Drug Information

General Information
Drug ID
DR00100
Drug Name
Adenosine monophosphate
Synonyms
(S)-1-C-(7-Amino-1H-pyrazolo(4,3-d)pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 5-(dihydrogen phosphate); 1H-Pyrazolo(4,3-d)pyrimidine, 7-amino-3-beta-D-ribofuranosyl-, 5'-(dihydrogen phosphate)-, hydrate; 5'-AMP; 5'-Adenylic acid, homopolymer; 5'-Deoxy-5'-thioadenosine 5'-monophosphate; 5'-O-phosphonatoadenosine; 5'-O-phosphonoadenosine; 5'-Thio-5'-adenylic acid; 5'-adenosine monophosphate; 5'-adenylic acid; 7-Amino-3-beta-D-ribofuranosyl-1H-pyrazolo(4,3-d)pyrimidine 5'-(dihydrogen phosphate) hydrate; 7A8E6D15-9136-44C1-88C9-E1A224638E56; 7gpb; 8-Aminoadenosine 5'-monophosphate; 8gpb; A-5mp; ADENOSINE-5'-PHOSPHATE; AMP; AMP (VAN); AMP (nucleotide); AMP dianion; ASMP; Adenine polynucleotides; Adenosine 5'-(dihydrogen phosphate); Adenosine 5'-monophosphate; Adenosine 5'-monophosphoric acid; Adenosine 5'-phosphate; Adenosine 5'-phosphoric acid; Adenosine Monophosphate (Amp); Adenosine phosphate; Adenosine phosphate (USAN/INN); Adenosine phosphate [USAN:BAN:INN]; Adenosine phosphate [USAN:INN:BAN]; Adenosine, mono(dihydrogen phosphate) (ester); Adenosine-5'-monophosphate; Adenosine-5'-monophosphoric acid; Adenosine-5'P; Adenosine-5-monophosphate dianion; Adenosine-5-monophosphate(2-); Adenosine-5-monophosphoric acid; Adenosine-5-phosphate; Adenosine-monophosphate; Adenosine-phosphate; Adenosini phosphas; Adenosini phosphas [INN-Latin]; Adenovite; Adenyl; Adenyl (TN);Adenylic acid (VAN); Adenylate; Adenylic acid; Ado5'P; Cardiomone; Ergadenylic acid; Formycin 5'-monophosphate hydrate; Formycin 5'-phosphate; Formycin 5'-phosphate hydrate; Formycin A 5'-monophosphate hydrate; Fosfato de adenosina; Fosfato de adenosina [INN-Spanish]; GAMMA-ARSONO-BETA, GAMMA-METHYLENEADENOSINE-5'-DIPHOSPHATE; Lycedan; Monophosphadenine; Muscle adenylic acid; Muskeladenosin-phosphorsaeure; Muskeladenylsaeure; My-B-Den; Myoston; PAdo; POLY A; Phosaden; Phosphaden; Phosphate d'adenosine; Phosphate d'adenosine [INN-French]; Phosphentaside; Polyadenylic acids; Vitamin B8; [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Drug Type
Small molecular drug
Indication Dietary shortage [ICD11:5B7Z] Approved [1]
Therapeutic Class
Dietary supplement
Structure
3D MOL 2D MOL
Formula
C10H14N5O7P
Canonical SMILES
C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O)N
InChI
InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKey
UDMBCSSLTHHNCD-KQYNXXCUSA-N
CAS Number
CAS 61-19-8
Pharmaceutical Properties Molecular Weight 347.22 Topological Polar Surface Area 186
Heavy Atom Count 23 Rotatable Bond Count 4
Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 11
XLogP
-3.5
PubChem CID
6083
PubChem SID
3322 ,583720 ,583923 ,584440 ,584442 ,584452 ,584455 ,584487 ,584571 ,585427 ,610407 ,819401 ,819945 ,819947 ,819949 ,820210 ,820387 ,820906 ,821396 ,823646 ,823841 ,824145 ,824148 ,826522 ,826525 ,826568 ,826569 ,827049 ,827589 ,827693 ,827918 ,828361 ,828365 ,828366 ,828368 ,828899 ,830720 ,830875 ,832127 ,832329 ,832477 ,832865 ,833689 ,834616 ,836112 ,837134 ,838177 ,838245 ,838945 ,841545
ChEBI ID
ChEBI:16027
TTD Drug ID
D06ACW
DT(s) Transporting This Drug PMP34 Transporter Info Peroxisomal membrane protein PMP34 Substrate [2]
Drug-Transporter Activity Data
Drug-Transporter Activity Data PMP34 Transporter Info Km =190 microM Human liver cancer cells (HepG2)-PMP34 [2]
References
1 Bitter blocker backed by FDA
2 The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+. Biochem J. 2012 Apr 1;443(1):241-7.

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