Detail Information of Exogenous Modulation
General Information of Drug Transporter (DT) | |||||
---|---|---|---|---|---|
DT ID | DTD0180 Transporter Info | ||||
Gene Name | SLC25A20 | ||||
Transporter Name | Carnitine/acylcarnitine translocase | ||||
Gene ID | |||||
UniProt ID | |||||
Exogenous factors (drugs, dietary constituents, etc.) Modulation of This DT (EGM) | |||||
---|---|---|---|---|---|
Chemical Compound |
|||||
DT Modulation1 |
Testosterone co-treated with Calcitriol results in increased expression of SLC25A20 mRNA | [4] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Valproic Acid affects the expression of SLC25A20 mRNA | [45] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Valproic Acid results in increased expression of SLC25A20 mRNA | [46] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
Valproic Acid results in increased methylation of SLC25A20 gene | [9] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Testosterone co-treated with Calcitriol results in increased expression of SLC25A20 mRNA | [4] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
Acetylcysteine inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Dithioerythritol inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Glutathione inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation1 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
2,5,2',5'-tetrachlorobiphenyl |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
2,5,2',5'-tetrachlorobiphenyl results in decreased expression of SLC25A20 mRNA | [27] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Acetylcysteine |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acetylcysteine inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Acetylcysteine inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
aristolochic acid I |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
aristolochic acid I results in increased expression of SLC25A20 mRNA | [30] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
benzo(e)pyrene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
benzo(e)pyrene results in decreased methylation of SLC25A20 intron | [29] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
bisphenol AF |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
bisphenol AF results in increased expression of SLC25A20 protein | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
bisphenol B |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
bisphenol B results in increased expression of SLC25A20 protein | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
bisphenol F |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
bisphenol F results in increased expression of SLC25A20 protein | [26] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Cadmium Chloride |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC25A20 mRNA | [32] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
chloroacetaldehyde |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
chloroacetaldehyde results in increased expression of SLC25A20 mRNA | [6] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
chromium hexavalent ion |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
chromium hexavalent ion results in decreased expression of SLC25A20 mRNA | [33] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
dicrotophos |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
dicrotophos results in decreased expression of SLC25A20 mRNA | [19] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
di-n-butylphosphoric acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
di-n-butylphosphoric acid affects the expression of SLC25A20 mRNA | [34] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Dithioerythritol |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dithioerythritol inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Dithioerythritol inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Diuron |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Diuron results in decreased expression of SLC25A20 mRNA | [35] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
dorsomorphin |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in increased expression of SLC25A20 mRNA | [28] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
epigallocatechin gallate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
potassium chromate(VI) co-treated with epigallocatechin gallate results in decreased expression of SLC25A20 mRNA | [36] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Farnesol |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Farnesol analog co-treated with Oleic Acid results in increased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
fenofibric acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
fenofibric acid binds to PPARA protein which results in increased expression of SLC25A20 mRNA | [37] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
FR900359 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
FR900359 results in increased phosphorylation of SLC25A20 protein | [38] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Glutathione |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Glutathione inhibits the reaction Mercuric Chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Glutathione inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
glycidyl methacrylate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
glycidyl methacrylate results in decreased expression of SLC25A20 protein | [39] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
GW 4064 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
GW 4064 co-treated with Oleic Acid results in decreased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
GW 7647 |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
GW 7647 co-treated with Oleic Acid results in increased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
GW 7647 results in increased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Methapyrilene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methapyrilene results in decreased methylation of SLC25A20 intron | [29] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
methylmercuric chloride |
4 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acetylcysteine inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
Dithioerythritol inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
Glutathione inhibits the reaction methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation4 |
methylmercuric chloride results in decreased activity of SLC25A20 protein | [1] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Okadaic Acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Okadaic Acid results in decreased expression of SLC25A20 mRNA | [41] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Oleic Acid |
3 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Farnesol analog co-treated with Oleic Acid results in increased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
GW 4064 co-treated with Oleic Acid results in decreased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation3 |
GW 7647 co-treated with Oleic Acid results in increased expression of SLC25A20 mRNA | [23] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Oxygen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Oxygen deficiency results in decreased expression of SLC25A20 mRNA | [6] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
perfluorododecanoic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
perfluorododecanoic acid results in decreased expression of SLC25A20 mRNA | [16] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
perfluorooctanoic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
perfluorooctanoic acid results in increased expression of SLC25A20 mRNA | [42] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
potassium chromate(VI) |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
potassium chromate(VI) co-treated with epigallocatechin gallate results in decreased expression of SLC25A20 mRNA | [36] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
DT Modulation2 |
potassium chromate(VI) results in decreased expression of SLC25A20 mRNA | [36] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
S-(1,2-dichlorovinyl)cysteine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides which results in increased expression of SLC25A20 mRNA | [43] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
sodium arsenite |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
sodium arsenite results in increased expression of SLC25A20 mRNA | [44] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Tetrachlorodibenzodioxin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tetrachlorodibenzodioxin results in increased expression of SLC25A20 mRNA | [3] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
trichostatin A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
trichostatin A affects the expression of SLC25A20 mRNA | [20] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Mycotoxins |
|||||
aflatoxin B2 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
aflatoxin B2 results in decreased methylation of SLC25A20 intron | [29] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Approved Drug |
|||||
Copper Sulfate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Copper Sulfate inhibits the expression of SLC25A20 | [2] | |||
Estradiol |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Estradiol inhibits the expression of SLC25A20 | [3] | |||
Testosterone |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Testosterone increases the expression of SLC25A20 | [4] | |||
Zidovudine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Zidovudine increases the expression of SLC25A20 | [5] | |||
Cidofovir |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cidofovir increases the expression of SLC25A20 | [6] | |||
Ifosfamide |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Ifosfamide increases the expression of SLC25A20 | [6] | |||
Rosiglitazone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Rosiglitazone inhibits the expression of SLC25A20 | [6] | |||
Urethane |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Urethane inhibits the expression of SLC25A20 | [7] | |||
Acetaminophen |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Acetaminophen inhibits the expression of SLC25A20 | [8] | |||
Valproic Acid |
5 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Valproic Acid inhibits the expression of SLC25A20 | [9] | |||
Sunitinib |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Sunitinib inhibits the expression of SLC25A20 | [10] | |||
Tretinoin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tretinoin increases the expression of SLC25A20 | [11] | |||
Cyclosporine |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cyclosporine inhibits the expression of SLC25A20 | [6] | |||
Calcitriol |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Calcitriol increases the expression of SLC25A20 | [12] | |||
Fenofibrate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Fenofibrate increases the expression of SLC25A20 | [6] | |||
Cisplatin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cisplatin increases the expression of SLC25A20 | [13] | |||
Drug Marketed but not Approved by US FDA |
|||||
Clodronic Acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Clodronic Acid increases the expression of SLC25A20 | [6] | |||
Drug in Phase 2 Trial |
|||||
Bisphenol B |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Bisphenol B increases the expression of SLC25A20 | [26] | |||
Drug in Phase 1 Trial |
|||||
Quercetin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Quercetin inhibits the expression of SLC25A20 | [14] | |||
Trichostatin A |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Trichostatin A affects the expression of SLC25A20 | [20] | |||
Dihydrotestosterone |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dihydrotestosterone increases the expression of SLC25A20 | [22] | |||
Drug in Preclinical Test |
|||||
Perfluorododecanoic acid |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Perfluorododecanoic acid inhibits the expression of SLC25A20 | [16] | |||
Investigative Drug |
|||||
Phenylmercuric Acetate |
2 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Phenylmercuric Acetate increases the expression of SLC25A20 | [18] | |||
Patented Pharmaceutical Agent |
|||||
GSK-J4 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
GSK-J4 inhibits the expression of SLC25A20 | [21] | |||
GW-7647 |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
GW-7647 increases the expression of SLC25A20 | [23] | |||
Natural Product |
|||||
Thapsigargin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Thapsigargin increases the expression of SLC25A20 | [15] | |||
Tobacco Smoke Pollution |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Tobacco Smoke Pollution increases the expression of SLC25A20 | [25] | |||
Environmental toxicant |
|||||
Mercury ion |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Mercury ion inhibits the activity of SLC25A20 (IC50 = 90 microM) | [1] | |||
Cell System |
Human cervical cancer cell line (Hela)-CACT | ||||
Methyl mercury ion |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Methyl mercury ion inhibits the activity of SLC25A20 (IC50 = 1237 microM) | [1] | |||
Cell System |
Human cervical cancer cell line (Hela)-CACT | ||||
Polychlorinated dibenzodioxin |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Polychlorinated dibenzodioxin increases the expression of SLC25A20 | [3] | |||
Bisphenol F |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Bisphenol F increases the expression of SLC25A20 | [26] | |||
Acute Toxic Substance |
|||||
Mercuric Chloride |
5 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Mercuric Chloride inhibits the activity of SLC25A20 | [1] | |||
Carcinogen |
|||||
Benzo(a)pyrene |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Benzo(a)pyrene inhibits the expression of SLC25A20 | [24] | |||
Arsenic |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Arsenic affects the methylation of SLC25A20 gene | [31] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Cadmium |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Cadmium Chloride results in increased abundance of Cadmium which results in increased expression of SLC25A20 mRNA | [32] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Nickel |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Nickel results in decreased expression of SLC25A20 mRNA | [40] | |||
Regulation Mechanism |
Transcription Factor Info | ||||
Pesticide/Insecticide |
|||||
Dicrotophos |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
Dicrotophos inhibits the expression of SLC25A20 | [19] | |||
Health and Environmental Toxicant |
|||||
tris(1,3-dichloro-2-propyl)phosphate |
1 DT Activity Modulations Related to This Exogenous Factor | Click to Show/Hide the Full List | |||
DT Modulation1 |
tris(1,3-dichloro-2-propyl)phosphate inhibits the expression of SLC25A20 | [17] | |||
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