Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01397
|
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| Drug Name |
Pyruvic acid
|
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| Synonyms |
BTS; Brenztraubensaeure; Acetylformic acid; Acide pyruvique; Pyroracemic acid; CH3COCOOH; A-Ketopropionic acid; Alpha-Ketopropionic acid; Alpha-Oxopropionsaeure; Alpha-keto propionic acid; Alpha-ketopropionic acid; P-9250; Pyruvic acid (8CI); Pyruvic acid (natural); Propanoic acid, 2-oxo-(9CI); 2-Ketopropionic acid; 2-Oxopropanoate; 2-Oxopropanoic acid; 2-Oxopropansaeure; 2-Oxopropionic acid; 2-Oxopropionsaeure; 2-oxo(1-14c)propanoic acid; 2-oxo-propionic acid
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| Drug Type |
Small molecular drug
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| Indication | Nutritional deficiency [ICD11:5B7Z] | Approved | [1] | |||
| Therapeutic Class |
Dietary supplement
|
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C3H4O3
|
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| Canonical SMILES |
CC(=O)C(=O)O
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| InChI |
InChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
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| InChIKey |
LCTONWCANYUPML-UHFFFAOYSA-N
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| CAS Number |
CAS 127-17-3
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| Pharmaceutical Properties | Molecular Weight | 88.06 | Topological Polar Surface Area | 54.4 | ||
| Heavy Atom Count | 6 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 3 | |||
| XLogP |
-0.3
|
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| PubChem CID | ||||||
| PubChem SID |
3324
,67115
,583760
,821307
,821314
,822632
,823091
,824014
,827046
,832413
,841522
,3134354
,5571669
,6436244
,7850314
,7890146
,8145308
,8150952
,10506205
,11447561
,11528430
,14716341
,14716592
,15194194
,17435687
,22387984
,22389510
,24439413
,24844228
,24846765
,24898862
,24901426
,24901427
,26702717
,26704720
,26707987
,26709793
,26710008
,26714555
,26714561
,29217748
,36487046
,38372743
,46505692
,46520143
,48414842
,49748488
,53789182
,56373996
,56373999
|
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| ChEBI ID |
ChEBI:32816
|
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | MCT1 | Transporter Info | Monocarboxylate transporter 1 | Substrate | [2] | |
| References | ||||||
| 1 | U.S. National Library of Medicine(NLM)-DailyMed | |||||
| 2 | AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Biochem J. 2010 Jan 15;425(3):523-30. | |||||
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