Drug Information

General Information
Drug ID
DR00483
Drug Name
Azelastine
Synonyms
4-((4-Chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone hydrochloride; 4-((4-chlorophenyl)methyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1(2H)-phthalazinone HCl; 4-(4-chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one; 4-(p-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone; 4-(p-chlorobenzyl)-2-(N-methylperhydroazepinyl-(4))-1-(2H)-phthalazinone; 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one; 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one; Astelin (TN); Astepro (TN); Azelastina; Azelastina [INN-Spanish]; Azelastine (INN); Azelastine [INN:BAN]; Azelastinum; Azelastinum [INN-Latin]; Optivar; Optivar (TN)
Drug Type
Small molecular drug
Therapeutic Class
Antiallergic Agents
Structure
3D MOL 2D MOL
Formula
C22H24ClN3O
Canonical SMILES
CN1CCCC(CC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl
InChI
InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3
InChIKey
MBUVEWMHONZEQD-UHFFFAOYSA-N
CAS Number
CAS 58581-89-8
Pharmaceutical Properties Molecular Weight 381.9 Topological Polar Surface Area 35.9
Heavy Atom Count 27 Rotatable Bond Count 3
Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 3
XLogP
4.4
PubChem CID
2267
PubChem SID
103188977 ,104300096 ,11373087 ,11484393 ,11488465 ,11491799 ,124893571 ,125353726 ,126686074 ,128573214 ,131344384 ,134337644 ,135027355 ,137175390 ,139157643 ,14829436 ,152034299 ,160964310 ,162173200 ,162876873 ,163414086 ,164788079 ,164833138 ,172912872 ,174007265 ,176485063 ,178103698 ,179116569 ,179499903 ,184643901 ,210279616 ,210281939 ,29221440 ,4503340 ,46507582 ,47953967 ,48415598 ,50010207 ,50122563 ,50854757 ,51091808 ,57321230 ,7978748 ,81040982 ,8151525 ,85209838 ,85788529 ,87245030 ,87350406 ,9970
TTD Drug ID
D00JVR

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