Drug Information

General Information
Drug ID
DR00247
Drug Name
Vasopressin
Synonyms
ADH (hormone); American Pharmaceutical Brand of Vasopressin; American Regent Brand of Vasopressin; Antidiuretic Hormones; Antidiuretic hormone; Beta Hypophamine; Beta-Hypophamine; Inyectable de vasopresina; Inyectable de vasopresina [INN-Spanish]; Leiormone; Monarch Brand of Vasopressin; Parke-Davis Brand of Vasopressin (USP); Pitressin; Pitressin (TN); Pituitrin; Solute injectable de vasopressine; Solute injectable de vasopressine [INN-French]; Tonephin; Vasopressin (JP15/USP); Vasopressin (USP); Vasopressin Monarch Brand; Vasopressin injection; Vasopressina; Vasopressina [DCIT]; Vasopressine; Vasopressini injectio; Vasopressini injectio [INN-Latin]; Vasopressins; Vasopressinum
Drug Type
Small molecular drug
Indication Diabetes [ICD11:5A10-5A14] Approved [1]
Enuresis [ICD11:6C00] Approved [1]
Polyuria [ICD11:MF55] Approved [1]
Therapeutic Class
Vasoconstrictor Agents
Structure
3D MOL 2D MOL
Formula
C46H65N15O12S2
Canonical SMILES
C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)N
InChI
InChI=1S/C46H65N15O12S2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1
InChIKey
KBZOIRJILGZLEJ-LGYYRGKSSA-N
CAS Number
CAS 11000-17-2
Pharmaceutical Properties Molecular Weight 1084.2 Topological Polar Surface Area 515
Heavy Atom Count 75 Rotatable Bond Count 19
Hydrogen Bond Donor Count 14 Hydrogen Bond Acceptor Count 16
XLogP
-4.8
PubChem CID
644077
PubChem SID
104083701 ,109827448 ,134974187 ,135651625 ,140377228 ,144206588 ,15411997 ,160650127 ,162254868 ,163312391 ,163346232 ,17397139 ,179694497 ,223435346 ,226427648 ,246709883 ,249582977 ,29218064 ,43765812 ,50111753 ,53789769 ,57408192 ,74876209 ,7980875 ,841489 ,85856460 ,99313696
ChEBI ID
CHEBI:34543
TTD Drug ID
D0N4OW
DT(s) Transporting This Drug MRP2 Transporter Info Multidrug resistance-associated protein 2 Substrate [2]
References
1 Vasopressin was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019)
2 Transport function and hepatocellular localization of mrp6 in rat liver. Mol Pharmacol. 2000 Mar;57(3):634-41.

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