Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00245
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| Drug Name |
Clopidogrel
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| Synonyms |
Clopidogrel (captisol-enabled); Clopidogrel (captisol-enabled), The Medicines Co; Clopidogrel (captisol-enabled, cardiovascular disease), Cydex; Clopidogrel (captisol-enabled, cardiovascular disease), Prism Pharmaceuticals; PM-103
|
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| Drug Type |
Small molecular drug
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| Indication | Thrombosis [ICD11:BD71.4, BD72] | Approved | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C16H16ClNO2S
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| Canonical SMILES |
COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3
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| InChI |
InChI=1S/C16H16ClNO2S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14/h2-5,7,9,15H,6,8,10H2,1H3/t15-/m0/s1
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| InChIKey |
GKTWGGQPFAXNFI-HNNXBMFYSA-N
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| CAS Number |
CAS 113665-84-2
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| Pharmaceutical Properties | Molecular Weight | 321.8 | Topological Polar Surface Area | 57.8 | ||
| Heavy Atom Count | 21 | Rotatable Bond Count | 4 | |||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 4 | |||
| XLogP |
3.8
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| PubChem CID | ||||||
| PubChem SID |
103724173
,104153271
,104170201
,104178839
,104321200
,11335962
,11361201
,11362959
,11365521
,11368083
,11372530
,11373828
,11376245
,11462173
,11484199
,11488328
,11491421
,11491990
,11493919
,117481059
,117776384
,121362382
,14899359
,14923888
,43117983
,46507295
,47365229
,48035158
,48415808
,49666065
,49666423
,49830418
,50064182
,50111396
,50139266
,50300054
,51092025
,56320467
,7978975
,8150041
,8186960
,85787400
,89736084
,92309297
,92309332
,92717149
,93166442
,93625433
,99301875
,99309408
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| ChEBI ID |
CHEBI:37941
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | P-GP | Transporter Info | P-glycoprotein 1 | Substrate | [2] | |
| References | ||||||
| 1 | Clopidogrel was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | Impact of P-glycoprotein on clopidogrel absorption. Clin Pharmacol Ther. 2006 Nov;80(5):486-501. | |||||
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