Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00202
|
|||||
| Drug Name |
D-mannose
|
|||||
| Synonyms |
Mannose
|
|||||
| Drug Type |
Small molecular drug
|
|||||
| Indication | Urinary tract infections [ICD11:GC08] | Phase 4 | [1] | |||
| Structure |
|
 |
||||
| 3D MOL | 2D MOL | |||||
| Formula |
C6H12O6
|
|||||
| Canonical SMILES |
C(C1C(C(C(C(O1)O)O)O)O)O
|
|||||
| InChI |
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6?/m1/s1
|
|||||
| InChIKey |
WQZGKKKJIJFFOK-QTVWNMPRSA-N
|
|||||
| CAS Number |
CAS 530-26-7
|
|||||
| Pharmaceutical Properties | Molecular Weight | 180.16 | Topological Polar Surface Area | 110 | ||
| Heavy Atom Count | 12 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 5 | Hydrogen Bond Acceptor Count | 6 | |||
| XLogP |
-2.6
|
|||||
| PubChem CID | ||||||
| PubChem SID |
103583168
,104346557
,124801461
,125310805
,126523054
,126631771
,127844171
,129621449
,131317572
,131465283
,134228441
,134228449
,134958993
,134984714
,134999617
,135136220
,137002180
,139416018
,14720290
,15066909
,15322061
,22396012
,24277482
,24882738
,24882739
,24896601
,24897068
,26737907
,29217866
,29286577
,3135279
,3459
,53788969
,56311267
,56320690
,56323500
,56475044
,57330235
,57651949
,79376412
,8027205
,8164149
,824810
,838927
,85164870
,87572161
,91700886
,92298697
,92710545
,93375117
|
|||||
| ChEBI ID |
ChEBI:4208
|
|||||
| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | SGLT4 | Transporter Info | Sodium/glucose cotransporter 4 | Substrate | [2] | |
| References | ||||||
| 1 | ClinicalTrials.gov (NCT03497598) Preventing Recurrent Urinary Tract Infections With -D-mannose | |||||
| 2 | SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose. Life Sci. 2005 Jan 14;76(9):1039-50. | |||||
If you find any error in data or bug in web service, please kindly report it to Dr. Li and Dr. Fu.