Drug Information
| General Information | ||||||
|---|---|---|---|---|---|---|
| Drug ID |
DR00516
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| Drug Name |
Doxazosin
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| Synonyms |
1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin; 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[4-(1,4-benzodioxan-2-yl)carpiperazin-1-yl)]-6,7-dimethoxyquinazoline mesylate; 2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-bis(methyloxy)quinazolin-4-amine; 2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine; 2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine; Cardura (TN); Cardura XL (TN); Cardura-1; Cardura-2; Cardura-4; Carduran (TN); Doxazosin (INN); Doxazosin [INN:BAN]; Doxazosina; Doxazosina [Spanish]; Doxazosine; Doxazosine [French]; Doxazosinum; Doxazosinum [Latin]; Normothen; UK 33274; UK-33274; [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
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| Drug Type |
Small molecular drug
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| Therapeutic Class |
Antihypertensive Agents
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| Structure |
|
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| 3D MOL | 2D MOL | |||||
| Formula |
C23H25N5O5
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| Canonical SMILES |
COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC
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| InChI |
InChI=1S/C23H25N5O5/c1-30-18-11-14-15(12-19(18)31-2)25-23(26-21(14)24)28-9-7-27(8-10-28)22(29)20-13-32-16-5-3-4-6-17(16)33-20/h3-6,11-12,20H,7-10,13H2,1-2H3,(H2,24,25,26)
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| InChIKey |
RUZYUOTYCVRMRZ-UHFFFAOYSA-N
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| CAS Number |
CAS 74191-85-8
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| Pharmaceutical Properties | Molecular Weight | 451.5 | Topological Polar Surface Area | 112 | ||
| Heavy Atom Count | 33 | Rotatable Bond Count | 4 | |||
| Hydrogen Bond Donor Count | 1 | Hydrogen Bond Acceptor Count | 9 | |||
| XLogP |
2.5
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| PubChem CID | ||||||
| PubChem SID |
103194429
,103930616
,104170183
,104302690
,106228658
,11222167
,11466886
,11468006
,11486532
,117488203
,117498461
,121362602
,124671348
,124883381
,124883382
,124883384
,125357054
,14784191
,24278398
,29222299
,4407398
,46506825
,47298998
,47298999
,47299000
,47670375
,47744452
,47744453
,47818609
,48415923
,49698667
,50011218
,50105246
,50308562
,56311128
,56311129
,56313874
,56464101
,57321640
,7979127
,8152011
,85209457
,85787347
,90341261
,90342475
,9184
,92241035
,92309056
,92710466
,96024570
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| ChEBI ID |
ChEBI:4708
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| TTD Drug ID | ||||||
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