Drug Information

General Information
Drug ID
DR00563
Drug Name
Amlodipine
Synonyms
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl); 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester; 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester; 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; 3-Ethyl-5-methyl (+/-)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; 3-Ethyl-5-methyl (-)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat; 3-Ethyl-5-methyl (-)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; 3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; AMLODIPINE BASE; Amlocard; Amlodipine (INN); Amlodipine Free Base; Amlodipine [INN:BAN]; Amlodipino; Amlodipino [Spanish]; Amlodipinum; Amlodipinum [Latin]; Amlodis; Amlopres; Amlor; Coroval; Dailyvasc (TN); Intervask; Istin (TN); Lipinox; Norvasc (TN); Perivasc (TN); R,S)-Amlodipine; Racemic Amlodipine; UK-4834011
Drug Type
Small molecular drug
Therapeutic Class
Antihypertensive Agents
Structure
3D MOL 2D MOL
Formula
C20H25ClN2O5
Canonical SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
InChI
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3
InChIKey
HTIQEAQVCYTUBX-UHFFFAOYSA-N
CAS Number
CAS 88150-42-9
Pharmaceutical Properties Molecular Weight 408.9 Topological Polar Surface Area 99.9
Heavy Atom Count 28 Rotatable Bond Count 10
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 7
XLogP
3
PubChem CID
2162
PubChem SID
104234246 ,104299787 ,11372046 ,11374781 ,11484087 ,11488302 ,11490819 ,11492946 ,117436332 ,119525879 ,12013616 ,124360696 ,124659134 ,124757688 ,124799862 ,124893198 ,124893199 ,125164492 ,125336819 ,125359103 ,126525316 ,14781768 ,29217715 ,29221341 ,4436379 ,46386686 ,46507214 ,47730753 ,47730754 ,48415556 ,49681578 ,50032146 ,50111725 ,50111726 ,50946098 ,51091781 ,53787488 ,56313574 ,57321180 ,7978692 ,8151470 ,85175495 ,85789496 ,85789660 ,87322623 ,9043 ,92308659 ,92308823 ,92711323 ,93166968
TTD Drug ID
D08JIV

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