Drug Information

General Information
Drug ID
DR00631
Drug Name
Quinapril
Synonyms
(3S)-2-(N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxylic acid; (3S)-2-{(2S)-2-[(1S)-1-ethoxycarbonyl-3-phenylpropylamino]propanoyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (3S)-2-{N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; Accupril (TN); Ectren; Koretic; QUINAPRIL HCL; Quinapril (USP/INN); Quinapril [INN:BAN]; Quinaprilum; Quinaprilum [Latin]; [3S-[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-Isoquinolinecarboxylic acid
Drug Type
Small molecular drug
Therapeutic Class
Antihypertensive Agents
Structure
3D MOL 2D MOL
Formula
C25H30N2O5
Canonical SMILES
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC=CC=C3CC2C(=O)O
InChI
InChI=1S/C25H30N2O5/c1-3-32-25(31)21(14-13-18-9-5-4-6-10-18)26-17(2)23(28)27-16-20-12-8-7-11-19(20)15-22(27)24(29)30/h4-12,17,21-22,26H,3,13-16H2,1-2H3,(H,29,30)/t17-,21-,22-/m0/s1
InChIKey
JSDRRTOADPPCHY-HSQYWUDLSA-N
CAS Number
CAS 85441-61-8
Pharmaceutical Properties Molecular Weight 438.5 Topological Polar Surface Area 95.9
Heavy Atom Count 32 Rotatable Bond Count 10
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6
XLogP
1.2
PubChem CID
54892
PubChem SID
103590286 ,104306102 ,11335885 ,11361124 ,11364491 ,11367053 ,11369615 ,11372621 ,11374133 ,11377777 ,11462096 ,11484485 ,11488641 ,11491366 ,11492542 ,11495411 ,117576967 ,121264493 ,124893433 ,126683866 ,127334979 ,127334980 ,127334981 ,127334982 ,127334983 ,127334984 ,127334985 ,14759220 ,14881354 ,17397841 ,34718828 ,46506309 ,47589015 ,48035134 ,48259244 ,48416506 ,49835285 ,50065313 ,50113005 ,50113006 ,50744269 ,7980446 ,8145927 ,8149893 ,8183841 ,85787397 ,92309221 ,93166955 ,9602 ,99301798
ChEBI ID
ChEBI:8713
TTD Drug ID
D0I7SZ

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