Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01420
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| Drug Name |
N1-methylnicotinamide
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| Synonyms |
Trigonellinamide; 1-methylnicotinamide; N(1)-Methylnicotinamide; N1-Methylnicotinamide; 3-(Aminocarbonyl)-1-methylpyridinium; 1-Methyl nicotinamide; 3-carbamoyl-1-methylpyridinium; 3106-60-3; Pyridinium, 3-carbamoyl-1-methyl-; UNII-UM47085BXC; N(sup 1)-Methylnicotinamide; 3-carbamoyl-1-methylpyridin-1-ium; BRN 3540351; 1-methylpyridine-3-carboxamide; UM47085BXC; CHEBI:16797; 1-methylpyridin-1-ium-3-carboxamide; CHEMBL1209652; Trigonellamide; Pyridinium, 3-(aminocarbonyl)-1-methyl-; 1-methyl-3-carbamoylpyridinium; 8GC; I-methyl n
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| Drug Type |
Small molecular drug
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| Indication | Hypertriglyceridemia [ICD11:5C80.1] | Phase 2 | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C7H9N2O+
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| Canonical SMILES |
C[N+]1=CC=CC(=C1)C(=O)N
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| InChI |
InChI=1S/C7H8N2O/c1-9-4-2-3-6(5-9)7(8)10/h2-5H,1H3,(H-,8,10)/p+1
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| InChIKey |
LDHMAVIPBRSVRG-UHFFFAOYSA-O
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| CAS Number |
CAS 3106-60-3
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| Pharmaceutical Properties | Molecular Weight | 137.16 | Topological Polar Surface Area | 47 | ||
| Heavy Atom Count | 10 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 1 | |||
| XLogP |
-0.1
|
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| PubChem CID | ||||||
| PubChem SID |
2394
,5841
,954035
,5155051
,6555085
,8143645
,8150650
,24438826
,33903490
,48499499
,50033274
,50244387
,56365883
,57320223
,88524034
,103129273
,103268845
,104294886
,107212253
,111677778
,117563530
,124578372
,125672344
,126523494
,127374407
,128423050
,128472654
,135022414
,137136540
,142268689
,142454104
,143405732
,162889726
,163365524
,164817027
,169196253
,178101374
,179293117
,198975697
,223460099
,226500804
,241067449
,243882470
,246430415
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| ChEBI ID |
CHEBI:16797
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | 1-Oct | Transporter Info | Organic cation transporter 1 | Substrate | [2] | |
| References | ||||||
| 1 | ClinicalTrials.gov (NCT00519714) A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA) | |||||
| 2 | Cloning and characterization of two human polyspecific organic cation transporters. DNA Cell Biol. 1997 Jul;16(7):871-81. | |||||
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