Drug Information
General Information | ||||||
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Drug ID |
DR00020
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Drug Name |
L-tyrosine
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Synonyms |
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid; (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid; (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid; (S)-2-Amino-3-(p-hydroxyphenyl)propionic acid; (S)-3-(p-Hydroxyphenyl)alanine; (S)-Tyrosine; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; 2-Amino-3-(p-hydroxyphenyl)propionic acid; 3-(4-Hydroxyphenyl)-L-alanine; 3-(p-Hydroxyphenyl)alanine; 4-Hydroxy-L-phenylalanine; 4ts1; Alpha-Amino-beta-(4-hydroxyphenyl)propionic acid; Beta-(p-Hydroxyphenyl)alanine; DD69927C-C6A8-4BC6-8E9A-0AB423B176E7; DTY; Free-Form L-Tyrosine; H-Tyr-OH; L-(-)-Tyrosine; L-2-Amino-3-p-hydroxyphenylpropanoic acid; L-Tyrosin; L-Tyrosine (9CI); L-Tyrosine (JAN); L-Tyrosine hydrochloride; L-Tyrosine, homopolymer; L-Tyrosine, monomer; L-p-Tyrosine; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide, <3 kd fraction; Melanin synthesized from Tyr substrate catalyzed by tyrosinase, brominated with N-bromosuccinimide; Melanin synthesized from Tyr substrate catalyzed by tyrosinase, sulfonated using sulfur trioxide/DMF complex for 1.5-7 hours; P-Tyrosine; Rxosine; TYR NH3+ COOH; Tirosina; Tirosina [Spanish]; Tyr; Tyrosine; Tyrosine (USP/INN); Tyrosine (VAN); Tyrosine Power; Tyrosine [USAN:INN]; Tyrosine, L-(8CI); Tyrosinum; Tyrosinum [Latin]
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Drug Type |
Small molecular drug
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Indication | Dietary shortage [ICD11:5B7Z] | Approved | [1] | |||
Therapeutic Class |
Dietary supplement
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Structure |
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3D MOL | 2D MOL | |||||
Formula |
C9H11NO3
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Canonical SMILES |
C1=CC(=CC=C1CC(C(=O)O)N)O
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InChI |
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
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InChIKey |
OUYCCCASQSFEME-QMMMGPOBSA-N
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CAS Number |
CAS 60-18-4
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Pharmaceutical Properties | Molecular Weight | 181.19 | Topological Polar Surface Area | 83.6 | ||
Heavy Atom Count | 13 | Rotatable Bond Count | 3 | |||
Hydrogen Bond Donor Count | 3 | Hydrogen Bond Acceptor Count | 4 | |||
XLogP |
-2.3
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PubChem CID | ||||||
PubChem SID |
10529154
,11528398
,14710671
,15147336
,15195185
,24697644
,24697646
,24889931
,24900164
,24900206
,24900543
,24901863
,25622129
,26702499
,26711663
,26711664
,26711665
,26718889
,26719042
,29215265
,29215266
,29225067
,3134840
,3382
,46394031
,46394400
,46504669
,46507885
,48416689
,585619
,585656
,608132
,7847090
,7887220
,7890924
,8026808
,8028352
,8028353
,8144790
,8153780
,817482
,817486
,817487
,817488
,817489
,823160
,828554
,832231
,841729
,854649
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ChEBI ID |
ChEBI:17895
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TTD Drug ID | ||||||
DT(s) Transporting This Drug | LAT2 | Transporter Info | L-type amino acid transporter 2 | Substrate | [2] | |
References | ||||||
1 | L-tyrosine was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019) | |||||
2 | The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.3.8.20) |
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