Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01497
|
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| Drug Name |
Glycolic acid
|
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| Synonyms |
glycolic acid; 2-Hydroxyacetic acid; hydroxyacetic acid; 79-14-1; Glycollic acid; Hydroxyethanoic acid; Acetic acid, hydroxy-; glycolate; Caswell No. 470; alpha-Hydroxyacetic acid; Kyselina glykolova; Kyselina glykolova [Czech]; Kyselina hydroxyoctova; HOCH2COOH; 2-Hydroxyethanoic acid; Kyselina hydroxyoctova [Czech]; Glycocide; EPA Pesticide Chemical Code 000101; GlyPure; HSDB 5227; NSC 166; Acetic acid, 2-hydroxy-; AI3-15362; UNII-0WT12SX38S; GlyPure 70; BRN 1209322; GLYCOLLATE; C2H4O3; Acetic acid, hydroxy-, homopolymer; EINECS 201-
|
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| Drug Type |
Small molecular drug
|
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| Indication | Melasma [ICD11:ED60.1] | Preclinical | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C2H4O3
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| Canonical SMILES |
C(C(=O)O)O
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| InChI |
InChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
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| InChIKey |
AEMRFAOFKBGASW-UHFFFAOYSA-N
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| CAS Number |
CAS 79-14-1
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| Pharmaceutical Properties | Molecular Weight | 76.05 | Topological Polar Surface Area | 57.5 | ||
| Heavy Atom Count | 5 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 3 | |||
| XLogP |
-1.1
|
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| PubChem CID | ||||||
| PubChem SID |
3460
,6350
,67104
,589599
,623904
,827351
,841751
,3135611
,4523739
,7887947
,8028465
,8137761
,8145512
,8150775
,10536092
,15119621
,24439119
,24847624
,24866341
,24866342
,24869373
,24870413
,24895337
,24898199
,26710336
,26713486
,26717671
,29216298
,29216299
,37336365
,37356959
,37460647
,46508186
,48416874
,48420440
,48423471
,49856273
,51074820
,56355025
,57320457
,57650858
,58106660
,75982826
,81058771
,85086452
,85086453
,85165053
,85244535
,85261655
,87325945
|
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| ChEBI ID |
CHEBI:17497
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | MCT1 | Transporter Info | Monocarboxylate transporter 1 | Substrate | [2] | |
| References | ||||||
| 1 | ClinicalTrials.gov (NCT01976273) A Pilot Study Testing 1064nm Q-switch Laser Versus Glycolic Acid Peels for the Treatment of Melasma | |||||
| 2 | Cidofovir peptide conjugates as prodrugs. Journal of Organometallic Chemistry, 2005, 690(10):2673-2678. | |||||
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