Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00088
|
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| Drug Name |
Tramadol
|
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| Synonyms |
Conzip; Rybix Odt; Ryzolt; Tramadol Hydrochloride; Ultram; Ultram Er
|
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| Drug Type |
Small molecular drug
|
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| Indication | Pain [ICD11:MG30-MG7Z] | Approved | [1] | |||
| Therapeutic Class |
Analgesics
|
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C16H25NO2
|
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| Canonical SMILES |
CN(C)CC1CCCCC1(C2=CC(=CC=C2)OC)O
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| InChI |
InChI=1S/C16H25NO2/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3
|
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| InChIKey |
TVYLLZQTGLZFBW-UHFFFAOYSA-N
|
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| CAS Number |
CAS 27203-92-5
|
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| Pharmaceutical Properties | Molecular Weight | 263.37 | Topological Polar Surface Area | 32.7 | ||
| Heavy Atom Count | 19 | Rotatable Bond Count | 4 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 3 | |||
| XLogP |
2.6
|
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| PubChem CID | ||||||
| PubChem SID |
103113054
,104309473
,117617520
,123083206
,125679912
,126682485
,129321889
,134995846
,135060961
,137010486
,142192184
,15221636
,162831124
,164174929
,164765703
,164765706
,179225203
,184526607
,184596120
,216106831
,223656715
,223766038
,226439878
,241058775
,244533735
,249923528
,252166498
,29224565
,49958171
,49958172
,49958173
,50837838
,5658598
,8153398
,85209685
|
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| ChEBI ID |
CHEBI:75722
|
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | P-GP | Transporter Info | P-glycoprotein 1 | Substrate | [2] | |
| References | ||||||
| 1 | Tramadol was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
| 2 | Tramadol hydrochloride: pharmacokinetics, pharmacodynamics, adverse side effects, co-administration of drugs and new drug delivery systems. Biomed Pharmacother. 2015 Mar;70:234-8. | |||||
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