Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00549
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| Drug Name |
Troglitazone
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| Synonyms |
(+-)-all-rac-5-(p-((6-Hydroxy-2,5,7,8-tetramethyl-2-chromanyl)methoxy)benzyl)-2,4-thiazolidinedione; (+/-)-5-[4-[(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy]benzyl]-2,4-thiazolidinedione; 2,4-Thiazolidinedione, 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-(9CI); 5-(4-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl-methoxy)benzyl)-2,4-thiazolidinedione); 5-(4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)thiazolidine-2,4-dione; 5-[(4-{[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methyl]oxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione; 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione; 5-[[4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydrochromen-2-yl)methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione; 5-{4-[(6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy]benzyl}-1,3-thiazolidine-2,4-dione; CS 045; CS-045; GR 92132X; GR-92132X; Noscal; Parke Davis brand of troglitazone; Prelay; Resulin; Resulin (TN); Rezulin; Rezulin (TN); Romglizone; Romozin; Romozin (TN); Troglitazona; Troglitazone (JAN/USAN/INN); Troglitazone [USAN:BAN:INN]; Troglitazonum; Warner-Lambert brand of troglitazone
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antiinflammatory Agents
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| Structure |
|
 |
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| 3D MOL | 2D MOL | |||||
| Formula |
C24H27NO5S
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| Canonical SMILES |
CC1=C(C2=C(CCC(O2)(C)COC3=CC=C(C=C3)CC4C(=O)NC(=O)S4)C(=C1O)C)C
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| InChI |
InChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,19,26H,9-12H2,1-4H3,(H,25,27,28)
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| InChIKey |
GXPHKUHSUJUWKP-UHFFFAOYSA-N
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| CAS Number |
CAS 97322-87-7
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| Pharmaceutical Properties | Molecular Weight | 441.5 | Topological Polar Surface Area | 110 | ||
| Heavy Atom Count | 31 | Rotatable Bond Count | 5 | |||
| Hydrogen Bond Donor Count | 2 | Hydrogen Bond Acceptor Count | 6 | |||
| XLogP |
5.1
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| PubChem CID | ||||||
| PubChem SID |
103164301
,103853949
,104309674
,104829539
,11533348
,119526104
,12013560
,124892345
,124892346
,124892347
,124892348
,125334732
,126647230
,126683373
,14905963
,22391425
,24724629
,26681461
,26755242
,26755243
,26757864
,26759664
,29216382
,29224629
,46487963
,46504655
,47365443
,47811013
,48035383
,48416678
,4894294
,50052241
,53788686
,56311256
,56312004
,56313972
,56313996
,57288866
,57322861
,74940595
,7847461
,7980843
,8153443
,841060
,85246179
,85257254
,85787118
,91011836
,92307894
,92308758
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| ChEBI ID |
ChEBI:9753
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| TTD Drug ID | ||||||
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