Drug Information

General Information
Drug ID
DR00565
Drug Name
Sildenafil
Synonyms
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine; 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate; 5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one; 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one (Sildenafil or Viagra); 5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one(Sildenafil); 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one; 5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; 5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Aphrodil; Aphrodil (TN); Revatio (TN); Sildenafil (INN); Sildenafil [INN:BAN]; UK-92,480-10; UK-92480; VIA; Viagra (TN)
Drug Type
Small molecular drug
Therapeutic Class
Antiimpotence Agents
Structure
3D MOL 2D MOL
Formula
C22H30N6O4S
Canonical SMILES
CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C
InChI
InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
InChIKey
BNRNXUUZRGQAQC-UHFFFAOYSA-N
CAS Number
CAS 139755-83-2
Pharmaceutical Properties Molecular Weight 474.6 Topological Polar Surface Area 118
Heavy Atom Count 33 Rotatable Bond Count 7
Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 8
XLogP
1.5
PubChem CID
135398744
PubChem SID
11342069 ,11362252 ,11364449 ,11367011 ,11369573 ,11373023 ,11374191 ,11377735 ,11485511 ,11487654 ,11489464 ,11491707 ,11492401 ,11495369 ,11528697 ,14834479 ,14883184 ,26612617 ,26680877 ,26748898 ,26748899 ,29215463 ,29224269 ,4075716 ,4368414 ,46393303 ,46393579 ,46394222 ,46508371 ,46514731 ,47810856 ,48259349 ,48416538 ,4980084 ,50085897 ,50416042 ,53786977 ,56313704 ,56322606 ,57322656 ,585744 ,61212546 ,7980598 ,81040866 ,8153203 ,832888 ,85248200 ,85788522 ,89736128 ,9468
TTD Drug ID
D0Z7ZM

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