Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01412
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| Drug Name |
Glycopyrrolate
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| Synonyms |
GLYCOPYRROLATE; 596-51-0; Glycopyrrolate bromide; Robinul; Gastrodyn; Tarodyl; Nodapton; Tarodyn; Asecryl; Copyrrolate; Cuvposa; Glycopyrronii bromidum; AHR-504; ROBINUL FORTE; Robinal; Robanul; Bromuro de glicopirronio; Bromure de glycopyrronium; NVA-237; AHR 504; Glycopyrronii bromidum [INN-Latin]; EINECS 209-887-0; Bromure de glycopyrronium [INN-French]; Bromuro de glicopirronio [INN-Spanish]; 3-Hydroxy-1,1-dimethylpyrrolidinium bromide
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| Drug Type |
Small molecular drug
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| Indication | Airflow obstruction of chronic obstructive pulmonary disease [ICD11:CA22] | Approved | [1] | |||
| Therapeutic Class |
Anticholinergic Agents
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C19H28BrNO3
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| Canonical SMILES |
C[N+]1(CCC(C1)OC(=O)C(C2CCCC2)(C3=CC=CC=C3)O)C.[Br-]
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| InChI |
InChI=1S/C19H28NO3.BrH/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15;/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3;1H/q+1;/p-1
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| InChIKey |
VPNYRYCIDCJBOM-UHFFFAOYSA-M
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| CAS Number |
CAS 596-51-0
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| Pharmaceutical Properties | Molecular Weight | 398.3 | Topological Polar Surface Area | 46.5 | ||
| Heavy Atom Count | 24 | Rotatable Bond Count | 5 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 4 | |||
| PubChem CID | ||||||
| PubChem SID |
794727
,4582008
,7351415
,8152218
,11466774
,11467894
,11486407
,29222626
,46509133
,47275736
,47720778
,47869842
,48318623
,49699159
,50124171
,57321838
,80767354
,85209742
,103825408
,104234350
,104303677
,117554810
,124893611
,125081928
,127431325
,136023846
,137008742
,141652405
,141652414
,162108778
,162459186
,163366469
,163368548
,179150741
,184685744
,187051762
,224504317
,226501389
,246480751
,247320628
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| ChEBI ID |
CHEBI:90972
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | 1-Oct | Transporter Info | Organic cation transporter 1 | Substrate | [2] | |
| References | ||||||
| 1 | Glycopyrrolate was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | Identification of novel substrates and structure-activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2. J Med Chem. 2013 Sep 26;56(18):7232-42. | |||||
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