Drug Information

General Information
Drug ID
DR00323
Drug Name
Budesonide
Synonyms
(11-beta,16-alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione; (11beta,16alpha)-16,17-(Butylidenebis(oxy))-11,21-dihydroxypregna-1,4-diene-3,20-dione; (4aR,4bS,5S,6aS,6bS,8R,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-8-propyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one; (R,S)-11b,16a,17,21,tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with buty raldehyde; (RS)-(11beta,16alpha)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione; (RS)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with butyraldehyde; (S)-16alpha,17-(Butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; 11beta,21-dihydroxy-16alpha,17alpha-(butane-1,1-diyldioxy)pregna-1,4-diene-3,20-dione; 16,17-Butylidenebis(oxy)-11,21-dihydroxypregna-1,4-diene-3,20-dione; 16,17-Butylidenebis(oxy)-11-,21-dihydroxypregna-1,4-diene-3,20-dione; 16-alpha,17-alpha-Butylidenedioxy-11-beta,21-dihydroxy-1,4-pregnadiene-3,20-dione; 16alpha(R),17-(Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; 16alpha-,17alpha-butylidenedioxypregna-1,4-diene-11beta-,21-diol-3,20-dione; B 7777; Bidien; Budecort Inhaler; Budenofalk; Budeson; Budesonide (JAN/USAN/INN);Budesonide [USAN:INN:BAN:JAN]; Budesonide Easyhaler; Budesonide MMX; Budesonido; Budesonido [INN-Spanish]; Budesonidum; Budesonidum [INN-Latin]; Budiair; Cortivent; Dexbudesonide; Dexbudesonide [INN]; Entocort; Entocort (TN); Entocort EC; Entocort EC (TN); GionaEasyhaler; Horacort; Inflammide; MAP-0010; Micronyl; Miflonide; Noex (TN); Preferid; Pregna-1,4-diene-3,20-dione, 16,17-butylidenebis(oxy)-11,21-dihydroxy-, (11beta,16alpha(R))-,and 16alpha,17-((S)-Butylidenebis(oxy))-11beta,21-dihydroxypregna-1,4-diene-3,20-dione; Pulmaxan; Pulmaxan turbohaler; Pulmicort; Pulmicort (TN); Pulmicort Flexhaler; Pulmicort Nebuamp; Pulmicort Respules; Pulmicort Topinasal; Pulmicort turbuhaler; Respules; Rhinocort; Rhinocort (TN); Rhinocort Aqua; Rhinocort Turbuhaler; Rhinocort alpha; Rhinocort, Pulmicort , Entocort, Symbicort, Noex. Entocort EC, Budesonide; S 1320; S-1320; Spirocort; UDB; Unit dosebudesonide
Drug Type
Small molecular drug
Therapeutic Class
Antiinflammatory Agents
Structure
3D MOL 2D MOL
Formula
C25H34O6
Canonical SMILES
CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
InChI
InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
InChIKey
VOVIALXJUBGFJZ-KWVAZRHASA-N
CAS Number
CAS 51333-22-3
Pharmaceutical Properties Molecular Weight 430.5 Topological Polar Surface Area 93.1
Heavy Atom Count 31 Rotatable Bond Count 4
Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 6
XLogP
2.5
PubChem CID
5281004
PubChem SID
10321783 ,103455384 ,103914268 ,104170124 ,11466546 ,11467666 ,11486132 ,11528595 ,12013315 ,121360873 ,121362487 ,121363112 ,124749512 ,124800069 ,124886759 ,126627527 ,126651544 ,127278596 ,127278597 ,14807548 ,14929955 ,17404737 ,24278277 ,39289945 ,46504869 ,47646553 ,47720602 ,47869643 ,47943751 ,48169361 ,49698535 ,50105232 ,53777280 ,53789711 ,56394980 ,56422168 ,57357962 ,77787022 ,7847312 ,7978823 ,81092787 ,855541 ,85787937 ,8616471 ,90341081 ,90473637 ,92125441 ,92303636 ,92721807 ,93576669
ChEBI ID
ChEBI:3207
TTD Drug ID
D0Y7IU

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