Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01259
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| Drug Name |
Amisulpride
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| Synonyms |
4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-anisamid; 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide; 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide; 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide; Aminosultopride; Amisulpiride; Amisulprida; Amisulprida [INN-Spanish]; Amisulpride (INN); Amisulpride [INN]; Amisulpridum; Amisulpridum [INN-Latin]; DAN 2163; DAN-2163; Deniban; Deniban (TN); SL-91.1077; Socian; Solian; Solian (TN); Solian, Amisulpride
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| Drug Type |
Small molecular drug
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| Indication | Schizophrenia [ICD11:6A20] | Approved | [1] | |||
| Dysthymia [ICD11:6A72] | Approved | [1] | ||||
| Therapeutic Class |
Antipsychotic Agents
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C17H27N3O4S
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| Canonical SMILES |
CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC
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| InChI |
InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
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| InChIKey |
NTJOBXMMWNYJFB-UHFFFAOYSA-N
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| CAS Number |
CAS 53583-79-2
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| Pharmaceutical Properties | Molecular Weight | 369.5 | Topological Polar Surface Area | 110 | ||
| Heavy Atom Count | 25 | Rotatable Bond Count | 7 | |||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 6 | |||
| XLogP |
1.5
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| PubChem CID | ||||||
| PubChem SID |
4426036
,7978690
,8151467
,12013930
,14852985
,24890689
,26719747
,26719748
,26753203
,29221338
,46386656
,46386793
,49681614
,49875487
,50105670
,50740420
,51091647
,56311657
,57321177
,81041117
,81092862
,85208948
,85789065
,90341703
,91746200
,92308440
,92721951
,99437236
,99443244
,103527296
,104299778
,117878946
,121361831
,124658864
,124757136
,124801322
,124891581
,125001904
,125163940
,125312444
,125356672
,126592345
,126618690
,126660738
,126665652
,128751968
,131324616
,131342364
,131480773
,131849879
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| ChEBI ID |
CHEBI:64045
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | P-GP | Transporter Info | P-glycoprotein 1 | Substrate | [2] | |
| References | ||||||
| 1 | AUSTRALIAN PRODUCT INFORMATION SOLIAN (AMISULPRIDE) TABLETS AND SOLUTION | |||||
| 2 | Identification of P-glycoprotein substrates and inhibitors among psychoactive compounds--implications for pharmacokinetics of selected substrates. J Pharm Pharmacol. 2004 Aug;56(8):967-75. | |||||
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