Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00048
|
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| Drug Name |
Urea
|
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| Drug Type |
Small molecular drug
|
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| Indication | Dermatological disease [ICD11:EA00-EM0Z] | Preclinical | [1] | |||
| Structure |
|
 |
||||
| 3D MOL | 2D MOL | |||||
| Formula |
CH4N2O
|
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| Canonical SMILES |
C(=O)(N)N
|
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| InChI |
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
|
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| InChIKey |
XSQUKJJJFZCRTK-UHFFFAOYSA-N
|
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| CAS Number |
CAS 57-13-6
|
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| Pharmaceutical Properties | Molecular Weight | 60.056 | Topological Polar Surface Area | 69.1 | ||
| Heavy Atom Count | 4 | Rotatable Bond Count | 0 | |||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 1 | |||
| XLogP |
-1.4
|
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| PubChem CID | ||||||
| PubChem SID |
10527796
,11110202
,11110234
,11335261
,11360500
,11363566
,11366128
,11368690
,11372940
,11374913
,11376852
,11461472
,11484999
,11489008
,11491606
,11492982
,11494486
,14709415
,15146258
,17389689
,17435981
,17435984
,17436160
,24424275
,24424281
,24439525
,24858038
,24859899
,24873567
,24873568
,24873571
,24873573
,24873763
,3134850
,3274
,3386
,5426301
,584817
,589705
,599346
,7847091
,7891021
,8007365
,8144973
,8149579
,8151011
,838465
,841412
,855226
,92014
|
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| ChEBI ID |
CHEBI:16199
|
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| TTD Drug ID | ||||||
| DT(s) Transporting This Drug | OATP1A2 | Transporter Info | Organic anion transporting polypeptide 1A2 | Substrate | [2] | |
| References | ||||||
| 1 | Wikipedia: Urea | |||||
| 2 | Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters. Exp Hematol. 2011 Apr;39(4):446-56. | |||||
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