Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00609
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| Drug Name |
Spironolactone
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| Synonyms |
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate; 7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone; 7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone; Abbolactone; Acelat; Aldace; Aldactazide; Aldactazide (TN); Aldactide; Aldactone; Aldactone (TN); Aldactone A; Alderon; Aldopur; Almatol; Alphapharm Brand of Spironolactone; Alpharma Brand of Spironolactone; Alter Brand of Spironolactone; Altex; Aquareduct; Ashbourne Brand of Spironolactone; Azupharma Brand of Spironolactone; Berlactone (TN); Betapharm Brand of Spironolactone; Cardel Brand of Spironolactone; Ct Arzneimittel Brand of Spironolactone; Ct-Arzneimittel Brand of Spironolactone; Deverol; Dexo Brand of Spironolactone; Diatensec; Dira; Duraspiron; Espironolactona; Espironolactona Alter; Espironolactona Mundogen; Espironolactona [INN-Spanish]; Euteberol; Flumach; Frumikal; Generosan Brand of Spironolactone; Hormosan Brand of Spironolactone; Jenapharm Brand of Spironolactone; Jenaspiron; LT00772287; Lacalmin; Lacdene; Laractone; Mayoly-Spindler Brand of Spironolactone; Melarcon; Merck dura Brand of Spironolactone; Mundogen Brand of Spironolactone; Nefurofan; Novo Spiroton; Novo-Spiroton; Novo-Spiroton (TN); NovoSpiroton; Novopharm Brand of Spironolactone; Osyrol; Pfizer Brand of Spironolactone; Pharmafrid Brand of Spironolactone; Practon; Roche Brand of Spironolactone; SC 9420; SC-9420; SC9420; SNL; Sagisal; Searle Brand of Spironolactone; Sincomen; Spiractin; Spiractin (TN); Spiresis; Spiretic; Spiridon; Spiro L.U.T.; Spiro von ct; Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan); Spiro-Tablinen; Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]; Spirobeta; Spiroctan; Spiroctanie; Spiroderm; Spirogamma; Spirolactone; Spirolakton; Spirolang; Spirolone; Spirone; Spirono Isis; Spirono-Isis; Spironocompren; Spironolactone (JP15/USP/INN); Spironolactone A; Spironolactone [BAN:INN:JAN]; Spironolactone [INN:BAN:JAN]; Spironolactonum; Spironolactonum [INN-Latin]; Spironolattone; Spironolattone [DCIT]; Spironone; Spirospare; Spirotone (TN); Sprioderm; Supra-puren; Suracton; Uractone; Urusonin; Veroshpiron; Verospiron; Verospiron (TN); Verospirone; Verospirone Opianin; Von ct, spiro; Worwag Brand of Spironolactone; Xenalon
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Diuretics
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| Structure |
|
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| 3D MOL | 2D MOL | |||||
| Formula |
C24H32O4S
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| Canonical SMILES |
CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C
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| InChI |
InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
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| InChIKey |
LXMSZDCAJNLERA-ZHYRCANASA-N
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| CAS Number |
CAS 52-01-7
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| Pharmaceutical Properties | Molecular Weight | 416.6 | Topological Polar Surface Area | 85.7 | ||
| Heavy Atom Count | 29 | Rotatable Bond Count | 2 | |||
| Hydrogen Bond Donor Count | 0 | Hydrogen Bond Acceptor Count | 5 | |||
| XLogP |
2.9
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| PubChem CID | ||||||
| PubChem SID |
103469419
,103913949
,104097735
,11466156
,11467276
,11485851
,12157539
,14782265
,14855731
,22395181
,24277736
,26717209
,26757816
,29204585
,29224866
,3138746
,431586
,46508525
,47193741
,47277003
,47500920
,48020409
,48244799
,49699055
,50019597
,50111676
,50928797
,53788778
,56314087
,56320673
,56320674
,56352940
,56462986
,57288839
,57322990
,6436731
,7847509
,7890527
,7980649
,8153601
,83591809
,85787487
,87575785
,92125142
,92309277
,92711407
,93167089
,93576647
,93619777
,9518
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| ChEBI ID |
ChEBI:9241
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| TTD Drug ID | ||||||
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