Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00460
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| Drug Name |
Hydrochlorothiazide
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| Synonyms |
3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi; 3,4-Dihydrochlorothiazide; 6-Chloro-7-sulfamoyl-3, 4-dihy; AF-614/30832002; Acesistem; Acuilix; Acuretic; Adiazine-1,1-dioxide; Aldactazide 25/25; Aldazida; Aldectazide 50/50; Aldoril; Apo-Hydro; Apo-Hydro (TN); Apresazide; Aquarills; Aquarius; Aquazide H; Aquazide H (TN); Aquazide-H; Bremil; Briazide; Caplaril; Carozide; Catiazida; Chlorizide; Chlorosulthiadil; Chlorsulfonamidodihydrobenzothiadiazine dioxide; Chlorzide; Chlothia; Cidrex; Clorana; Component of Aldactazide; Component of Aldoril; Component of Butizide Prestabs; Component of Caplaril; Component of Cyclex; Component of Dyazide; Component of Esimil; Concor Plus; Condiuren; Diaqua; Dichlorosal; Dichlorotride; Dichlothiazide; Dichlotiazid; Dichlotride; Dichlotride (TN); Diclot ride; Diclotride; Dicyclotride; Didral; Dihydran; Dihydrochlorothiazid; Dihydrochlorothiazide; Dihydrochlorothiazidum; Dihydrochlorurit; Dihydrochlorurite; Dihydroxychlorothiazidum; Direma; Disalunil; Disothiazid; Diu 25 Vigt; Diu-melusin; Diurogen; Dixidrasi; Drenol; Dro-2H-1,2,4-benzothiadiazine 1,1-dioxide; Esidrex; Esidrex (TN); Esidrix; Esidrix (TN); Esoidrina; Fluvin; H 4759; HCT; HCT-Isis; HCTZ; HCZ; Hidril; Hidro-Niagrin; Hidrochlortiazid; Hidroclorotiazida; Hidroclorotiazida [INN-Spanish]; Hidroronol; Hidrosaluretil; Hidrotiazida; Hyclosid; Hydrex-semi; Hydril; Hydro Par; Hydro-Aquil; Hydro-D; Hydro-Diuril; Hydro-Saluric; Hydro-T; Hydro-chlor; HydroDIURIL; HydroSaluric (TN); Hydrochlorat; Hydrochlorot; Hydrochlorothiazid; Hydrochlorothiazide (JP15/USP/INN); Hydrochlorothiazide Intensol; Hydrochlorothiazide [INN:BAN:JAN]; Hydrochlorothiazidum; Hydrochlorothiazidum [INN-Latin]; Hydrochlorthiazide; Hydrochlorthiazidum; Hydrocot; Hydrodiuretic; Hydrodiuril (TN); Hydropres; Hydrosaluric; Hydrothide; Hydrozide; Hydrozide Injection, Veterinary; Hypothiazid; Hypothiazide; Hytrid; Idroclorotiazide; Idroclorotiazide [DCIT]; Idrotiazide; Inderide 80/25; Indroclor; Ivaugan; Jen-Diril; Lotensin HCT; Manuril; Maschitt; MaybridgeCompound 10; Mazide 25 mg; Medozide; Megadiuril; Microzide; Microzide (TN); Mictrin; Mikorten; Modurcen; Moduretic; Natrinax; Nefrix; Nefrol; Neo-Flumen; Neo-Minzil; Neo-codema; Neoflumen; Newtolide; Novodiurex; Oretic; Oretic (TN); Pantemon; Panurin; Panurin dichloride; Raunova Plus; Ro-hydrazide; Roxane; Saldiuril; Sectrazide; Selozide; Servithiazid; Spironazide; Su 5879; Tandiur; Thiaretic; Thiuretic; Thlaretic; Timolide; Unazid; Urodiazin; Urozide; Vaseretic; Vetidrex
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Diuretics
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C7H8ClN3O4S2
|
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| Canonical SMILES |
C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
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| InChI |
InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
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| InChIKey |
JZUFKLXOESDKRF-UHFFFAOYSA-N
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| CAS Number |
CAS 58-93-5
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| Pharmaceutical Properties | Molecular Weight | 297.7 | Topological Polar Surface Area | 135 | ||
| Heavy Atom Count | 17 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 7 | |||
| XLogP |
-0.1
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| PubChem CID | ||||||
| PubChem SID |
10321359
,103995
,10528484
,10589262
,11111269
,11111270
,11335464
,11360703
,11363771
,11366333
,11368895
,11371452
,11373490
,11377057
,11382607
,11408708
,11461675
,11466037
,11467157
,11484995
,11485674
,11488856
,11490272
,11491821
,11494691
,1434462
,14873640
,16977795
,17389854
,17405176
,220766
,24277806
,24895542
,26611772
,26680075
,26746944
,26746945
,26751473
,29222764
,3159668
,46504440
,46513493
,47216682
,5137564
,7847406
,7979544
,8149374
,8152296
,855646
,9253
|
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| ChEBI ID |
ChEBI:5778
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| TTD Drug ID | ||||||
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