Drug Information

General Information
Drug ID
DR00417
Drug Name
Dexrazoxane
Synonyms
(+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane; (+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; (S)-(+)-1,2-Bis(3,5-dioxopiperazin-1-yl)propane; 2,6-Piperazinedione, 4,4'-(1-methyl-1,2-ethanediyl)bis-, (+)-(9CI); 4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione; 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione; 4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione hydrochloride; ADR 529; Cardioxane; Cardioxane (TN); Desrazoxane; Dexrazoxane (TN); Dexrazoxane (USAN/INN); Dexrazoxane HCl; Dexrazoxane [USAN:BAN:INN]; Dexrazoxane hydrochloride; Dexrazoxano; Dexrazoxano [INN-Spanish]; Dexrazoxanum; Dexrazoxanum [INN-Latin]; Dextrorazoxane; Dyzoxane; Eucardion; ICRF 187; ICRF 187 hydrochloride; ICRF-187; Razoxane, (S)-Isomer; Savene; Soluble ICRF (L-isosomer); TopoTect; Totect; Totect (TN); Totect, ICRF-187, Zinecard, Cardioxane, Dexrazoxane Hydrochloride;(+)-(S)-4,4'-Propylenedi-2,6-piperazinedione; Zinecard; Zinecard (TN)
Drug Type
Small molecular drug
Therapeutic Class
Anticancer Agents
Structure
3D MOL 2D MOL
Formula
C11H16N4O4
Canonical SMILES
CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2
InChI
InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKey
BMKDZUISNHGIBY-ZETCQYMHSA-N
CAS Number
CAS 24584-09-6
Pharmaceutical Properties Molecular Weight 268.27 Topological Polar Surface Area 98.8
Heavy Atom Count 19 Rotatable Bond Count 3
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6
XLogP
-1.4
PubChem CID
71384
PubChem SID
103693192 ,104350333 ,11405762 ,117600767 ,126670108 ,127536650 ,131307062 ,134337939 ,135029834 ,136376430 ,137002682 ,137241718 ,141868796 ,144205809 ,14774896 ,14872576 ,152035811 ,160812421 ,160871504 ,160963727 ,162174646 ,163089322 ,170464709 ,172080045 ,172092159 ,172860861 ,17397819 ,174007392 ,174476563 ,174560588 ,175266611 ,176484596 ,176484943 ,177748989 ,178103902 ,179117166 ,184816244 ,198945773 ,43127718 ,442425 ,46505982 ,46506541 ,50012896 ,50139412 ,57318172 ,75683665 ,8194593 ,831389 ,93166226 ,93619796
ChEBI ID
ChEBI:50223
TTD Drug ID
D07XVN

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