Detail Information of Disease-specific Protein Abundances
| General Information of Drug Transporter (DT) | |||||
|---|---|---|---|---|---|
| DT ID | DTD0037 Transporter Info | ||||
| Gene Name | ABCA10 | ||||
| Protien Name | ATP-binding cassette sub-family A member 10 | ||||
| Gene ID | |||||
| UniProt ID | |||||
| Disease-specific Protein Abundances of DT (DPAD) | |||||
|---|---|---|---|---|---|
| ICD-11: 02 Neoplasm | |||||
| [+] ICD-11: 2B91 Colorectal carcinoma (colorectal cancer) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Colon | ||||
| The Specified Disease | Colorectal cancer [ICD-11:2B91] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0002672343342317; Fold-change:59.5; Z-score:34.491720548610935 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.0 Adenocarcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Lung adenocarcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:3.4789296648898078e-12; Fold-change:0.8200374009334809; Z-score:-1.962843224 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C25.1 Small cell carcinoma of bronchus or lung | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Small cell lung carcinoma [ICD-11:2C25] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0016492931810879; Fold-change:0.2727272727272727; Z-score:-1.405710094 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 2C31 Squamous cell carcinoma of skin | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Squamous cell carcinoma [ICD-11:2C31.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0003688078110757; Fold-change:0.0379746835443038; Z-score:-2.001450356 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 05 Endocrine, nutritional or metabolic disease | |||||
| [+] ICD-11: 5A11 Type 2 diabetes mellitus | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Islet of langerhans | ||||
| The Specified Disease | Type ii diabetes mellitus [ICD-11:5A11] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4083708810604886; Fold-change:0.986842105263158; Z-score:0.7517578334694279 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 5A14 Diabetes mellitus, type unspecified | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle | ||||
| The Specified Disease | Diabetes mellitus [ICD-11:5A14] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.310496118775713; Fold-change:0.9208613013008742; Z-score:-0.58136087 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 06 Mental, behavioural or neurodevelopmental disorder | |||||
| [+] ICD-11: 6A02 Autism spectrum disorder | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brain | ||||
| The Specified Disease | Autism [ICD-11:6A02] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:6.552689206381802e-06; Fold-change:0.2932330827067669; Z-score:-3.985011689 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A20 Schizophrenia | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 9 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8404573674622516; Fold-change:0.96; Z-score:0.1599744061423618 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_9-1.png)
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_area_9.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 11 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2191388804919116; Fold-change:0.9615384615384616; Z-score:-0.491711501 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_11-1.png)
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_area_11.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Schizophrenia [ICD-11:6A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5083987857051515; Fold-change:0.9130434782608696; Z-score:-0.440415165 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
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_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 6A60 Bipolar type I disorder (Bipolar disorder) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Brodmann (1909) area 9 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0978312575371714; Fold-change:0.8; Z-score:-0.954133065 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_9-1.png)
|
_area_9.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 11 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.65919532383266; Fold-change:1.0384615384615383; Z-score:0.3296702106268477 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_11-1.png)
|
_area_11.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Brodmann (1909) area 24 | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9540658491740244; Fold-change:1.0434782608695652; Z-score:-0.041944301 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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_area_24-1.png)
|
_area_24.png) Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Dorsolateral prefrontal cortex | ||||
| The Specified Disease | Bipolar disorder [ICD-11:6A60] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7410979336286084; Fold-change:0.76; Z-score:0.0944392170330291 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 08 Disease of the nervous system | |||||
| [+] ICD-11: 8A20 Alzheimer disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Frontal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9239754947177484; Fold-change:0.990094224605132; Z-score:-0.033474571 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Hippocampus | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2079692098463011; Fold-change:0.977949295485366; Z-score:-0.581933966 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Temporal cortex | ||||
| The Specified Disease | Alzheimer's disease [ICD-11:8A20] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1759100601884569; Fold-change:0.9878710159783484; Z-score:-0.538321624 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C70.3 Facioscapulohumeral muscular dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Muscle | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6228308128307996; Fold-change:0.973655323819978; Z-score:0.1702972431130335 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myoblast | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9640264687688692; Fold-change:0.9444444444444444; Z-score:0.0441941738241592 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Myotube | ||||
| The Specified Disease | Facioscapulohumeral dystrophy [ICD-11:8C70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4855682101204154; Fold-change:3; Z-score:1.0161364737737413 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: 8C71.0 Myotonic dystrophy | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart left ventricle | ||||
| The Specified Disease | Myotonic dystrophy [ICD-11:8C71.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8167544010158294; Fold-change:1.341540404040404; Z-score:0.3736778518485728 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 11 Disease of the circulatory system | |||||
| [+] ICD-11: BA8Z Diseases of coronary artery, unspecified (coronary artery disease) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Epicardial fat | ||||
| The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.2153827294029952; Fold-change:1.009786433982731; Z-score:0.4602955367784203 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Subcutaneous adipose tissue | ||||
| The Specified Disease | Coronary artery disease [ICD-11:BA8Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.4827860279279208; Fold-change:0.992925921948583; Z-score:-0.430433184 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: BD10 Congestive heart failure | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skeletal muscle tissue | ||||
| The Specified Disease | Heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.6721696810514304; Fold-change:1.8115942028985508; Z-score:0.3833907611766342 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: BD10 Congestive heart failure (post-ischemic) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Left ventricle | ||||
| The Specified Disease | Post ischemic heart failure [ICD-11:BD10] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0068424093095785; Fold-change:1.168329256871444; Z-score:1.3079810968292558 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 13 Disease of the digestive system | |||||
| [+] ICD-11: DD70 Crohn disease | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Ileum | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.1875146843841482; Fold-change:0.8176795580110497; Z-score:-0.265826842 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
|
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| The Studied Tissue | Colonic mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0001631512509663; Fold-change:0.877716368509822; Z-score:-1.83246644 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Ileal mucosa | ||||
| The Specified Disease | Crohn's disease [ICD-11:DD70.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.9586132293774514; Fold-change:1.0254751311881425; Z-score:-0.017666987 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: DD71 Ulcerative colitis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Caecum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.3081713628389624; Fold-change:0.8749160360325213; Z-score:-0.807554664 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Left colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0001967219377637; Fold-change:0.753831831497319; Z-score:-12.55057221 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Rectum | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0178547718401981; Fold-change:0.8031499202587964; Z-score:-23.89106847 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Transverse colon | ||||
| The Specified Disease | Active ulcerative colitis [ICD-11:DD71.Z] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0316539729830507; Fold-change:0.8317583643657761; Z-score:-24.68678856 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 14 Disease of the skin | |||||
| [+] ICD-11: EA91 Lichen planus (oral mucosal involvement) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Mouth mucosa | ||||
| The Specified Disease | Oral lichen planus [ICD-11:EA91.42] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5728598438459609; Fold-change:0.97683835720916; Z-score:-0.310627581 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: EK90.0 Actinic keratosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Actinic keratosis [ICD-11:EK90.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:1.1116316123519316e-06; Fold-change:0.0291689598238855; Z-score:-2.011612582 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 20 Developmental anomaly | |||||
| [+] ICD-11: LA88.2 Tetralogy of Fallot | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Heart ventricle | ||||
| The Specified Disease | Tetralogy of fallot [ICD-11:LA88.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8753062486941583; Fold-change:1.293103448275862; Z-score:0.0584012858957911 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.00 Unicoronal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Coronal craniosynostosis [ICD-11:LB70.00] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.7739613734893297; Fold-change:0.9285714285714286; Z-score:0.2645046059469744 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.02 Lambdoid craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Lambdoid craniosynostosis [ICD-11:LB70.3] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.778586739801187; Fold-change:0.7142857142857143; Z-score:0.3174055271363692 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.03 Metopic craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Metopic craniosynostosis [ICD-11:LB70.2] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.5571174252864928; Fold-change:1.2857142857142858; Z-score:0.9219874835865964 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LB70.0Y Sagittal craniosynostosis | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skull | ||||
| The Specified Disease | Sagittal craniosynostosis [ICD-11:LB70.1] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.8049937241893081; Fold-change:0.4285714285714285; Z-score:-0.27508479 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| [+] ICD-11: LC02 Sebaceous naevus (nevus sebaceus of Jadassohn) | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Skin | ||||
| The Specified Disease | Sebaceous of jadassohn nevus [ICD-11:LD2D.Y] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0003688078110757; Fold-change:0.0379746835443038; Z-score:-2.001450356 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| ICD-11: 25 Codes for special purposes | |||||
| [+] ICD-11: RA01 COVID-19 | Click to Show/Hide the Full List | ||||
| The Studied Tissue | Lung | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:5.714016055202876e-05; Fold-change:0.4705221785513756; Z-score:-1.994789963 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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| The Studied Tissue | Colon | ||||
| The Specified Disease | Covid [ICD-11:RA01.0] | ||||
| The Expression Level of Disease Section Compare with the Healthy Individual Tissue | p-value:0.0991107749214887; Fold-change:0.3623853211009174; Z-score:-0.790984612 | ||||
| DT expression in the diseased tissue of patients
DT expression in the normal tissue of healthy individuals
|
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 Please Click the above Thumbnail to View/Download
the Expression Barchart for All Samples
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