251124
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Myotube
The Specified Disease Facioscapulohumeral dystrophy [ICD-11:8C70.3]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.8621243125480278; Fold-change:0.7; Z-score:0.2309401076758501
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: 8C71.0 Myotonic dystrophy Click to Show/Hide the Full List
The Studied Tissue Heart left ventricle
The Specified Disease Myotonic dystrophy [ICD-11:8C71.0]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.2808409449800291; Fold-change:0.4242424242424242; Z-score:-0.91073888
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 11 Disease of the circulatory system
             [+] ICD-11: BA8Z Diseases of coronary artery, unspecified (coronary artery disease) Click to Show/Hide the Full List
The Studied Tissue Epicardial fat
The Specified Disease Coronary artery disease [ICD-11:BA8Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.4510295570589788; Fold-change:1.0142759363756395; Z-score:0.3907807530611208
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Subcutaneous adipose tissue
The Specified Disease Coronary artery disease [ICD-11:BA8Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.7459743124132716; Fold-change:0.983175859052802; Z-score:-0.177681188
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: BD10 Congestive heart failure Click to Show/Hide the Full List
The Studied Tissue Skeletal muscle tissue
The Specified Disease Heart failure [ICD-11:BD10]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.4304161722237402; Fold-change:0.9166666666666666; Z-score:-0.654653671
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: BD10 Congestive heart failure (post-ischemic) Click to Show/Hide the Full List
The Studied Tissue Left ventricle
The Specified Disease Post ischemic heart failure [ICD-11:BD10]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.908451048316714; Fold-change:1.0046679227135715; Z-score:-0.04328311
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 13 Disease of the digestive system
             [+] ICD-11: DD70 Crohn disease Click to Show/Hide the Full List
The Studied Tissue Ileum
The Specified Disease Crohn's disease [ICD-11:DD70.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0017301736571319; Fold-change:0.5853658536585366; Z-score:-0.520521772
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Colonic mucosa
The Specified Disease Crohn's disease [ICD-11:DD70.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:3.96491123352501e-07; Fold-change:0.847342349439551; Z-score:-5.191135492
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Ileal mucosa
The Specified Disease Crohn's disease [ICD-11:DD70.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0195345895334865; Fold-change:0.9361562179077262; Z-score:-1.057921626
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: DD71 Ulcerative colitis Click to Show/Hide the Full List
The Studied Tissue Caecum
The Specified Disease Active ulcerative colitis [ICD-11:DD71.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.4111073956474306; Fold-change:0.9385433084539322; Z-score:-1.345304815
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Left colon
The Specified Disease Active ulcerative colitis [ICD-11:DD71.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0009010189413777; Fold-change:0.8100385800060399; Z-score:-4.413271137
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Rectum
The Specified Disease Active ulcerative colitis [ICD-11:DD71.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0693269259971931; Fold-change:0.865520660593736; Z-score:-2.075595083
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Transverse colon
The Specified Disease Active ulcerative colitis [ICD-11:DD71.Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0551598036987563; Fold-change:0.8549502957803654; Z-score:-4.666824365
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 14 Disease of the skin
             [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) Click to Show/Hide the Full List
The Studied Tissue Mouth mucosa
The Specified Disease Oral lichen planus [ICD-11:EA91.42]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.473398881860103; Fold-change:0.9369167297706636; Z-score:-0.310372868
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: EK90.0 Actinic keratosis Click to Show/Hide the Full List
The Studied Tissue Skin
The Specified Disease Actinic keratosis [ICD-11:EK90.0]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:8.21993643946114e-05; Fold-change:0.1063829787234042; Z-score:-1.79759899
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 15 Disease of the musculoskeletal system/connective tissue
             [+] ICD-11: FA0Z Osteoarthritis, unspecified site Click to Show/Hide the Full List
The Studied Tissue Bone
The Specified Disease Osteoarthritis [ICD-11:FA0Z]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.067224286913988; Fold-change:1.027823405692258; Z-score:4.602808566600315
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 20 Developmental anomaly
             [+] ICD-11: LA88.2 Tetralogy of Fallot Click to Show/Hide the Full List
The Studied Tissue Heart ventricle
The Specified Disease Tetralogy of fallot [ICD-11:LA88.2]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.2900791685139357; Fold-change:1.25; Z-score:0.7161646460708804
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: LB70.00 Unicoronal craniosynostosis Click to Show/Hide the Full List
The Studied Tissue Skull
The Specified Disease Coronal craniosynostosis [ICD-11:LB70.00]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.166889595816397; Fold-change:0.4545454545454545; Z-score:-1.317465098
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: LB70.02 Lambdoid craniosynostosis Click to Show/Hide the Full List
The Studied Tissue Skull
The Specified Disease Lambdoid craniosynostosis [ICD-11:LB70.3]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0337099148348618; Fold-change:0.3636363636363636; Z-score:-1.903005142
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: LB70.03 Metopic craniosynostosis Click to Show/Hide the Full List
The Studied Tissue Skull
The Specified Disease Metopic craniosynostosis [ICD-11:LB70.2]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.5699527544769816; Fold-change:0.5454545454545454; Z-score:-0.480979322
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: LB70.0Y Sagittal craniosynostosis Click to Show/Hide the Full List
The Studied Tissue Skull
The Specified Disease Sagittal craniosynostosis [ICD-11:LB70.1]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.5642085413932185; Fold-change:0.9090909090909092; Z-score:-0.380601028
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
             [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) Click to Show/Hide the Full List
The Studied Tissue Skin
The Specified Disease Sebaceous of jadassohn nevus [ICD-11:LD2D.Y]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0008420881117446; Fold-change:0.1276595744680851; Z-score:-1.855929451
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
ICD-11: 25 Codes for special purposes
             [+] ICD-11: RA01 COVID-19 Click to Show/Hide the Full List
The Studied Tissue Lung
The Specified Disease Covid [ICD-11:RA01.0]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:0.0248715865486263; Fold-change:0.3392857142857143; Z-score:-0.939989737
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
The Studied Tissue Colon
The Specified Disease Covid [ICD-11:RA01.0]
The Expression Level of Disease Section Compare with the Healthy Individual Tissue p-value:5.7342006118959805e-05; Fold-change:0.0402010050251256; Z-score:-2.082177782
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.