Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00098
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| Drug Name |
Glucose-6-phosphate
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| Synonyms |
299-31-0; 6-O-phosphono-D-glucopyranose; AC1L1LI0; AC1Q28E3; CHEBI:4170; D-Glucopyranose 6-phosphoric acid; D-glucopyranose 6-phosphate; D-glucopyranose, 6-(dihydrogen phosphate); D-glucose-6-P; D-glucose-6P; GTPL4647; Glc6P; Glucose 6-(dihydrogen phosphate); Glucose 6-phosphate; Robison ester; SCHEMBL48379; a-D-glucose 6- phosphate; {[(2R,3S,4S,5R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid
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| Drug Type |
Small molecular drug
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| Indication | High blood glucose [ICD11:5C61.5] | Phase 1 | [1] | |||
| Structure |
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| 3D MOL | 2D MOL | |||||
| Formula |
C6H13O9P
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| Canonical SMILES |
C(C1C(C(C(C(O1)O)O)O)O)OP(=O)(O)O
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| InChI |
InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5-,6?/m1/s1
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| InChIKey |
NBSCHQHZLSJFNQ-GASJEMHNSA-N
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| CAS Number |
CAS 56-73-5
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| Pharmaceutical Properties | Molecular Weight | 260.14 | Topological Polar Surface Area | 157 | ||
| Heavy Atom Count | 16 | Rotatable Bond Count | 3 | |||
| Hydrogen Bond Donor Count | 6 | Hydrogen Bond Acceptor Count | 9 | |||
| XLogP |
-4.2
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| PubChem CID | ||||||
| PubChem SID | ||||||
| ChEBI ID |
ChEBI:4170
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | G3PP | Transporter Info | Glycerol-3-phosphate permease | Substrate | [2] | |
| G6PT | Transporter Info | Glucose-6-phosphate translocase | Substrate | [3] | ||
| References | ||||||
| 1 | ClinicalTrials.gov (NCT01205178) G6PD (Glucose-6-phosphate Dehydrogenase) Study to Evaluate Hemolysis Potential of TFQ (Tafenoquine) | |||||
| 2 | SLC37A1 and SLC37A2 are phosphate-linked, glucose-6-phosphate antiporters. PLoS One. 2011;6(9):e23157. | |||||
| 3 | A novel mutation (A148V) in the glucose 6-phosphate translocase (SLC37A4) gene in a Korean patient with glycogen storage disease type 1b. J Korean Med Sci. 2005 Jun;20(3):499-501. | |||||
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