Drug Information

General Information
Drug ID
DR00700
Drug Name
Ezogabine
Synonyms
ADD-230001; Carbamic acid, (2-amino-4-(((4-fluorophenyl)methyl)amino)phenyl)-, ethyl ester; D 20443; D 23129; D-20443; D-23129; Ethyl (2-amino-4-(((4-fluorophenyl)methyl)amino)phenyl)carbamate; Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate; Ethyl N-(2-amino-4-(4-fluorobenzylamino)phenyl)carbamate hydrochloride; Ethyl N-[2-amino-4-[(4-fluorophenyl)methylamino]phenyl]carbamate; Ezogabine; GKE-841; KE-0201; N-(2-Amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester; N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester; Potiga; Retigabine [USAN]; Trobalt; [2-Amino-4-[[(4-fluorophenyl)methyl]amino]phenyl]-carbamate
Drug Type
Small molecular drug
Therapeutic Class
Anticonvulsants
Structure
3D MOL 2D MOL
Formula
C16H18FN3O2
Canonical SMILES
CCOC(=O)NC1=C(C=C(C=C1)NCC2=CC=C(C=C2)F)N
InChI
InChI=1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
InChIKey
PCOBBVZJEWWZFR-UHFFFAOYSA-N
CAS Number
CAS 150812-12-7
Pharmaceutical Properties Molecular Weight 303.33 Topological Polar Surface Area 76.4
Heavy Atom Count 22 Rotatable Bond Count 6
Hydrogen Bond Donor Count 3 Hydrogen Bond Acceptor Count 5
XLogP
2.8
PubChem CID
121892
PubChem SID
10239851 ,103220716 ,103875964 ,104032719 ,104414526 ,118046799 ,118855330 ,12015005 ,124490309 ,125341609 ,126623656 ,126655065 ,126665918 ,128896436 ,131299831 ,134338628 ,135077118 ,135650896 ,136345679 ,136920410 ,136946473 ,137156938 ,141970640 ,14800601 ,152034730 ,152159608 ,160645840 ,162011781 ,162205078 ,163123042 ,163620909 ,163686230 ,164042455 ,164194995 ,164233343 ,164786707 ,174006313 ,174527464 ,24263039 ,29302387 ,49898865 ,50233601 ,53788352 ,57339830 ,58107328 ,85174557 ,85202062 ,854071 ,91615883 ,92715048
TTD Drug ID
D0X7GL

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