Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00453
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| Drug Name |
Oxcarbazepine
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| Synonyms |
10,11-Dihydro-10-oxo-5H-debenz(b,f)azepine-5-carboxamide; 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide; 10,11-Dihydro-10-oxo-5H-dibenzo[b,f]azepine-5-carboxamide; 10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide; 10-Oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide; 5-oxo-6H-benzo[b][1]benzazepine-11-carboxamide; Desitin brand of oxcarbazepine; Epilexter; Epliga; GP 47680; GP-47680; KIN-493; Novartis brand of oxcarbazepine; O0363; Oxacarbazepine; Oxaleptal (TN); Oxcarbamazepine; Oxcarbazepime; Oxcarbazepina; Oxcarbazepina [INN-Spanish]; Oxcarbazepine (USAN/INN); Oxcarbazepine [INN]; Oxcarbazepinum; Oxcarbazepinum [INN-Latin]; SPN-804; Timox; Trileptal; Trileptal (TN)
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| Drug Type |
Small molecular drug
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| Indication | Epilepsy [ICD11:8A6Z] | Approved | [1] | |||
| Therapeutic Class |
Anticonvulsants
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C15H12N2O2
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| Canonical SMILES |
C1C2=CC=CC=C2N(C3=CC=CC=C3C1=O)C(=O)N
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| InChI |
InChI=1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)
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| InChIKey |
CTRLABGOLIVAIY-UHFFFAOYSA-N
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| CAS Number |
CAS 28721-07-5
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| Pharmaceutical Properties | Molecular Weight | 252.27 | Topological Polar Surface Area | 63.4 | ||
| Heavy Atom Count | 19 | Rotatable Bond Count | 0 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 2 | |||
| XLogP |
1.7
|
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| PubChem CID | ||||||
| PubChem SID |
103292787
,11364569
,11367131
,11369693
,11372776
,11374387
,11377855
,11484081
,11488299
,11491484
,11492449
,11495489
,11528646
,12013820
,15196775
,24724563
,26612687
,26679796
,26719673
,26747194
,26747195
,34676003
,46386767
,46507580
,47291388
,47365462
,50085868
,50105170
,53790510
,57311661
,75522661
,7784956
,7847599
,7980216
,81040908
,81093135
,8173559
,866068
,866523
,87561105
,92124721
,92307920
,92308514
,92309109
,92711414
,93166236
,96099912
,9695
,99233256
,99437127
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| ChEBI ID |
CHEBI:7824
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | P-GP | Transporter Info | P-glycoprotein 1 | Substrate | [2] | |
| References | ||||||
| 1 | Oxcarbazepine was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | The transport of antiepileptic drugs by P-glycoprotein. Adv Drug Deliv Rev. 2012 Jul;64(10):930-42. | |||||
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