Detail Information of Disease-specific Protein Abundances
General Information of Drug Transporter (DT) | |||||
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DT ID | DTD0077 Transporter Info | ||||
Gene Name | SLC10A5 | ||||
Protien Name | Sodium/bile acid cotransporter 5 | ||||
Gene ID | |||||
UniProt ID |
Disease-specific Protein Abundances of DT (DPAD) | |||||
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ICD-11: 02 Neoplasm | |||||
[+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Colon | ||||
The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0024450390581239; Fold-change:inf; Z-score:inf | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.318893952263237; Fold-change:0.9871616827959416; Z-score:0.3619386524385312 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.23853659895795; Fold-change:1.5; Z-score:1.1345920655031958 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0008420881117446; Fold-change:0.1276595744680851; Z-score:-1.855929451 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
[+] ICD-11: 5A11 Type 2 diabetes mellitus | Click to Show/Hide the Full List | ||||
The Studied Tissue | Islet of langerhans | ||||
The Specified Disease | Type ii diabetes mellitus [ICD-11:5A11] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3810783480820474; Fold-change:0.868421052631579; Z-score:-0.571869639 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skeletal muscle | ||||
The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4961457298389846; Fold-change:1.0099481086136952; Z-score:0.608694528517118 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
[+] ICD-11: 6A02 Autism spectrum disorder | Click to Show/Hide the Full List | ||||
The Studied Tissue | Brain | ||||
The Specified Disease | Autism [ICD-11:6A02] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0015699034318971; Fold-change:0.3333333333333333; Z-score:-2.282249201 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 6A20 Schizophrenia | Click to Show/Hide the Full List | ||||
The Studied Tissue | Brodmann (1909) area 9 | ||||
The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.463652620771865; Fold-change:0.8181818181818182; Z-score:-0.390236164 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Brodmann (1909) area 11 | ||||
The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0266455526977712; Fold-change:0.6; Z-score:-0.636267855 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Brodmann (1909) area 24 | ||||
The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2712713353763625; Fold-change:0.3333333333333333; Z-score:-0.592348878 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Brodmann (1909) area 9 | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9896173746663666; Fold-change:1.2727272727272727; Z-score:0.0092913372462086 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Brodmann (1909) area 11 | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1874601266765073; Fold-change:0.8; Z-score:-0.443907806 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Brodmann (1909) area 24 | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9475059171692328; Fold-change:1; Z-score:0.0423106341256493 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Dorsolateral prefrontal cortex | ||||
The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8669135310546305; Fold-change:0.625; Z-score:-0.044775426 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 08 Disease of the nervous system | |||||
[+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
The Studied Tissue | Frontal cortex | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3329072950563911; Fold-change:0.984254450084808; Z-score:-0.379389841 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Hippocampus | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3266905059682011; Fold-change:0.9586403597675078; Z-score:-0.648344535 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Temporal cortex | ||||
The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.157616525960995; Fold-change:0.969824908167178; Z-score:-0.603858229 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
The Studied Tissue | Muscle | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.343123067311079; Fold-change:0.8076923076923077; Z-score:-0.329411462 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Myoblast | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6790280454524651; Fold-change:1.1162790697674418; Z-score:0.4321208107251124 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Myotube | ||||
The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8621243125480278; Fold-change:0.7; Z-score:0.2309401076758501 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
The Studied Tissue | Heart left ventricle | ||||
The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2808409449800291; Fold-change:0.4242424242424242; Z-score:-0.91073888 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 11 Disease of the circulatory system | |||||
[+] ICD-11: BA8Z Diseases of coronary artery, unspecified (coronary artery disease) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Epicardial fat | ||||
The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4510295570589788; Fold-change:1.0142759363756395; Z-score:0.3907807530611208 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Subcutaneous adipose tissue | ||||
The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7459743124132716; Fold-change:0.983175859052802; Z-score:-0.177681188 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: BD10 Congestive heart failure | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skeletal muscle tissue | ||||
The Specified Disease | Heart failure [ICD-11:BD10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4304161722237402; Fold-change:0.9166666666666666; Z-score:-0.654653671 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Left ventricle | ||||
The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.908451048316714; Fold-change:1.0046679227135715; Z-score:-0.04328311 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 13 Disease of the digestive system | |||||
[+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
The Studied Tissue | Ileum | ||||
The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0017301736571319; Fold-change:0.5853658536585366; Z-score:-0.520521772 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Colonic mucosa | ||||
The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:3.96491123352501e-07; Fold-change:0.847342349439551; Z-score:-5.191135492 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Ileal mucosa | ||||
The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0195345895334865; Fold-change:0.9361562179077262; Z-score:-1.057921626 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Caecum | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4111073956474306; Fold-change:0.9385433084539322; Z-score:-1.345304815 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Left colon | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0009010189413777; Fold-change:0.8100385800060399; Z-score:-4.413271137 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Rectum | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0693269259971931; Fold-change:0.865520660593736; Z-score:-2.075595083 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Transverse colon | ||||
The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0551598036987563; Fold-change:0.8549502957803654; Z-score:-4.666824365 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 14 Disease of the skin | |||||
[+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Mouth mucosa | ||||
The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.473398881860103; Fold-change:0.9369167297706636; Z-score:-0.310372868 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:8.21993643946114e-05; Fold-change:0.1063829787234042; Z-score:-1.79759899 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 15 Disease of the musculoskeletal system/connective tissue | |||||
[+] ICD-11: FA0Z Osteoarthritis, unspecified site | Click to Show/Hide the Full List | ||||
The Studied Tissue | Bone | ||||
The Specified Disease | Osteoarthritis [ICD-11:FA0Z] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.067224286913988; Fold-change:1.027823405692258; Z-score:4.602808566600315 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 20 Developmental anomaly | |||||
[+] ICD-11: LA88.2 Tetralogy of Fallot | Click to Show/Hide the Full List | ||||
The Studied Tissue | Heart ventricle | ||||
The Specified Disease | Tetralogy of fallot [ICD-11:LA88.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2900791685139357; Fold-change:1.25; Z-score:0.7161646460708804 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LB70.00 Unicoronal craniosynostosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skull | ||||
The Specified Disease | Coronal craniosynostosis [ICD-11:LB70.00] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.166889595816397; Fold-change:0.4545454545454545; Z-score:-1.317465098 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LB70.02 Lambdoid craniosynostosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skull | ||||
The Specified Disease | Lambdoid craniosynostosis [ICD-11:LB70.3] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0337099148348618; Fold-change:0.3636363636363636; Z-score:-1.903005142 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LB70.03 Metopic craniosynostosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skull | ||||
The Specified Disease | Metopic craniosynostosis [ICD-11:LB70.2] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5699527544769816; Fold-change:0.5454545454545454; Z-score:-0.480979322 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LB70.0Y Sagittal craniosynostosis | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skull | ||||
The Specified Disease | Sagittal craniosynostosis [ICD-11:LB70.1] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5642085413932185; Fold-change:0.9090909090909092; Z-score:-0.380601028 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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[+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
The Studied Tissue | Skin | ||||
The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0008420881117446; Fold-change:0.1276595744680851; Z-score:-1.855929451 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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ICD-11: 25 Codes for special purposes | |||||
[+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
The Studied Tissue | Lung | ||||
The Specified Disease | Covid [ICD-11:RA01.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0248715865486263; Fold-change:0.3392857142857143; Z-score:-0.939989737 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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The Studied Tissue | Colon | ||||
The Specified Disease | Covid [ICD-11:RA01.0] | ||||
The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:5.7342006118959805e-05; Fold-change:0.0402010050251256; Z-score:-2.082177782 | ||||
DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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