General Information of Drug Transporter (DT)
DT ID DTD0258 Transporter Info
Gene Name SLC2A3
Transporter Name Glucose transporter type 3, brain
Gene ID
6515
UniProt ID
P11169
Exogenous factors (drugs, dietary constituents, etc.) Modulation of This DT (EGM)

Mycotoxins

  Aflatoxin B1

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Aflatoxin B1 results in decreased methylation of SLC2A3 3' UTR [65]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Aflatoxin B1 results in decreased methylation of SLC2A3 intron [65]

Regulation Mechanism

Transcription Factor Info

Biotoxin

  yessotoxin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

yessotoxin analog results in increased expression of SLC2A3 mRNA [54]

Regulation Mechanism

Transcription Factor Info

Approved Drug

  Bevacizumab

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Bevacizumab induces the transportation of Glucose by SLC2A3 [1]

Affected Drug/Substrate

Glucose Modulation Type Inducer

  Oxaliplatin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Oxaliplatin inhibits the expression of SLC2A3 [2]

Regulation Mechanism

via the inhibition of Transcriptional repressor protein YY1 (YY1) Transcription Factor Info

Cell System

Human colon carcinoma isolates

  Raloxifene Hydrochloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Raloxifene Hydrochloride affects the expression of SLC2A3 [3]

  Chlorpromazine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Chlorpromazine inhibits the expression of SLC2A3 [4]

  Clozapine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Clozapine inhibits the expression of SLC2A3 [4]

  Flecainide

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Flecainide inhibits the expression of SLC2A3 [4]

  Pentamidine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Pentamidine inhibits the expression of SLC2A3 [4]

  Sotalol

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Sotalol increases the expression of SLC2A3 [4]

  Thioridazine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Thioridazine inhibits the expression of SLC2A3 [4]

  Vandetanib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Vandetanib increases the expression of SLC2A3 [5]

  Tretinoin

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Tretinoin inhibits the expression of SLC2A3 [6]

  Gemcitabine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Gemcitabine increases the expression of SLC2A3 [7]

  Acetaminophen

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Acetaminophen inhibits the expression of SLC2A3 [8]

  DT Modulation2

Acetaminophen results in increased expression of SLC2A3 mRNA [63]

Regulation Mechanism

Transcription Factor Info

  Citalopram

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Citalopram inhibits the expression of SLC2A3 [9]

  Doxepin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Doxepin inhibits the expression of SLC2A3 [9]

  Bortezomib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Bortezomib increases the expression of SLC2A3 [10]

  Calcitriol

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Calcitriol increases the expression of SLC2A3 [11]

  Testosterone

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Testosterone increases the expression of SLC2A3 [11]

  Ampicillin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Ampicillin increases the expression of SLC2A3 [12]

  Niclosamide

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Niclosamide inhibits the expression of SLC2A3 [13]

  Zidovudine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Zidovudine inhibits the expression of SLC2A3 [15]

  Methotrexate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Methotrexate inhibits the expression of SLC2A3 [16]

  Caffeine

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Caffeine increases the expression of SLC2A3 [17]

  Carbamazepine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Carbamazepine affects the expression of SLC2A3 [18]

  Panobinostat

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Panobinostat increases the expression of SLC2A3 [19]

  Vorinostat

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Vorinostat increases the expression of SLC2A3 [19]

  Cisplatin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cisplatin increases the expression of SLC2A3 [20]

  Urethane

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Urethane inhibits the expression of SLC2A3 [21]

  Doxorubicin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Doxorubicin inhibits the expression of SLC2A3 [22]

  Avobenzone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Avobenzone increases the expression of SLC2A3 [23]

  Cannabidiol

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cannabidiol increases the expression of SLC2A3 [24]

  Sunitinib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Sunitinib increases the expression of SLC2A3 [25]

  Clomipramine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Clomipramine inhibits the expression of SLC2A3 [8]

  Amitriptyline

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Amitriptyline inhibits the expression of SLC2A3 [9]

  Fluoxetine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Fluoxetine inhibits the expression of SLC2A3 [9]

  Imipramine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Imipramine inhibits the expression of SLC2A3 [9]

  Ketoconazole

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Ketoconazole inhibits the expression of SLC2A3 [9]

  Loratadine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Loratadine inhibits the expression of SLC2A3 [9]

  Quinidine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Quinidine inhibits the expression of SLC2A3 [9]

  Sertraline

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Sertraline inhibits the expression of SLC2A3 [9]

  Tamoxifen

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Tamoxifen inhibits the expression of SLC2A3 [9]

  Amiodarone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Amiodarone inhibits the expression of SLC2A3 [27]

  Cyclosporine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cyclosporine inhibits the expression of SLC2A3 [28]

  Arsenic Trioxide

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Arsenic Trioxide increases the expression of SLC2A3 [29]

  Valproic Acid

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Valproic Acid increases the expression of SLC2A3 [30]

  Estradiol

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Estradiol increases the expression of SLC2A3 [31]

Regulation Mechanism

via enhancement of Cyclic AMP-responsive element-binding protein 1 (CREB1) Transcription Factor Info

Affected Drug/Substrate

Glucose Modulation Type Inducer

Cell System

Human neuroblastoma cells (SH-SY5Y)

Drug Marketed but not Approved by US FDA

  Demecolcine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Demecolcine increases the expression of SLC2A3 [14]

  Rotenone

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Rotenone inhibits the expression of SLC2A3 [26]

Drug in Phase 3 Trial

  torcetrapib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

torcetrapib increases the expression of SLC2A3 [41]

  Sulforafan

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Sulforafan increases the expression of SLC2A3 [47]

  Triclosan

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Triclosan inhibits the expression of SLC2A3 [53]

  Epigallocatechin gallate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Epigallocatechin gallate increases the expression of SLC2A3 [58]

Drug in Phase 2 Trial

  MS-275

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

MS-275 increases the expression of SLC2A3 [19]

  Bisphenol A

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Bisphenol A affects the expression of SLC2A3 [56]

Drug in Phase 1 Trial

  Chlorcyclizine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Chlorcyclizine inhibits the expression of SLC2A3 [4]

  WSM-3978G

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

WSM-3978G inhibits the expression of SLC2A3 [4]

  Dinitrochlorobenzene

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Dinitrochlorobenzene inhibits the expression of SLC2A3 [35]

  Quercetin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Quercetin inhibits the expression of SLC2A3 [12]

  Dihydrotestosterone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Dihydrotestosterone increases the expression of SLC2A3 [51]

  Sodium arsenite

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Sodium arsenite inhibits the expression of SLC2A3 [60]

  Trichostatin A

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Trichostatin A increases the expression of SLC2A3 [19]

Drug in Preclinical Test

  (+)-JQ1

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

(+)-JQ1 inhibits the expression of SLC2A3 [40]

Investigative Drug

  Tributyltin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Tributyltin inhibits the expression of SLC2A3 [35]

  Archazolid B

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Archazolid B increases the expression of SLC2A3 [43]

  SB-431542

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

SB-431542 increases the expression of SLC2A3 [44]

  Phenylmercuric Acetate

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Phenylmercuric Acetate increases the expression of SLC2A3 [19]

  PP242

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

PP242 inhibits the expression of SLC2A3 [54]

  Milchsaure

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Milchsaure affects the expression of SLC2A3 [55]

Patented Pharmaceutical Agent

  Eugenol

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Eugenol increases the expression of SLC2A3 [34]

  K-7174

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

K-7174 inhibits the expression of SLC2A3 [42]

  GSK-J4

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

GSK-J4 increases the expression of SLC2A3 [50]

Natural Product

  DT Modulation1

Caffeine affects the phosphorylation of SLC2A3 protein [82]

Regulation Mechanism

Transcription Factor Info

  Particulate Matter

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Particulate Matter increases the expression of SLC2A3 [38]

  Tobacco Smoke Pollution

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Tobacco Smoke Pollution inhibits the expression of SLC2A3 [59]

Environmental toxicant

  Resorcinol

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Resorcinol increases the expression of SLC2A3 [39]

  Polychlorinated dibenzodioxin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Polychlorinated dibenzodioxin inhibits the expression of SLC2A3 [12]

  Lead

           4 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 mRNA [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 protein [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 mRNA [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 protein [93]

Regulation Mechanism

Transcription Factor Info

Acute Toxic Substance

  trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride inhibits the expression of SLC2A3 [4]

  Uranium

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Uranium affects the expression of SLC2A3 [32]

  Nickel chloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Nickel chloride increases the expression of SLC2A3 [33]

  Cadmium

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cadmium inhibits the expression of SLC2A3 [36]

  Thimerosal

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Thimerosal inhibits the expression of SLC2A3 [48]

  Formaldehyde

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Formaldehyde increases the expression of SLC2A3 [49]

Carcinogen

  Benzo(a)pyrene

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Benzo(a)pyrene inhibits the expression of SLC2A3 [61]

  Arsenic

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sodium arsenate results in increased abundance of Arsenic which results in increased expression of SLC2A3 mRNA [71]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

sodium arsenite results in increased abundance of Arsenic co-treated with manganese chloride results in increased abundance of Manganese results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

sodium arsenite results in increased abundance of Arsenic which results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  Nickel

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Nickel results in increased expression of SLC2A3 mRNA [96]

Regulation Mechanism

Transcription Factor Info

Health and Environmental Toxicant

  Butyraldehyde

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Butyraldehyde inhibits the expression of SLC2A3 [45]

  tris(1,3-dichloro-2-propyl)phosphate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

tris(1,3-dichloro-2-propyl)phosphate inhibits the expression of SLC2A3 [46]

  Diethylhexyl Phthalate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Diethylhexyl Phthalate increases the expression of SLC2A3 [57]

Nanoparticle

  Silver nanoparticle

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Silver nanoparticle increases the expression of SLC2A3 [52]

Chemical Compound

  DT Modulation1

Flecainide results in increased expression of SLC2A3 mRNA [8]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Tretinoin results in increased expression of SLC2A3 mRNA [114]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Testosterone co-treated with Calcitriol results in increased expression of SLC2A3 mRNA [11]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Testosterone co-treated with Calcitriol results in increased expression of SLC2A3 mRNA [11]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Niclosamide results in increased expression of SLC2A3 mRNA [98]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Rotenone results in increased expression of SLC2A3 protein [109]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Tamoxifen affects the expression of SLC2A3 mRNA [3]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Estradiol co-treated with TGFB1 protein results in decreased expression of SLC2A3 mRNA [90]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Dinitrochlorobenzene results in increased expression of SLC2A3 mRNA [34]

Regulation Mechanism

Transcription Factor Info

  Dinitrofluorobenzene

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Dinitrofluorobenzene increases the expression of SLC2A3 [37]

  Pentanal

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Pentanal inhibits the expression of SLC2A3 [45]

  DT Modulation1

NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation1

Benzo(a)pyrene affects the methylation of SLC2A3 intron [65]

Regulation Mechanism

Transcription Factor Info

  4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide

         10 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 protein [44]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation6

NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation7

NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation8

NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation9

NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation10

NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  4-phenylenediamine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

4-phenylenediamine results in increased expression of SLC2A3 mRNA [35]

Regulation Mechanism

Transcription Factor Info

  abrine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

abrine results in decreased expression of SLC2A3 mRNA [62]

Regulation Mechanism

Transcription Factor Info

  Acetylcysteine

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Acetylcysteine inhibits the reaction epigallocatechin gallate results in increased expression of SLC2A3 mRNA [58]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Acetylcysteine inhibits the reaction epigallocatechin gallate results in increased expression of SLC2A3 protein [58]

Regulation Mechanism

Transcription Factor Info

  Acetylglucosamine

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Acetylglucosamine results in decreased expression of SLC2A3 mRNA [64]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Acetylglucosamine results in increased expression of SLC2A3 mRNA [64]

Regulation Mechanism

Transcription Factor Info

  Aldehydes

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Aldehydes results in decreased expression of SLC2A3 mRNA [66]

Regulation Mechanism

Transcription Factor Info

  amyloid beta-protein (1-40)

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

amyloid beta-protein (1-40) results in decreased expression of SLC2A3 protein [67]

Regulation Mechanism

Transcription Factor Info

  Antimony Potassium Tartrate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Antimony Potassium Tartrate results in increased abundance of antimonite which results in increased expression of SLC2A3 mRNA [68]

Regulation Mechanism

Transcription Factor Info

  Apigenin

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Apigenin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Apigenin results in decreased expression of SLC2A3 mRNA [70]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

Apigenin results in decreased expression of SLC2A3 protein [70]

Regulation Mechanism

Transcription Factor Info

  archazolid B

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

archazolid B results in increased expression of SLC2A3 mRNA [43]

Regulation Mechanism

Transcription Factor Info

  Asbestos, Crocidolite

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Asbestos, Crocidolite results in increased expression of SLC2A3 mRNA [73]

Regulation Mechanism

Transcription Factor Info

  Asbestos, Serpentine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Asbestos, Serpentine results in increased expression of SLC2A3 mRNA [74]

Regulation Mechanism

Transcription Factor Info

  avobenzone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

avobenzone results in increased expression of SLC2A3 mRNA [23]

Regulation Mechanism

Transcription Factor Info

  benzo(e)pyrene

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

benzo(e)pyrene results in increased methylation of SLC2A3 intron [65]

Regulation Mechanism

Transcription Factor Info

  beta-lapachone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

beta-lapachone results in increased expression of SLC2A3 mRNA [75]

Regulation Mechanism

Transcription Factor Info

  bisphenol A

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

bisphenol A affects the expression of SLC2A3 mRNA [56]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

bisphenol A results in decreased methylation of SLC2A3 gene [76]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

bisphenol A results in increased expression of SLC2A3 mRNA [77]

Regulation Mechanism

Transcription Factor Info

  bruceine D

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

bruceine D results in decreased expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

CTNNBIP1 protein affects the reaction bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  butyraldehyde

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

butyraldehyde results in decreased expression of SLC2A3 mRNA [45]

Regulation Mechanism

Transcription Factor Info

  Cadmium Chloride

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cadmium Chloride results in decreased expression of SLC2A3 mRNA [79]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Cadmium Chloride results in increased expression of SLC2A3 mRNA [80]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  chlorcyclizine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

chlorcyclizine results in decreased expression of SLC2A3 mRNA [4]

Regulation Mechanism

Transcription Factor Info

  chromic oxide

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  chromous chloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  cobaltous chloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

cobaltous chloride results in increased expression of SLC2A3 mRNA [83]

Regulation Mechanism

Transcription Factor Info

  Copper

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Organoselenium Compounds binds to Copper which results in increased expression of SLC2A3 mRNA [84]

Regulation Mechanism

Transcription Factor Info

  Cytochalasin B

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cytochalasin B inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  Dehydroascorbic Acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

SLC2A3 protein affects the transport of Dehydroascorbic Acid [86]

Regulation Mechanism

Transcription Factor Info

  Deoxyglucose

           5 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Cytochalasin B inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Galactose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

Glucose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

Maltose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  diallyl trisulfide

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

diallyl trisulfide results in increased expression of SLC2A3 mRNA [87]

Regulation Mechanism

Transcription Factor Info

  di-n-butylphosphoric acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

di-n-butylphosphoric acid affects the expression of SLC2A3 mRNA [88]

Regulation Mechanism

Transcription Factor Info

  dorsomorphin

           9 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation6

NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation7

NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation8

NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation9

NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  entinostat

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

entinostat results in increased expression of SLC2A3 mRNA [19]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  epigallocatechin gallate

           5 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Acetylcysteine inhibits the reaction epigallocatechin gallate results in increased expression of SLC2A3 mRNA [58]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Acetylcysteine inhibits the reaction epigallocatechin gallate results in increased expression of SLC2A3 protein [58]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

epigallocatechin gallate results in increased expression of SLC2A3 mRNA [58]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

epigallocatechin gallate results in increased expression of SLC2A3 protein [58]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

potassium chromate(VI) co-treated with epigallocatechin gallate results in increased expression of SLC2A3 mRNA [89]

Regulation Mechanism

Transcription Factor Info

  fisetin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

fisetin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  Fluorouracil

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

SLC2A3 protein affects the susceptibility to Fluorouracil [91]

Regulation Mechanism

Transcription Factor Info

  Galactose

           4 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Galactose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Glucose inhibits the reaction SLC2A3 protein results in increased transport of Galactose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

Maltose inhibits the reaction SLC2A3 protein results in increased transport of Galactose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

SLC2A3 protein results in increased transport of Galactose [85]

Regulation Mechanism

Transcription Factor Info

  Glucose

           4 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Glucose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Glucose inhibits the reaction SLC2A3 protein results in increased transport of Galactose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

INS protein co-treated with Glucose results in decreased expression of SLC2A3 protein [92]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

Kynurenic Acid inhibits the reaction INS protein co-treated with Glucose results in decreased expression of SLC2A3 protein [92]

Regulation Mechanism

Transcription Factor Info

  K 7174

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

K 7174 results in decreased expression of SLC2A3 mRNA [42]

Regulation Mechanism

Transcription Factor Info

  Kynurenic Acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Kynurenic Acid inhibits the reaction INS protein co-treated with Glucose results in decreased expression of SLC2A3 protein [92]

Regulation Mechanism

Transcription Factor Info

  Lactic Acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Lactic Acid affects the expression of SLC2A3 mRNA [55]

Regulation Mechanism

Transcription Factor Info

  lead acetate

           5 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 mRNA [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 protein [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 mRNA [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

PPIF protein affects the reaction lead acetate results in increased abundance of Lead which results in decreased expression of SLC2A3 protein [93]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  Luteolin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Luteolin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  Maltose

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Maltose inhibits the reaction SLC2A3 protein results in increased transport of Deoxyglucose [85]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Maltose inhibits the reaction SLC2A3 protein results in increased transport of Galactose [85]

Regulation Mechanism

Transcription Factor Info

  Manganese

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

manganese chloride results in increased abundance of Manganese which results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

sodium arsenite results in increased abundance of Arsenic co-treated with manganese chloride results in increased abundance of Manganese results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  manganese chloride

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

manganese chloride results in increased abundance of Manganese which results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

sodium arsenite results in increased abundance of Arsenic co-treated with manganese chloride results in increased abundance of Manganese results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  mercuric bromide

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

mercuric bromide results in increased expression of SLC2A3 mRNA [19]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  Methapyrilene

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Methapyrilene results in increased methylation of SLC2A3 intron [65]

Regulation Mechanism

Transcription Factor Info

  methylmercuric chloride

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

methylmercuric chloride results in decreased expression of SLC2A3 mRNA [94]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

methylmercuric chloride results in increased expression of SLC2A3 mRNA [94]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

NOG protein co-treated with methylmercuric chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  NCS 382

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

NCS 382 results in decreased expression of SLC2A3 mRNA [95]

Regulation Mechanism

Transcription Factor Info

  nickel chloride

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

nickel chloride results in increased expression of SLC2A3 mRNA [33]

Regulation Mechanism

Transcription Factor Info

  nickel sulfate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

nickel sulfate results in increased expression of SLC2A3 mRNA [97]

Regulation Mechanism

Transcription Factor Info

  nimbolide

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

nimbolide results in decreased expression of SLC2A3 mRNA [99]

Regulation Mechanism

Transcription Factor Info

  NVP-BKM120

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sotorasib co-treated with trametinib co-treated with NVP-BKM120 results in decreased expression of SLC2A3 mRNA [100]

Regulation Mechanism

Transcription Factor Info

  Oxazolone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Oxazolone results in increased expression of SLC2A3 mRNA [34]

Regulation Mechanism

Transcription Factor Info

  Oxygen

         10 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Apigenin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

CTNNBIP1 protein affects the reaction bruceine D affects the reaction Oxygen deficiency affects the expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

fisetin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

HIF1A protein affects the reaction Oxygen deficiency results in increased expression of SLC2A3 protein [101]

Regulation Mechanism

Transcription Factor Info

  DT Modulation6

Luteolin co-treated with Oxygen deficiency results in decreased expression of SLC2A3 mRNA [69]

Regulation Mechanism

Transcription Factor Info

  DT Modulation7

Oxygen deficiency affects the expression of SLC2A3 protein [78]

Regulation Mechanism

Transcription Factor Info

  DT Modulation8

Oxygen deficiency results in increased expression of SLC2A3 mRNA [102]

Regulation Mechanism

Transcription Factor Info

  DT Modulation9

Oxygen deficiency results in increased expression of SLC2A3 protein [101]

Regulation Mechanism

Transcription Factor Info

  DT Modulation10

ST6GAL1 protein promotes the reaction Oxygen deficiency results in increased expression of SLC2A3 mRNA [103]

Regulation Mechanism

Transcription Factor Info

  Palmitic Acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Palmitic Acid results in increased expression of SLC2A3 mRNA [104]

Regulation Mechanism

Transcription Factor Info

  p-Chloromercuribenzoic Acid

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

p-Chloromercuribenzoic Acid results in increased expression of SLC2A3 mRNA [19]

Regulation Mechanism

Transcription Factor Info

  PCI 5002

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

PCI 5002 co-treated with Zinc results in increased expression of SLC2A3 mRNA [105]

Regulation Mechanism

Transcription Factor Info

  pentanal

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

pentanal results in decreased expression of SLC2A3 mRNA [45]

Regulation Mechanism

Transcription Factor Info

  perfluorooctanoic acid

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

perfluorooctanoic acid results in decreased expression of SLC2A3 protein [106]

Regulation Mechanism

Transcription Factor Info

  Perhexiline

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Perhexiline results in decreased expression of SLC2A3 mRNA [4]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Perhexiline results in increased expression of SLC2A3 mRNA [8]

Regulation Mechanism

Transcription Factor Info

  PF-06840003

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

PF-06840003 inhibits the reaction MAPT protein mutant form results in decreased expression of SLC2A3 mRNA [107]

Regulation Mechanism

Transcription Factor Info

  Pioglitazone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Pioglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  potassium chromate(VI)

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

potassium chromate(VI) co-treated with epigallocatechin gallate results in increased expression of SLC2A3 mRNA [89]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

potassium chromate(VI) results in increased expression of SLC2A3 mRNA [89]

Regulation Mechanism

Transcription Factor Info

  resorcinol

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

resorcinol results in increased expression of SLC2A3 mRNA [39]

Regulation Mechanism

Transcription Factor Info

  Rosiglitazone

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Rosiglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Rosiglitazone inhibits the reaction tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  S-(1,2-dichlorovinyl)cysteine

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides results in decreased expression of SLC2A3 mRNA [110]

Regulation Mechanism

Transcription Factor Info

  Silicon Dioxide

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Silicon Dioxide results in decreased expression of SLC2A3 mRNA [111]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Silicon Dioxide results in increased expression of SLC2A3 mRNA [73]

Regulation Mechanism

Transcription Factor Info

  sodium arsenate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sodium arsenate results in increased abundance of Arsenic which results in increased expression of SLC2A3 mRNA [71]

Regulation Mechanism

Transcription Factor Info

  sodium arsenite

           5 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sodium arsenite co-treated with Cadmium Chloride co-treated with chromic oxide co-treated with chromous chloride co-treated with lead acetate results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

sodium arsenite results in decreased expression of SLC2A3 mRNA [81]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

sodium arsenite results in increased abundance of Arsenic co-treated with manganese chloride results in increased abundance of Manganese results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

sodium arsenite results in increased abundance of Arsenic which results in increased expression of SLC2A3 mRNA [72]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

sodium arsenite results in increased expression of SLC2A3 mRNA [112]

Regulation Mechanism

Transcription Factor Info

  sotorasib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sotorasib co-treated with trametinib co-treated with NVP-BKM120 results in decreased expression of SLC2A3 mRNA [100]

Regulation Mechanism

Transcription Factor Info

  sulforaphane

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sulforaphane results in increased expression of SLC2A3 mRNA [47]

Regulation Mechanism

Transcription Factor Info

  tert-Butylhydroperoxide

           6 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Pioglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Rosiglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

Rosiglitazone inhibits the reaction tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation4

tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation5

Troglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation6

Troglitazone inhibits the reaction tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  Tetrachlorodibenzodioxin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Tetrachlorodibenzodioxin results in decreased expression of SLC2A3 mRNA [113]

Regulation Mechanism

Transcription Factor Info

  trametinib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

sotorasib co-treated with trametinib co-treated with NVP-BKM120 results in decreased expression of SLC2A3 mRNA [100]

Regulation Mechanism

Transcription Factor Info

  tributyltin

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

tributyltin results in decreased expression of SLC2A3 mRNA [35]

Regulation Mechanism

Transcription Factor Info

  trichostatin A

           3 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC2A3 mRNA [48]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

trichostatin A affects the expression of SLC2A3 mRNA [115]

Regulation Mechanism

Transcription Factor Info

  DT Modulation3

trichostatin A results in increased expression of SLC2A3 mRNA [116]

Regulation Mechanism

Transcription Factor Info

  triphenyl phosphate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

triphenyl phosphate affects the expression of SLC2A3 mRNA [88]

Regulation Mechanism

Transcription Factor Info

  Troglitazone

           2 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Troglitazone co-treated with tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  DT Modulation2

Troglitazone inhibits the reaction tert-Butylhydroperoxide results in increased expression of SLC2A3 mRNA [108]

Regulation Mechanism

Transcription Factor Info

  uranyl acetate

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

uranyl acetate affects the expression of SLC2A3 mRNA [32]

Regulation Mechanism

Transcription Factor Info

  Vanadates

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

Vanadates results in increased expression of SLC2A3 mRNA [117]

Regulation Mechanism

Transcription Factor Info

  vanadium pentoxide

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

vanadium pentoxide affects the expression of SLC2A3 mRNA [118]

Regulation Mechanism

Transcription Factor Info

  vandetanib

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

vandetanib results in increased expression of SLC2A3 mRNA [5]

Regulation Mechanism

Transcription Factor Info

  warangalone

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

warangalone analog results in decreased expression of SLC2A3 protein [119]

Regulation Mechanism

Transcription Factor Info

  Zinc

           1 DT Activity Modulations Related to This Exogenous Factor Click to Show/Hide the Full List

  DT Modulation1

PCI 5002 co-treated with Zinc results in increased expression of SLC2A3 mRNA [105]

Regulation Mechanism

Transcription Factor Info
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