Drug Information

General Information
Drug ID
DR01323
Drug Name
Albendazole
Synonyms
((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle; ((Propylthio)-5 1H-benzimidazolyl-2) carbamate de methyle [French]; (5-(Propylthio)-1H-benzimidazol-2-yl)carbamic acid methyl ester; (5-Propylsulfanyl-1H-benzoimidazol-2-yl)-carbamic acid methyl ester; 5-(Propylthio)-2-carbomethoxyaminobenzimidazole; Albendazol; Albendazol [INN-Spanish]; Albendazole (JAN/USP/INN); Albendazole Armstrong Brand; Albendazole Diba Brand; Albendazole Fustery Brand; Albendazole Hormona Brand; Albendazole Liferpal Brand; Albendazole Monohydrochloride; Albendazole Noe-Socopharm Brand; Albendazole Pfizer Brand; Albendazole Sanicoopa Brand; Albendazole Valdecasas Brand; Albendazole [USAN:INN:BAN:JAN]; Albendazolum; Albendazolum [INN-Latin]; Albendoral; Albenza; Albenza (TN); Albenza, Eskazole, Zentel, Andazol, Albendazole; Armstrong Brand of Albendazole; Bendapar; Bilutac; CARBAMIC ACID, (5-(PROPYLTHIO)-1H-BENZIMIDAZOL-2-YL)-, METHYL ESTER; Carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester; Diba Brand of Albendazole; Digezanol; Disthelm; Disthelm, Mediamix V; Endoplus; Eskazole; Eskazole (TN); Fustery Brand of Albendazole; Gascop; Hormona Brand of Albendazole; Liferpal Brand of Albendazole; Lurdex; Mediamix V Disthelm; Methyl 5-(propyl-thio)-2-benzimidazolecarbamate; Methyl 5-(propylthio)-2-benzimidazolecarbamate; Methyl N-[6-(propylsulfanyl)-1H-1,3-benzodiazol-2-yl]carbamate; Methyl [(2Z)-5-(propylsulfanyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]carbamate; Methyl [5-(Propylthio)benzimidazol-2-yl]carbamate; Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; Methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate; Methyl [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate; Methyl-5-[propylthio]-2-benzimidazole carbamate; MethylN-(6-propylsulfanyl-1H-benzimidazol-2-yl)carbamate; Metiazol; Monohydrochloride, Albendazole; Noe Socopharm Brand of Albendazole; Noe-Socopharm Brand of Albendazole; O-Methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate; Pfizer Brand of Albendazole; Proftril; SK&F 62979; SK&F-62979; SK&F62979; SKF 62979; SKF-62979; SKF62979; Sanicoopa Brand of Albendazole; Smith Kline & French Brand of Albendazole; SmithKline Beecham Brand of Albendazole; V Disthelm, Mediamix; Valbazen; Valdecasas Brand of Albendazole; Zental; Zentel; Zentel (TN); [5-(Propylthio)benzimidazol-2-yl]carbamic Acid Methyl Ester; [5-(Propythio)-1H-benzimidazol-2-yl]carbamic acid methyl ester
Drug Type
Small molecular drug
Indication Parasitic worm infestations [ICD11:1F90] Approved [1]
Therapeutic Class
Antiprotozoal Agents
Structure
3D MOL 2D MOL
Formula
C12H15N3O2S
Canonical SMILES
CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
InChI
InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
InChIKey
HXHWSAZORRCQMX-UHFFFAOYSA-N
CAS Number
CAS 54965-21-8
Pharmaceutical Properties Molecular Weight 265.33 Topological Polar Surface Area 92.3
Heavy Atom Count 18 Rotatable Bond Count 5
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4
XLogP
2.9
PubChem CID
2082
PubChem SID
4909 ,129996 ,603014 ,855809 ,3154181 ,5010055 ,5590332 ,6318023 ,7847202 ,7978654 ,8144956 ,8150054 ,8151416 ,10321635 ,10589336 ,11112790 ,11242363 ,11335879 ,11361118 ,11364426 ,11366988 ,11369550 ,11373940 ,11377712 ,11462090 ,11466275 ,11467395 ,11485989 ,11492016 ,11495346 ,11521860 ,11528637 ,12014008 ,14823901 ,16704067 ,24890894 ,25623359 ,25751296 ,26612535 ,26679872 ,26746999 ,26747000 ,26751522 ,29221262 ,46506472 ,47216788 ,47291149 ,47296872 ,47296873 ,47742180
ChEBI ID
ChEBI:16664
TTD Drug ID
D00KVO
DT(s) Transporting This Drug P-GP Transporter Info P-glycoprotein 1 Substrate [2]
References
1 Albendazole was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019)
2 The anthelminthic agent albendazole does not interact with p-glycoprotein. Drug Metab Dispos. 2002 Apr;30(4):365-9.

If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.