Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00167
|
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| Drug Name |
Taurine
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| Synonyms |
.beta.-Aminoethylsulfonic acid; 1-Aminoethane-2-sulfonic acid; 107-35-7; 1EQV5MLY3D; 2-Aminoethylsulfonic acid; 2-Sulfoethylamine; 2-aminoethane-1-sulfonic acid; 2-aminoethanesulfonic acid; AI3-18307; Aminoethanesulfonic acid; CCRIS 4721; CHEBI:15891; EINECS 203-483-8; Ethanesulfonic acid, 2-amino-; FEMA No. 3813; L-Taurine; NCI-C60606; NSC 32428; NSC32428; O-Due; Taurina [Spanish]; Taurine [INN]; Taurinum [Latin]; UNII-1EQV5MLY3D; aminoethylsulfonic acid; beta-Aminoethylsulfonic acid; taufon; tauphon
|
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| Drug Type |
Small molecular drug
|
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| Indication | Congestive heart failure [ICD11:BD10] | Phase 4 | [1] | |||
| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C2H7NO3S
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| Canonical SMILES |
C(CS(=O)(=O)O)N
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| InChI |
InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)
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| InChIKey |
XOAAWQZATWQOTB-UHFFFAOYSA-N
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| CAS Number |
CAS 107-35-7
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| Pharmaceutical Properties | Molecular Weight | 125.15 | Topological Polar Surface Area | 88.8 | ||
| Heavy Atom Count | 7 | Rotatable Bond Count | 2 | |||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 4 | |||
| XLogP |
-4.1
|
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| PubChem CID | ||||||
| PubChem SID |
10503452
,11111855
,11113407
,11407207
,15146560
,17389723
,17405690
,24278721
,24439473
,24888584
,24888585
,24900217
,24900552
,24901890
,26751645
,3136598
,3544
,37402452
,46500351
,46506189
,4656526
,47515475
,48414494
,48423589
,48425250
,49830281
,49854645
,50104337
,50104338
,53778240
,53789289
,56320736
,56320737
,57320751
,57653091
,608224
,7847115
,7890685
,7980729
,8027993
,80818340
,81059398
,8138146
,8145091
,8150985
,820951
,821198
,841390
,855439
,90924
|
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| ChEBI ID |
CHEBI:15891
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | TAUT | Transporter Info | Sodium- and chloride-dependent taurine transporter | Substrate | [2] | |
| References | ||||||
| 1 | ClinicalTrials.gov (NCT02344719) Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosis | |||||
| 2 | Astrocytic -aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain. 2018 Feb;113:1-7. | |||||
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