Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00445
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| Drug Name |
Voriconazole
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| Synonyms |
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol; (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; (alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; (alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; DRG-0301; Pfizer brand of voriconazole; UK 109,496; UK 109496; UK-109,496; UK-109496; VCZ; VFEND (TN); VRC; Vfend; Vfend, Voriconazole; Voriconazole (JAN/USAN/INN); Voriconazole [USAN:INN:BAN]; Voriconazole in combination with MGCD290
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antifungal Agents
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| Structure |
|
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| 3D MOL | 2D MOL | |||||
| Formula |
C16H14F3N5O
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| Canonical SMILES |
CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O
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| InChI |
InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1
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| InChIKey |
BCEHBSKCWLPMDN-MGPLVRAMSA-N
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| CAS Number |
CAS 137234-62-9
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| Pharmaceutical Properties | Molecular Weight | 349.31 | Topological Polar Surface Area | 76.7 | ||
| Heavy Atom Count | 25 | Rotatable Bond Count | 5 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 8 | |||
| XLogP |
1.5
|
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| PubChem CID | ||||||
| PubChem SID |
103042056
,103188976
,104350892
,109692905
,117510444
,118048601
,12014673
,121361066
,124658937
,124757251
,124766492
,125083219
,125164055
,126592905
,126625471
,126656629
,126670609
,127494461
,134338507
,135029377
,136340251
,136367733
,137006421
,140298163
,144076218
,144205794
,14754154
,14900759
,152164501
,160870955
,160963927
,26719857
,43127923
,46386721
,46506421
,49681678
,49830865
,50065685
,53790739
,57318277
,58107314
,618929
,7847644
,79258320
,8194731
,92308499
,92712543
,93165418
,9824
,99437153
|
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| ChEBI ID |
CHEBI:10023
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| TTD Drug ID | ||||||
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