Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00165
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| Drug Name |
D-glucose
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| Synonyms |
(3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol; 2280-44-6; CPC hydrate; Cartose Cerelose; Clearsweet 95; Clintose L; D-Glc; D-Glcp; D-Glucopyranose; D-Glucopyranose, anhydrous; D-Glucopyranoside; D-glucose-ring; DSSTox_CID_2910; EINECS 218-914-5; Glc; Glc-OH; Glucodin; Glucopyranose; Glucopyranose, D-; Glucopyranoside; Glucose 40; Glucose solution; Meritose; Meritose 200; Roferose ST; Staleydex 130; Staleydex 95M; glc-ring
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| Drug Type |
Small molecular drug
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| Indication | Hypoglycemia [ICD11:5A21; 5A41] | Approved | [1] | |||
| Structure |
|
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| 3D MOL | 2D MOL | |||||
| Formula |
C6H12O6
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| Canonical SMILES |
C(C1C(C(C(C(O1)O)O)O)O)O
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| InChI |
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6?/m1/s1
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| InChIKey |
WQZGKKKJIJFFOK-GASJEMHNSA-N
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| CAS Number |
CAS 2280-44-6
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| Pharmaceutical Properties | Molecular Weight | 180.16 | Topological Polar Surface Area | 110 | ||
| Heavy Atom Count | 12 | Rotatable Bond Count | 1 | |||
| Hydrogen Bond Donor Count | 5 | Hydrogen Bond Acceptor Count | 6 | |||
| XLogP |
-2.6
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| PubChem CID | ||||||
| PubChem SID |
103825436
,104243011
,104310274
,117392201
,117689413
,126523020
,126678536
,127264014
,127264015
,127264016
,127264017
,127264018
,127264019
,127264020
,127264021
,14720288
,15120604
,15147309
,22387980
,22396026
,29218051
,29224827
,3333
,40439603
,48415870
,48416720
,56311091
,56311268
,56311363
,56311402
,56311555
,56311961
,56312072
,56314074
,56314202
,56314360
,56475096
,7847077
,79376410
,8023353
,8153564
,819111
,823016
,823057
,833240
,838951
,841535
,85267087
,85301111
,87570266
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| ChEBI ID |
ChEBI:4167
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | GLUT1 | Transporter Info | Glucose transporter type 1 | Substrate | [2] | |
| SGLT2 | Transporter Info | Sodium/glucose cotransporter 2 | Substrate | [3] | ||
| References | ||||||
| 1 | D-glucose was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | The SLC2 (GLUT) family of membrane transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):121-38. | |||||
| 3 | The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing. PLoS One. 2014 Feb 26;9(2):e89977. | |||||
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