Drug Information

General Information
Drug ID
DR00151
Drug Name
Pomalidomide
Synonyms
Actimid (TN); Pomalidomide (Immunomodulator)
Drug Type
Small molecular drug
Indication Systemic sclerosis [ICD11:4A42.0] Approved [1]
Structure
3D MOL 2D MOL
Formula
C13H11N3O4
Canonical SMILES
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
InChI
InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)
InChIKey
UVSMNLNDYGZFPF-UHFFFAOYSA-N
CAS Number
CAS 19171-19-8
Pharmaceutical Properties Molecular Weight 273.24 Topological Polar Surface Area 110
Heavy Atom Count 20 Rotatable Bond Count 1
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 5
XLogP
0.2
PubChem CID
134780
PubChem SID
10243744 ,103100612 ,103221733 ,104253216 ,104382952 ,117621779 ,124757341 ,125164145 ,125697093 ,129427476 ,135089995 ,135727444 ,136348254 ,136367549 ,136946644 ,137009922 ,142523166 ,143499180 ,14848461 ,149539643 ,152235120 ,152258286 ,152343904 ,160647125 ,160837107 ,162011791 ,162012270 ,162037668 ,162189531 ,162856472 ,163398415 ,163778934 ,163907985 ,164194051 ,172889447 ,172889448 ,173130995 ,174007398 ,174528127 ,175424471 ,175427148 ,178103920 ,179116970 ,186007045 ,29312424 ,50086901 ,50447747 ,53787052 ,57345004 ,96025659
ChEBI ID
ChEBI:72690
TTD Drug ID
D0A3ZU
DT(s) Transporting This Drug P-GP Transporter Info P-glycoprotein 1 Substrate [2]
References
1 Pomalidomide was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019)
2 DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. (ID: DB08910)

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