General Information
Drug ID
DR00020
Drug Name
L-tyrosine
Synonyms
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid; (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid; (S)-2-Amino-3-(4-hydroxyphenyl)propionic acid; (S)-2-Amino-3-(p-hydroxyphenyl)propionic acid; (S)-3-(p-Hydroxyphenyl)alanine; (S)-Tyrosine; (S)-alpha-Amino-4-hydroxybenzenepropanoic acid; 2-Amino-3-(p-hydroxyphenyl)propionic acid; 3-(4-Hydroxyphenyl)-L-alanine; 3-(p-Hydroxyphenyl)alanine; 4-Hydroxy-L-phenylalanine; 4ts1; Alpha-Amino-beta-(4-hydroxyphenyl)propionic acid; Beta-(p-Hydroxyphenyl)alanine; DD69927C-C6A8-4BC6-8E9A-0AB423B176E7; DTY; Free-Form L-Tyrosine; H-Tyr-OH; L-(-)-Tyrosine; L-2-Amino-3-p-hydroxyphenylpropanoic acid; L-Tyrosin; L-Tyrosine (9CI); L-Tyrosine (JAN); L-Tyrosine hydrochloride; L-Tyrosine, homopolymer; L-Tyrosine, monomer; L-p-Tyrosine; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide; Melanin synthesized from Tyr substrate catalyzed by tyrosinase for 6 hrs, oxidized with hydrogen peroxide, <3 kd fraction; Melanin synthesized from Tyr substrate catalyzed by tyrosinase, brominated with N-bromosuccinimide; Melanin synthesized from Tyr substrate catalyzed by tyrosinase, sulfonated using sulfur trioxide/DMF complex for 1.5-7 hours; P-Tyrosine; Rxosine; TYR NH3+ COOH; Tirosina; Tirosina [Spanish]; Tyr; Tyrosine; Tyrosine (USP/INN); Tyrosine (VAN); Tyrosine Power; Tyrosine [USAN:INN]; Tyrosine, L-(8CI); Tyrosinum; Tyrosinum [Latin]
Drug Type
Small molecular drug
Indication Dietary shortage [ICD11:5B7Z] Approved [1]
Therapeutic Class
Dietary supplement
Structure
3D MOL 2D MOL
Formula
C9H11NO3
Canonical SMILES
C1=CC(=CC=C1CC(C(=O)O)N)O
InChI
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChIKey
OUYCCCASQSFEME-QMMMGPOBSA-N
CAS Number
CAS 60-18-4
Pharmaceutical Properties Molecular Weight 181.19 Topological Polar Surface Area 83.6
Heavy Atom Count 13 Rotatable Bond Count 3
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 4
XLogP
-2.3
PubChem CID
6057
PubChem SID
10529154 ,11528398 ,14710671 ,15147336 ,15195185 ,24697644 ,24697646 ,24889931 ,24900164 ,24900206 ,24900543 ,24901863 ,25622129 ,26702499 ,26711663 ,26711664 ,26711665 ,26718889 ,26719042 ,29215265 ,29215266 ,29225067 ,3134840 ,3382 ,46394031 ,46394400 ,46504669 ,46507885 ,48416689 ,585619 ,585656 ,608132 ,7847090 ,7887220 ,7890924 ,8026808 ,8028352 ,8028353 ,8144790 ,8153780 ,817482 ,817486 ,817487 ,817488 ,817489 ,823160 ,828554 ,832231 ,841729 ,854649
ChEBI ID
ChEBI:17895
TTD Drug ID
D01CRB
DT(s) Transporting This Drug LAT2 Transporter Info L-type amino acid transporter 2 Substrate [2]
References
1 L-tyrosine was approved by FDA. The official website of the U.S. Food and Drug Administration. (2019)
2 The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 4;44(D1):D372-9. (ID: 2.A.3.8.20)

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