Drug Information

General Information
Drug ID
DR00434
Drug Name
Fludarabine
Synonyms
(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-F-ara-A; 2-Fluoro Ara-A; 2-Fluoro-9-beta-D-arabinofuranosyladenine; 9-beta-D-Arabinofuranosyl-2-fluoroadenine; 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine; 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-(9CI); F-Ara-A; FaraA; Fludara, Fludarabine; Fludarabina; Fludarabina [Spanish]; Fludarabine (INN); Fludarabine [INN]; Fludarabinum; Fludarabinum [Latin]; Fluradosa; Fluradosa (TN); SQ Fludarabine
Drug Type
Small molecular drug
Therapeutic Class
Anticancer Agents
Structure
3D MOL 2D MOL
Formula
C10H12FN5O4
Canonical SMILES
C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N
InChI
InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
InChIKey
HBUBKKRHXORPQB-FJFJXFQQSA-N
CAS Number
CAS 75607-67-9
Pharmaceutical Properties Molecular Weight 285.23 Topological Polar Surface Area 140
Heavy Atom Count 20 Rotatable Bond Count 2
Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 9
XLogP
-0.6
PubChem CID
657237
PubChem SID
103588722 ,104170131 ,113529123 ,117527505 ,118048763 ,12015425 ,121362454 ,123121326 ,124757293 ,124800219 ,125164097 ,128038069 ,130399360 ,131378849 ,134994031 ,135684141 ,135697967 ,135723536 ,136342497 ,136367939 ,136375530 ,137000684 ,141858050 ,144115985 ,144206348 ,144206969 ,14751067 ,151994330 ,152055900 ,15222429 ,152344067 ,162011966 ,162036224 ,163072527 ,164216431 ,166831392 ,170464764 ,172080756 ,49865029 ,53790210 ,56310845 ,57408458 ,71840321 ,74951141 ,7979234 ,855645 ,9268240 ,96024661 ,99437182 ,99453172
ChEBI ID
ChEBI:94701
TTD Drug ID
D0F2XQ

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