Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR01035
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| Drug Name |
Tetrabenazine
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| Synonyms |
1,3,4,6,7,11b-Hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo(a)quinolizin-2-one; 1,3,4,6,7,11b-Hexahydro-3-isobutyl-9,10-dimethoxy-2H-benzo[a]quinolizin-2-one; 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-Benzo[a]quinolizin-2-one; 2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine; 2-Oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11-beta-hexahydro-2H-benzoquinolizine; 2-Oxo-3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11.beta.-hexahydro-2H-benzoquinolizine; 2H-Benzo(a)quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-(9CI); 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one; 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one; Nitoman; Nitoman (TN); Nitoman, Xenazine, Tetrabenazine; Ro 1-9569; Ro 1-9569/12; Rubigen; Tetra Benazin; Tetrabenazina; Tetrabenazina [INN-Spanish]; Tetrabenazine (INN); Tetrabenazine [INN:BAN]; Tetrabenazinum; Tetrabenazinum [INN-Latin]; Tetrabenzaine; Tetrabenzine; Xenazine; Xenazine (TN)
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Nephropathic cystinosis therapy
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| Structure |
|
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| 3D MOL | 2D MOL | |||||
| Formula |
C19H27NO3
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| Canonical SMILES |
CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1=O)OC)OC
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| InChI |
InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3
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| InChIKey |
MKJIEFSOBYUXJB-UHFFFAOYSA-N
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| CAS Number |
CAS 58-46-8
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| Pharmaceutical Properties | Molecular Weight | 317.4 | Topological Polar Surface Area | 38.8 | ||
| Heavy Atom Count | 23 | Rotatable Bond Count | 4 | |||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 4 | |||
| XLogP |
2.9
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| PubChem CID | ||||||
| PubChem SID |
103928969
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,104310884
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,124671347
,124757499
,125164303
,125205323
,125488233
,126658298
,126687256
,128608402
,13350
,134222085
,134338041
,135588520
,135610686
,135692279
,137248553
,141463478
,14975282
,29216102
,29225032
,442479
,444004
,46506426
,47331537
,49834869
,49890235
,50086515
,51230337
,56311658
,57323119
,5761629
,7914317
,7980763
,81066398
,8153747
,85824684
,90341774
,92291104
,96025259
,99358095
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| TTD Drug ID | ||||||
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